Results 21 to 30 of about 5,021 (275)
Micronization of Thebaine Extracted from Papaver bracteatum Lindl. Using Supercritical Fluid Technology [PDF]
BACKGROUND Thebaine, as a main opiate alkaloid extracted from papaveraceae plants, is widely used in the synthesis of many pharmaceutical ingredients such as buprenorphine, naltrexone, naloxone, and hydrocodone.
Hamze Salehi+2 more
openalex +2 more sources
Chemiluminescence determination of pethidine hydrochloride and thebaine alkaloides [PDF]
The aim of this work was finding new flurescent dyes as sensitizers for chemiluminescence (CL) determination some of narcotics. In this way 6 different dyes incloding rhodamine 6G, brilliant blue, orange G, chromatrope, eosinY and [Ru(phen)3]2+ and 14 ...
Massoud Karimi+2 more
doaj +1 more source
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares+5 more
wiley +1 more source
The adsorption and surface ionization of thebaine molecules (C19H21O3N) c m/z=311 on the surface of oxidized tungsten was studied by non-stationary methods of voltage modulation and flux modulation under the same experimental conditions using a high ...
Rakhmanov G.T., Usmanov D.T.
semanticscholar +1 more source
Diels-Alder Adducts of Morphinan-6,8-Dienes and Their Transformations. [PDF]
6,14-ethenomorphinans are semisynthetic opiate derivatives containing an ethylene bridge between positions 6 and 14 in ring-C of the morphine skeleton that imparts a rigid molecular structure.
Marton J+5 more
europepmc +3 more sources
Synthesis of Nororipavine and Noroxymorphone via N- and O-Demethylation of Iron Tricarbonyl Complex of Thebaine [PDF]
Aleš Machara+4 more
openalex +2 more sources
A unique diene moiety of the alkaloid thebaine enables its successful application in the Diels–Alder reaction with ethylene derivatives for producing the adducts that can serve as precursors for a whole class of opioids used in medicine.
I. V. Sandulenko
semanticscholar +1 more source
Preparative Scale Applications of C−H Activation in Medicinal Chemistry
This review covers examples where C−H activation has been implemented on a preparative synthetic scale for the synthesis of drugs/drug candidates. Key features of the optimization process, challenges and potential of such methods in the pharmaceutical industry are discussed for various metals and transformations.
Rita de Jesus+2 more
wiley +1 more source
Investigation of Alkaloids in Opium Poppy (Papaver somniferum L.) Varieties and Hybrids
This study aimed to investigate the proportions of morphine, thebaine, noscapine, codeine, oripavine and papaverine alkaloids in poppy varieties and hybrids. Nine parents and 36 hybrid lines were used in the trial.
Levent Yazici, Güngör Yılmaz
doaj +1 more source