Results 41 to 50 of about 3,256 (222)

Thiol-reactive analogues of galanthamine, codeine and morphine as potential probes to interrogate allosteric binding within nAChRs [PDF]

open access: yes, 2016
Alkaloids including galanthamine (1) and codeine (2) are reported to be positive allosteric modulators of nicotinic acetylcholine receptors (nAChRs) but the binding sites responsible for this activity are not known with certainty.
Balle, Thomas   +3 more
core   +1 more source

The Effect of L-tyrosine on Thebaine Production in Cell Suspension Culture of Iranian Poppy (Papaver bracteatum)

open access: yesJournal of Medicinal Plants, 2016
Background: Using of elicitors and different compounds in cell suspension culture is an effective strategy for enhancement and improvement of important secondary metabolites production in in vitro conditions.
R Farjaminezhad   +3 more
doaj  

Optimization of Thebaine Production using Adventitious Roots of Papaver bracteatum Lindle. by Alteration of Aeration Volume and Temperature in Bioreactor

open access: yesJournal of Medicinal Plants, 2019
Background: Nowadays, the optimization of the culture conditions in bioreactors is considered as an approach to produce secondary metabolites such as thebaine.
N Qavami   +5 more
doaj  

High variations of the thebaine concentrations in Iranian poppy (Papaver bracteatum Lindl.) from various regions in Iran

open access: yesJournal of Applied Botany and Food Quality
This paper aims to contribute reliable information to promote the pharmacological utilization of Papaver bracteatum by analyzing its wild population in Iran. For this purpose, 27 Iranian poppy specimens from 7 provinces of Iran were analyzed.
Mahdi Yahyazadeh   +14 more
doaj   +1 more source

Synthesis of Morphinan Alkaloids in Saccharomyces cerevisiae. [PDF]

open access: yesPLoS ONE, 2015
Morphinan alkaloids are the most powerful narcotic analgesics currently used to treat moderate to severe and chronic pain. The feasibility of morphinan synthesis in recombinant Saccharomyces cerevisiae starting from the precursor (R,S)-norlaudanosoline ...
Elena Fossati   +4 more
doaj   +1 more source

Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014–2023)

open access: yesChemistry &Biodiversity, Volume 22, Issue 8, August 2025.
This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Victor Menezes Sipoloni   +5 more
wiley   +1 more source

Improved evaluation method for reliable distinction of poppy (Papaver somniferum L.) cultivars

open access: yesInternational Journal of Horticultural Science, 1999
Investigating seven Hungarian standard cultivars (i.e. 'A1’, 'Kék Gemona', '13C-2`,'Kék Duna', `Kompolti M’, `Gödi N', 'Kozmosz) it was proved that for the reliable distinction between cultivars a complex analysis is necessitated. Because of the large
J. Bernáth, J. Bakó, F. Petheő
doaj   +1 more source

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

open access: yesChemistryEurope, Volume 3, Issue 4, July 14, 2025.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

Protection of naringenin chalcone by a pathogenesis‐related 10 protein promotes flavonoid biosynthesis in Marchantia polymorpha

open access: yesNew Phytologist, Volume 247, Issue 1, Page 233-248, July 2025.
Summary Pathogenesis‐related (PR) proteins are diverse stress‐ or pathogen‐induced proteins. Some are associated with specialised metabolism, including proposed functions for anthocyanin biosynthesis. However, data are limited to a few angiosperm species, and the mode(s) of action are uncertain.
Yanfei Zhou   +8 more
wiley   +1 more source

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