Results 81 to 90 of about 4,593 (180)
Smart Molecules, EarlyView.A smart design strategy for NIR‐II organic fluorophores is proposed by combining self‐driven Iterative evolution, deep Learning, and fragment‐based assembly. This work establishes a broadly applicable approach for molecular design, accelerating the discovery of NIR‐II fluorophores and extending to optoelectronic materials and therapeutic compounds ...
Yu Zhang +6 more
wiley +1 more source
Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova +3 more
wiley +1 more source
We report a method for using elemental sulfur to facilitate the cyclization of aryl hydrazones and aryl isothiocyanates, affording biorelated 2-imino-1,3,4-thiadiazoles.
Anh T. Nguyen (7865891) +4 more
core +1 more source
[O─I─O]+ Halogen‐Bonded Complexes of Pyridine N‐Oxides
Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.The missing puzzle of 3‐center‐4‐electron halogen‐bonded complexes viz. [O─I─O]+ of pyridine N‐oxides are structurally characterized by x‐ray diffraction. Monodentate N‐oxide O‐atom acts as the halogen bond acceptor. Their solution complexations are characterized by 15N NMR spectroscopy.
Rakesh Puttreddy +3 more
wiley +2 more sources
Mass spectral studies of 3,5-Diamino-1,2,4-thiadiazoles
, 1977 The mass spectra and fragmentation mechanisms of some 5-alkyl(or aryl)amino-3-amino-, 5-amino-3- arylamino-, 3,5-bis(arylamino)-, 4- aryl-3-arylamino-5-imino-4,5-dihydro-, and 3-alkyl(or aryl)amino-4- aryl-5-arylimino-4,5-dihydro-1,2,4-thiadiazoles and ...
KN Rajasekharan, CP Joshua
core +1 more source
The efficient synthesis of γ-thiapyrones by a base-mediated Diels–Alder/retro-Diels–Alder reaction of α-pyrones with 5-H-1,2,3-thiadiazoles is reported herein.
Bin Huang (331329) +3 more
core +1 more source
, 1967 Several 2-substituted-5-mercapto-1,3,4-thiadiazoles have been synthesised. Their sodium salts have been condensed with appropriate alkyl and aralkyl halides and the resultant sulphides oxidised to corresponding sulphones.
S. Giri, H. Singh
core +1 more source
Optical Detection of Cellular Signals at Material Interfaces
Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
, 2020 A new synthetic approach to 1,2,4-thiadiazoles using tetra(n-butyl)ammonium peroxydisulfate via oxidative dimerization of thioamides is described. This new oxidative protocol is simple, highly efficient, and allows the practical synthesis of 1,2,4 ...
Yong Hae Kim (2676469) +2 more
core +1 more source
Recent Advances in the Denitrogenative Annulation Reactions of 1,2,3-Thiadiazoles
1,2,3-Thiadiazoles exhibit versatile reactivity due to their ability to undergo ring cleavage, forming α-diazothione species through a Dimroth-type equilibrium.
Sinead T Keaveney (20250621) +2 more
core +1 more source