Results 41 to 50 of about 3,781 (264)
Postmortem tissue distribution of morphine and its metabolites in a series of heroin related deaths [PDF]
, 2018 The abuse of heroin (diamorphine) and heroin deaths are growing around the world. The interpretation of the toxicological results from suspected heroin deaths is notoriously difficult especially in cases where there may be limited samples.
Beer, Lewis J. +6 more
core +5 more sources
Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
Nature Communications, 2016 Opiates—the gold standard for pain relief—are currently produced by extraction from opium poppies. Here the authors show that bacteria can serve as an efficient and flexible platform for the production of opiates by demonstrating the total synthesis of ...
Akira Nakagawa +9 more
doaj +1 more source
In Vitro Polyploidy Induction in Persian Poppy (Papaver bracteatum Lindl.)
Caryologia, 2020 Papaver bracteatum Lindl. grows as a wild perennial medicinal plant in Northern Iran and is known mainly for its high amounts of the pharmaceutically valuable alkaloid of thebaine. In vitro production of tetraploid P.
Saeed Tarkesh Esfahani +2 more
doaj +1 more source
A Systematic Review on Main Chemical Constituents of Papaver bracteatum
Journal of Medicinal Plants, 2015 Papaver bracteatum Lindly (Papaveraceae) is an endemic species of Iran which has economic importance in drug industries. The main alkaloid of the plant is thebaine which is used as a precursor of the semi-synthetic and synthetic compounds including ...
M Soleymankhani +5 more
doaj
Frontiers in Microbiology, 2019 Secondary metabolite biosynthesis in medicinal plants is multi-step cascade known to be modulated by associated endophytes. While a single endophyte is not able to upregulate all biosynthetic steps, limiting maximum yield achievement.
Tania Ray +5 more
doaj +1 more source
Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014–2023)
Chemistry &Biodiversity, Volume 22, Issue 8, August 2025.This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Victor Menezes Sipoloni +5 more
wiley +1 more source
The harmonized system: amendments and their impact on WTO members' schedules [PDF]
, 2008 The Harmonized System is normally amended by the World Customs Organization every four to six years. These amendments pose considerable challenges for the WTO and its Members.
Yu, Dayong
core +1 more source
Journal of Medicinal Plants, 2019 Background: Nowadays, the optimization of the culture conditions in bioreactors is considered as an approach to produce secondary metabolites such as thebaine.
N Qavami +5 more
doaj
Journal of Applied Botany and Food QualityThis paper aims to contribute reliable information to promote the pharmacological utilization of Papaver bracteatum by analyzing its wild population in Iran. For this purpose, 27 Iranian poppy specimens from 7 provinces of Iran were analyzed.
Mahdi Yahyazadeh +14 more
doaj +1 more source
Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis
ChemistryEurope, Volume 3, Issue 4, July 14, 2025.This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley +1 more source