Results 61 to 70 of about 42,998 (266)

Efficacy and safety of cannabinoids in the treatment of spasticity in multiple sclerosis: A systematic review of randomized clinical trials

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to evaluate the efficacy and safety of cannabinoids for the treatment of MS‐related spasticity. Methods Systematic searches were conducted in PubMed, EMBASE, and LILACS on 2 December 2025. Randomized controlled trials evaluating natural or synthetic cannabinoids for MS‐related spasticity were included.
Letícia Hamm‐Buiar, Daniela Gorski, Marcela Harumi Kagueiama, Astrid Wiens   +3 more
wiley   +1 more source

An ETH‐LAD trip with unfavourable consequences: A case report

British Journal of Clinical Pharmacology, EarlyView.
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler, Michaela Sommer, Annette Zschiesche, Anne Stürzebecher, Christina Grumann, Volker Auwärter, Maren Hermanns‐Clausen   +6 more
wiley   +1 more source

Evaluación Experimental de los Efectos Agudos, Tolerancia Crónica y Especificidad Contextual de la Tolerancia al Cannabis en Indicadores Locomotores

Psykhe, 2023
La evaluación experimental de la tolerancia al cannabis, entendida como el decremento en la respuesta a una cantidad específica de dicha droga luego de repetidas administraciones, ha carecido hasta el momento de una aproximación asociativa, centrándose ...
Felipe I. Varas, Esperanza Ibáñez Jiménez, Camila Aguilar Contreras, Simón Ramírez, Felipe Alfaro, Francisca Bertin Johnson, Jonathan Badilla, Gonzalo Miguez, Vanetza Quezada Scholz, Mario A. Laborda   +9 more
doaj  

Lewis‐Acidic Properties and Catalytic Behavior of Hydroboration‐ and Diolysis‐Derived NHC‐Stabilized Borenium Cations

Chemistry – A European Journal, EarlyView.
A series of thirteen (N‐heterocyclic carbene) NHC‐stabilized borenium cations is synthesized from NHC→BH3 complexes via hydroboration and condensation with diols. The novel compounds are fully characterized. Eight crystal structures are presented. Kinetic and NMR data show how the structural features translate to catalytic activity in hydrosilylation ...
Michał Jakubczyk, Michaela Buziková, Matouš Kloda, Miroslava Litecká, Karel Škoch   +4 more
wiley   +1 more source

Novel molecular changes induced by Nrg1 hypomorphism and Nrg1-cannabinoid interaction in adolescence: a hippocampal proteomic study in mice.

Frontiers in Cellular Neuroscience, 2013
Neuregulin 1 (NRG1) is linked to an increased risk of developing schizophrenia and cannabis dependence. Mice that are hypomorphic for Nrg1 (Nrg1 HET mice) display schizophrenia-relevant behavioural phenotypes and aberrant expression of serotonin and ...
Jarrah R Spencer, Jarrah R Spencer, Keturah M.E. Darbyshire, Aurelie A. Boucher, Mohammed A. Kashem, Leonora E. Long, Leonora E. Long, Leonora E. Long, Iain S. McGregor, Tim eKarl, Tim eKarl, Tim eKarl, Jonathon Carl Arnold, Jonathon Carl Arnold, Jonathon Carl Arnold   +14 more
doaj   +1 more source

Carbon Anodes for Low‐Temperature Nonaqueous Alkali Metal‐Ion Batteries

EcoEnergy, EarlyView.
This review summarizes recent progress in carbon anodes for low‐temperature nonaqueous alkali‐metal ion batteries. Fundamental thermodynamic and kinetic limitations are examined, alongside a systematic discussion of graphite, hard carbon, and emerging carbon architectures.
Zhichun Miao, Dandan Yu, Guojie Liu, Yuyang Qin, Jingyun Mou, Wenlong Song, Lu Shi, Zengqin Xiao, Xin Yuan, Huayu Chen, Laishun Qin, Da Chen   +11 more
wiley   +1 more source

Medical Cannabis in Children

Rambam Maimonides Medical Journal, 2020
The use of medical cannabis in children is rapidly growing. While robust evidence currently exists only for pure cannabidiol (CBD) to treat specific types of refractory epilepsy, in most cases, artisanal strains of CBD-rich medical cannabis are being ...
Adi Aran, Dalit Cayam-Rand
doaj   +1 more source

Hydrogen‐Enriched Tri‐Fuel Combustion for Low‐Carbon Engines at Medium Engine Load: A Comprehensive CFD Analysis

Energy Science &Engineering, EarlyView.
CFD analysis of a diesel–CH4–H2 tri‐fuel engine shows that increasing hydrogen energy share (HES) enhances mixing and accelerates combustion, improving pressure, efficiency, and reducing CO and soot. At 60% HES, ISFC improves 26.2%, soot drops 95%, while NOx increases due to higher temperatures. ABSTRACT The global commitment to achieve net‐zero carbon
Md. Ifthaker Alam, Tafsirul Hassan, Md Imtiaz Hossen, Md. Shaib Hossain, Bandhon Saha Bijoy   +4 more
wiley   +1 more source

Meniscus‐guided organic semiconductor single crystals: From fluid dynamics to morphology control and multifunctional applications

FlexMat, EarlyView.
Centered on the multiscale meniscus, this review dissects mass transport in meniscus‐guided coating into parallel and lateral components. By analyzing the balance of multiple factors during crystallization, it establishes a clear morphology‐performance relationship.
Yumeng Wang, Shengnan Chen, Lutong Guo, Lujing Shao, Zhenhua Li, Hao Liu, Yanlin Song, Yali Qiao   +7 more
wiley   +1 more source

Cannabis use associated with high-risk drug use among Palestinians: An emerging health risk

Population Medicine
Introduction The West Bank has seen an increase in cannabis use, but there are few studies on the prevalence and factors associated with tetrahydrocannabinol (THC) use among Palestinians. The aim of this study was to examine the prevalence of THC use and
Basma Damiri, Saed Bilbeisi, Majdeddin MohammedAli, Mohab Najjar   +3 more
doaj   +1 more source