Results 71 to 80 of about 68,648 (313)

Cannabinoids, Blood–Brain Barrier, and Brain Disposition

Pharmaceutics, 2020
Potential therapeutic actions of the cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are based on their activity as analgesics, anti-emetics, anti-inflammatory agents, anti-seizure compounds.
Fabrizio Calapai, Luigi Cardia, Emanuela Elisa Sorbara, Michele Navarra, Sebastiano Gangemi, Gioacchino Calapai, Carmen Mannucci   +6 more
doaj   +1 more source

Simultaneous quantification of delta-9-THC, THC-acid A, CBN and CBD in seized drugs using HPLC-DAD

, 2014
An HPLC-DAD method for the quantitative analysis of Δ(9)-tetrahydrocannabinol (THC), Δ(9)-tetrahydrocannabinolic acid-A (THCA-A), cannabidiol (CBD), and cannabinol (CBN) in confiscated cannabis products has been developed, fully validated and applied to ...
König, Stefan, Bernhard, Werner, Weinmann, Wolfgang, Ambach, Lars, Broillet, Alain, Penitschka, Franziska   +5 more
core   +1 more source

THC-consumption_data_202009.csv.tar.gz

, 2022
consumption_data_202009 ...
Sergio Nesmachnow (10819728), Gustavo Alvez (10819734), Juan Pablo Chavat (10819725), Jorge Graneri (10819731)   +3 more
core   +1 more source

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source

THC-exposed sperm maintain acrosome integrity.

Representative scatter plots of sperm, co-stained with FITC-PNA and PI, and treated with (A) control, (B) vehicle, (C) Low-THC (0.032μM), (D) Mid-THC (0.32μM), (E) High-THC (4.8μM) or (F) calcium ionophore (10μM).
Reem Sabry (14022063), Jibran Y. Khokhar (5591024), Laura A. Favetta (14022066), Ola S. Davis (15243193), Vivien B. Truong (15243190), Alexander G. Kuzma-Hunt (18264689)   +5 more
core   +1 more source

Intravitreal ranibizumab injection for choroidal neovascularization in Strumpell-Lorrain Syndrome

, 2012
Strumpell-Lorrain syndrome, or hereditary spastic paraplegia is a genetic disease of the central nervous system affecting the spinal cord and cerebellum.
Baglin G, Tran THC, QUERQUES , GIUSEPPE   +2 more
core   +1 more source

THC-consumption_data_202010.csv.tar.gz

, 2022
consumption_data_202010 ...
Sergio Nesmachnow (10819728), Gustavo Alvez (10819734), Juan Pablo Chavat (10819725), Jorge Graneri (10819731)   +3 more
core   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

SPE-GC-MS determination of THC, THC-OH and THC-COOH in urine samples

Arhiv za higijenu rada i toksikologiju, 2012
Cannabis is the most commonly used illicit drug in the world. Therefore, there is a great demand for reliable and sensitive methods for determining their presence in biological samples. Its use is detected by determining the presence of the main active compound Δ9-tetrahydrocannabinol (THC) and its metabolites 11-hydroxy-Δ9-tetrahydrocannabinol (THC-OH)
Nestić, Marina, Babić, Sandra, Mutavdžić Pavlović, Dragana, Sutlović, Davorka   +3 more
openaire   +2 more sources

Toxicological properties of Δ9-tetrahydrocannabinol and cannabidiol

Arhiv za Higijenu Rada i Toksikologiju, 2020
Cannabis sativa L. contains more than 100 phytocannabinoids that can interact with cannabinoid receptors CB1 and CB2. None of the cannabinoid receptor ligands is entirely CB1- or CB2-specific. The effects of cannabinoids therefore differ not just because
Černe Katarina
doaj   +1 more source