Results 71 to 80 of about 4,281 (225)

Rh(I)-catalyzed enantioselective (3 + 2) transannulations of 1,2,3-thiadiazoles with P-chiral monodentate phosphines

, 2023
As a proof of concept, P-chiral monodentate phosphines, which were inactive in promoting the transannulations of 1,2,3-thiadiazoles, were proven viable in the asymmetric catalytic (3 + 2) transannulations of 1,2,3-thiadiazoles with a strained bicyclic ...
Cunzhi Chen (12230874), Zhanhui Yang (1626880), Hao Wei (1649206), Aijun Gao (9277247)   +3 more
core   +1 more source

Physical-chemical properties of 5-(3-fluorophenyl)-4-amino-1,2,4-triazole-3-thiol s-derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Introduction. Currently an attempt to combine 1,2,4-triazole heterocycle with various pharmacologically active fragments of other organic molecules is popular among the scientists.
O. A. Bihdan, V. V. Parchenko
doaj   +1 more source

A Nano-MgO and Ionic Liquid-Catalyzed 'Green' Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51). [PDF]

PLoS ONE, 2015
In this work, we describe the 'green' synthesis of novel 6-(adamantan-1-yl)-2-substituted-imidazo[2,1-b][1,3,4]thiadiazoles (AITs) by ring formation reactions using 1-(adamantan-1-yl)-2-bromoethanone and 5-alkyl/aryl-2-amino1,3,4-thiadiazoles on a nano ...
Sebastian Anusha, Baburajeev Cp, Chakrabhavi Dhananjaya Mohan, Jessin Mathai, Shobith Rangappa, Surender Mohan, Chandra, Shardul Paricharak, Lewis Mervin, Julian E Fuchs, Mahedra M, Andreas Bender, Basappa, Kanchugarakoppal S Rangappa   +13 more
doaj   +1 more source

Design Principles for Next Generation of Small Organic Molecules for Photodynamics Therapy Revealed by Nonadiabatic Molecular Dynamics

Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
Molecular design reshapes the landscape of excited‐state relaxation. Nonadiabatic dynamics reveal how electronic structure guides population flow between competing pathways beyond static energetic arguments. ABSTRACT Nitrobenzochalcogenadiazole derivatives are emerging candidates for photodynamic therapy (PDT), yet the precise mechanisms governing ...
Vinícius N. da Rocha, Davide Avagliano, Paulo C. Piquini   +2 more
wiley   +1 more source

Elemental Sulfur Promoted Cyclization of Aryl Hydrazones and Aryl Isothiocyanates Yielding 2‑Imino-1,3,4-thiadiazoles

We report a method for using elemental sulfur to facilitate the cyclization of aryl hydrazones and aryl isothiocyanates, affording biorelated 2-imino-1,3,4-thiadiazoles.
Anh T. Nguyen (7865891), Phuong T. Dinh (8698236), Tan N. Huynh (17935204), Khanh T. N. Ong (17935207), Tung T. Nguyen (7535555)   +4 more
core   +1 more source

Development of novel triazolo-thiadiazoles from heterogeneous "green" catalysis as protein tyrosine phosphatase 1B inhibitors [PDF]

, 2015
Condensed-bicyclic triazolo-thiadiazoles were synthesized via an efficient "green" catalyst strategy and identified as effective inhibitors of PTP1B in vitro.
Ali Alharbi, S., Girish, K.S., Sethi, G, Zayed, M. E., Dhananjaya Mohan, C, Sivaraman Siveen, K, Alharbi, S. A., Chinnathambi, A, Baburajeev, C.P., Li, F, Ananda, H., Baburajeev, C. P., Ali Alharbi, S, Sivaraman Siveen, K., Jagadish, S., Rangappa, K.S., Rangappa, K.S, Chinnathambi, A., Sethi, G., Bender, A., Siveen, K. S., Bender, A, Dhananjaya Mohan, C., Fuchs, J. E., Rangappa, K. S., Zhang, J., Jagadish, S, Fuchs, J.E, Mohan, C. D., Rangappa, S., Girish, K.S, Girish, K. S., Fuchs, J.E., Li, F., Basappa, Zayed, M.E., Basappaa, ., Baburajeev, C.P, Zayed, M.E, Ananda, H, Rangappa, S, Zhang, J   +41 more
core   +1 more source

Synthesis and Evaluation of the Anti-Microbial Activity of New Heterocycles Containing the 1,3,4-Thiadiazole Moiety

Molecules, 2011
A new series of thiadiazole-enaminones 4 were synthesized via reactions of 5-acetyl-1,3,4-thiadiazoles 3 with dimethylformamide-dimethylacetal (DMF-DMA).
Thoraya A. Farghaly, Zienab A. Muhammad, Magda A. Abdallah   +2 more
doaj   +1 more source

Iodine‐Mediated Electrochemical Diastereoselective Synthesis of Enaminones

ChemElectroChem, Volume 13, Issue 12, 17 June 2026.
This work describes an efficient electrochemical (EC) method for transforming thioamides into enaminones via reaction with organic diazo compounds. The electrochemical approach is cost‐effective, mild, and proceeds through the in situ electrochemical generation of a copper complex.
Ijaz Khan, Głowacki Michał P., Rybicka‐Jasińska Katarzyna   +2 more
wiley   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Synthesis of γ‑Thiapyrones by Diels–Alder/Retro-Diels–Alder Reaction of α‑Pyrones with 5‑H‑1,2,3-Thiadiazoles

The efficient synthesis of γ-thiapyrones by a base-mediated Diels–Alder/retro-Diels–Alder reaction of α-pyrones with 5-H-1,2,3-thiadiazoles is reported herein.
Bin Huang (331329), Liangbin Huang (1687894), Mengxia Feng (18269197), Huanfeng Jiang (1392913)   +3 more
core   +1 more source