Results 171 to 180 of about 133,879,868 (285)

Warburg-effect phenotype: Regulation by acidification and lactate accumulation

Lactate accumulation and acidification in tumours are a cancer hallmark associated with the Warburg effect. Lactic acidosis correlates with cancer malignancy, and the benefit it offers to tumours has been the subject of numerous hypotheses.
Kolkman, Maxime
core  

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

ALKBH2 promotes the Warburg effect and bladder cancer progression under hypoxic conditions via the PI3K/AKT pathway. [PDF]

Clin Exp Med
Yang Z, Ma J, Qiang Z, Xie W, Jiao L, Hu Z, Zhang T, Zhang L, Lv J, Yue F, Chen G.   +10 more
europepmc   +1 more source

Advanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial Intelligence

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hepatocytes perform essential physiological functions in the human body. Gaining more profound insight into the liver structure, diseases, and physiology by using in vitro models can help to propose more relevant clinical applications. Conventional in vitro liver models, such as two‐dimensional (2D) cell cultures, fail to adequately replicate ...
Seyedeh Kiana Teymorian, Pedram Asadi Sarabi, Abbas Piryaei, Massoud Vosough   +3 more
wiley   +1 more source

Tumor metabolic plasticity in therapy resistance: from the Warburg effect to mitochondrial hijacking. [PDF]

Theranostics
Tzeng YT, Raj EN, Cheng SH, Yong SB, Lin SC, Peng RW, Li CJ.   +6 more
europepmc   +1 more source

pyFDRT: An open‐source Python tool for Fourier‐transform analysis of the distribution of relaxation times in electrochemical impedance spectra

Bulletin of the Korean Chemical Society, EarlyView.
pyFDRT is an open‐source tool that converts an impedance spectrum into a quantitative equivalent circuit. Its Fourier‐transform stage requires no discretization basis or regularization parameter, and the non‐negative refinement selects its own parameters, and an information criterion determines the relaxation process count.
Chung‐Yul Yoo, Jaeku Park, Jeongjin Kim   +2 more
wiley   +1 more source

MiR-381-3p inhibits Warburg effect and progression in osteosarcoma via targeting PFKFB3. [PDF]

World J Surg Oncol
Jiang H, Wu J, Wang C, Xia J, Tao Y, Wan Z, Li D, Duan W, Weng Y, Zhang Y.   +9 more
europepmc   +1 more source

Near‐infrared light‐activated aptamer‐based nanoprobe for spatiotemporally resolved detection of L‐lactate in colorectal cancer

BMEMat, EarlyView.
A near‐infrared (NIR) light‐activated “lock‐key” nanodevice is reported for spatiotemporally resolved detection of intratumoral L‐lactate. The system stays silent until deep‐penetrating NIR light remotely unlocks its function, allowing for precise sensing within tumors.
Siyu Pan, Xuanyi Lu, Wenjie Yang, Yunhui Peng, Lingfu Deng, Shuai Zha, Xueyang Fang, Guochen Bao, Lijun Jiang   +8 more
wiley   +1 more source

The Warburg Effect Redefined: A Kinetic and Regulatory Perspective. [PDF]

Cureus
Vayakkattil AB, Pazhanchery AS, Andrews S, Vayakkattil U.   +3 more
europepmc   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source