Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry [PDF]
Modern combinatorial chemistry is used to discover compounds with desired function by an alternative strategy, in which the biological target is directly involved in the choice of ligands assembled from a pool of smaller fragments. Herein, we present the
Anna Lucia Fallacara +11 more
core +1 more source
A Three-Component Approach to 3,5-Diaryl-1,2,4-thiadiazoles under Transition-Metal-Free Conditions.
A novel route is disclosed for the synthesis of 1,2,4-thiadiazoles starting from amidines, elemental sulfur, and 2-methylquinolines or aldehydes under transition-metal-free conditions. This three-component approach affords efficient and rapid access to 3,
H. Xie +4 more
semanticscholar +1 more source
Toward the 3rd Generation of Smart Farming: Materials, Devices, and Systems for E‐Plant Technologies
This review explores the latest developments in e‐plant technologies, which are revolutionizing smart farming by enabling real‐time monitoring of plant and environmental conditions. It covers the design, applications, and systems of e‐plant devices, detailing how they integrate data analytics to optimize agricultural practices, enhance crop yields, and
Daegun Kim +5 more
wiley +1 more source
Microwave-assisted synthesis of some novel compounds, namely, 3-(2-methyl-1H-indol-3-yl)-6-aryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles 5a,b was accomplished via bromination of 2-methyl-3-[4-(arylideneamino)-5-mercapto-4H-[1,2,4]triazol-3-yl]-1H ...
Sobhi M. Gomha, Sayed M. Riyadh
doaj +1 more source
Analgesic Activity of Some 1,2,4-Triazole Heterocycles Clubbed with Pyrazole, Tetrazole, Isoxazole and Pyrimidine [PDF]
Purpose: In the present study in vivo analgesic activity of some previously synthesized 1,2,4-triazole derivatives containing pyrazole, tetrazole, isoxazole and pyrimidine ring have been evaluated.
Appala Raju +3 more
core +1 more source
Design of Terpene‐Based Eco‐Friendly Solution Process for High‐Performance Organic Solar Cells
High‐performance, terpene‐processed organic solar cells (OSCs) by designing a new green co‐solvent system consisting of eucalyptol (Eu) and 2‐methyltetrahydrofuran (MeTHF) are developed. The OSCs processed from the optimal ratio of Eu and MeTHF achieve the highest power conversion efficiency (PCE) value of 17.3% reported to date for terpene‐processed ...
Hyerin Jeon +3 more
wiley +1 more source
A novel proquinoid‐type electron acceptor, TQC‐4Cl, with an ultra‐narrow bandgap of 1.01 eV and spectral response beyond 1200 nm enables organic SWIR photodetectors. The optimized devices show a high EQE of 13.66% and high specific detectivity over 1012 Jones at 1200 nm under −0.5 V reverse bias with outstanding thermal stability, highlighting their ...
Yeonsu Choi +12 more
wiley +1 more source
3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity [PDF]
A new series of nortopsentin analogues, in which the imidazole ring of the natural product was replaced by thiazole and the indole unit bound to position 2 of the thiazole ring was substituted by a 7-azaindole moiety, was efficiently synthesized.
Attanzio, A. +11 more
core +2 more sources
Bioactive Azoles with Three Heteroatoms [PDF]
This issue is dedicated to scientists belonging to either or both the fields of heterocyclic and medicinal chemistry. Nowadays, pharmaceutical industries are more and more dedicating their research towards different use or applications of the same ...
PACE, A
core
Pharmacological and Structure-Activity Relationship Evaluation of 4-aryl-1-Diphenylacetyl(thio)semicarbazides [PDF]
This article describes the synthesis of six 4-aryl-(thio)semicarbazides (series a and b) linked with diphenylacetyl moiety along with their pharmacological evaluation on the central nervous system in mice and computational studies, including ...
Fidecka, Sylwia +8 more
core +2 more sources

