Recent Advances in the Synthesis and Applications of 1,2,3/1,2,5-Thiadiazole- and Benzo[c][1,2,5/1,2,3]thiadiazole-Type Compounds [PDF]
MoleculesThiadiazole derivatives, such as 1,2,3-thiadiazole, 1,2,5-thiadiazole, benzo[c][1,2,5]thiadiazole, and benzo[d][1,2,3]thiadiazole, have garnered significant attention due to their exceptional chemical and physical properties.
Diego Quiroga +2 more
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Co-crystalization and in vitro biological characterization of 5-Aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors [PDF]
, 2012 A potential therapeutic strategy for targeting cancer that has gained much interest is the inhibition of the ATP binding and ATPase activity of the molecular chaperone Hsp90.
Chrisostomos Prodromou +7 more
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Synthesis, Biological and Docking Studies of Thiadiazole Amide Derivatives Containing Anthranilic Acid [PDF]
Journal of Sciences, Islamic Republic of Iran, 2023 Cancer has been become threatening the health and life of humans. Therefore, attempt to discovery more effective anticancer agents continue. Thiadiazole derivatives have been shown remarkable effects among chemotherapeutic agents.
farshid hassanzadeh +3 more
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Synthetic Transformations and Medicinal Significance of 1,2,3-Thiadiazoles Derivatives: An Update
Applied Sciences, 2021 The 1,2,3-thiadiazole moiety occupies a significant and prominent position among privileged heterocyclic templates in the field of medicine, pharmacology and pharmaceutics due to its broad spectrum of biological activities.
Ali Irfan +7 more
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Molecules, 2023 A convenient and efficient synthetic protocol for the new selenadiazole. Thiadiazole and diazaphosphole derivatives incorporating a pyridazine moiety originating from 4-(4-aminophenyl)-4-oxobutanoic acid (1) were described.
I. E. El-Shamy +4 more
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Thiadiazoles: the appropriate pharmacological scaffolds with leishmanicidal and antimalarial activities: a review [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Leishmaniasis and malaria are serious public health problems in tropical and sub-tropical regions worldwide. Development of drug-resistant strains has disrupted efforts to control the spread of these diseases in the world.
Azar Tahghighi, Fateme Babalouei
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Synthesis and Bioactivities of Novel Galactoside Derivatives Containing 1,3,4-Thiadiazole Moiety
Frontiers in Chemistry, 2022 A series of novel galactoside derivatives containing 1,3,4-thiadiazole moiety were synthesized, and the structure of them was verified by spectroscopy of NMR and HRMS, and antifungal and antibacterial activities of them were screened.
Yafei Shu +9 more
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Advanced Science, 2023 The establishment of facile synthetic routes to engineer covalent organic frameworks (COFs) with fully conjugated structure and excellent stability is highly desired for practical applications in optoelectronics and photocatalysis.
Shuailong Yang +3 more
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Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold
Chemistry, 2022 The chemistry of 1,3,4-thiadiazole is one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities.
Tulika Anthwal +2 more
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Synthesis of some Schiff's bases derivatives from aminoazo compounds
مجلة بغداد للعلوم, 2007 Reaction of,2- [( 4- amio phenyl ) diazenyl] 1,3,4- thiadiazole -5- thiol (S1) with p- chlorobenzeldehyde,3,4 – dimethoxy benzaldehyde and pyrrol-2- carbonxaldehyde gave -5- [{4-(4-chlorobenzylidene amino) phenyl} diezenyl]-1,3,4- thiadiazole-2- thiol ...
Baghdad Science Journal
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