Results 11 to 20 of about 39,448 (266)

Thermogenesis by THADA [PDF]

open access: yesDevelopmental Cell, 2017
THADA has been associated with cold adaptation and diabetes in humans, but the cellular and molecular basis of its function has been unknown. Moraru and colleagues (2017) report in this issue of Developmental Cell that it triggers thermogenesis by uncoupling ATP hydrolysis from calcium transport into the endoplasmic reticulum.
Chatterjee, Nirmalya, Perrimon, Norbert
openaire   +3 more sources

Transcriptome Profiles of the Liver in Two Cold-Exposed Sheep Breeds Revealed Different Mechanisms and Candidate Genes for Thermogenesis

open access: yesGenetics Research, 2021
Cold-induced thermogenesis plays an important role in the survival of lambs exposed to low air temperatures. The liver produces and mediates heat production in mammals; however, to date, little is known about the role of liver genes in cold-induced ...
Dan Jiao   +8 more
doaj   +1 more source

AMPK in the Ventromedial Nucleus of the Hypothalamus: A Key Regulator for Thermogenesis

open access: yesFrontiers in Endocrinology, 2020
Obesity has become a global health issue, but effective therapies remain very limited. Adaptive thermogenesis promotes weight loss by dissipating energy in the form of heat, thereby representing a promising target to counteract obesity.
Hailan Liu   +4 more
doaj   +1 more source

Stimulatory, but not anxiogenic, doses of caffeine act centrally to activate interscapular brown adipose tissue thermogenesis in anesthetized male rats

open access: yesScientific Reports, 2021
The role of central orexin in the sympathetic control of interscapular brown adipose tissue (iBAT) thermogenesis has been established in rodents. Stimulatory doses of caffeine activate orexin positive neurons in the lateral hypothalamus, a region of the ...
L. Van Schaik   +7 more
doaj   +1 more source

Thermogenesis in Birds

open access: yesBioscience Reports, 2001
The article discusses the importance of avian skeletal muscle as a source for heat generation by means of both shivering and non-shivering. Non-shivering thermogenesis in birds is still a polemic issue. Recent evidence at the molecular/cellular level indicates, however, that this type of heat generation may also exist among birds.
J E, Bicudo   +2 more
openaire   +2 more sources

Ablation of ORMDL3 impairs adipose tissue thermogenesis and insulin sensitivity by increasing ceramide generation

open access: yesMolecular Metabolism, 2022
Objective: Genome-wide association studies identified ORMDL3 as an obesity-related gene, and its expression was negatively correlated with body mass index.
Yu Song   +11 more
doaj   +1 more source

PERAN LEMAK COKLAT DALAM MEKANISME PRODUKSI PANAS

open access: yesJurnal Berita Ilmu Keperawatan, 2008
Thermoregulation system have two process heat production, they are shivering and non shivering thermogenesis. Non shivering thermogenesis more happens in newborn human especially to adapt of low temperatures.
Siti Arifah, Kartinah Kartinah
doaj   +1 more source

At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1

open access: yesMolecular Metabolism, 2019
Objective: Hyperthyroidism is associated with increased metabolism (“thyroid thermogenesis”) and elevated body temperature, often referred to as hyperthermia.
Claudia Dittner   +3 more
doaj   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism

open access: yesChinese Medicine, 2021
Background Intermittent or prolonged exposure to severe cold stress disturbs energy homeostasis and can lead to hypothermia, heart failure, Alzheimer’s disease, and so on. As the typical “hot” traditional Chinese medicine, Aconite has been widely used to
Juan Liu   +4 more
doaj   +1 more source

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