Results 11 to 20 of about 4,281 (225)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017 Nowadays an attempt to create a number of new biologically active compounds by many scientific groups is being one of the topical issues in the domestic pharmaceutical industry.
O. A. Bihdan, V. V. Parchenko
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Synthesis and Diuretic Activity of Substituted 1,3,4-Thiadiazoles
Scientifica, 2022 1,3,4-Thiadiazole nuclease, a 5-membered heterocyclic ring system containing two nitrogen and one sulfur atoms in addition to carbon atoms, is compound that showed promising results in the process of searching new diuretic agents. In this study, seven 5-
Asrat Ergena +2 more
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Synthesis and Screening of Substituted Thiadiazoles Against Gleophyllum Straitum [PDF]
E-Journal of Chemistry, 2004 Cyclocondensation of a series of substituted phenoxy methylene carboxylic acids with thiosemoicarbazides afforded 2-Amino-5-Aryloxy Methylene –1,3,4 Thiadiazoles (Ia-Ie).
M. G. H. Zaidi +2 more
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Comparison of HPLC, HPTLC, and In Silico Lipophilicity Parameters Determined for 5-Heterocyclic 2-(2,4-Dihydroxyphenyl)-1,3,4-thiadiazoles [PDF]
MoleculesThe 5-heterocyclic 2-(2,4-dihydroxyphenyl)-1,3,4-thiadiazoles were obtained as potential biologically active compounds. Lipophilicity is one of the most important physicochemical properties of compounds and was already taken into account during the drug ...
Beata Paw +5 more
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Chemoselective synthesis of 1,3,4-thiadiazoles from acyl hydrazines and nitroalkanes using elemental sulfur [PDF]
Nature CommunicationsSubstituted 1,3,4-thiadiazoles find extensive use in pharmaceutical, agricultural, and materials chemistry. The incorporation of adaptable heterocyclic pharmacophores results in tunable hybrid molecules with diverse medicinal properties.
Xiaonan Wang +6 more
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Croatica Chemica Acta, 1971 New derivatives of 1,3,4-thiadiazoles with potential phytohormonic (compds. I-V) and antibacterial (compds. VI-IX) activity have been prepared. Mesoionic structure of the compounds VI- IX is indicated by their IR and UV spectra.
Kuftinec, J., Kolbah, D.
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Development of Rh(I)-catalyzed denitrogenative transformations of 1,2,3-thiadiazoles
, 2023 Presented herein are a series of studies designed to increase the fundamental understanding, and expand the application in heterocyclic synthesis, of the Rh(I)-catalyzed denitrogenative transformations of 1,2,3-thiadiazoles − a new class of reactions ...
Marina A. Tokareva (17255824)
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Molecules, 2023 A large variety of 1,2,3-thiadiazoles and 1,2,3-triazoles are used extensively in modern pure and applied organic chemistry as important structural blocks of numerous valuable products.
Dmitrii M. Mazur +6 more
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3-Phenoxymethyl-6-phenyl-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
IUCrData, 2016 In the title compound, C16H12N4OS, the bicyclic triazolothiadiazole core is approximately planar, with an r.m.s. deviation of 0.018 Å. The phenyl rings are inclined to its mean plane by 7.66 (7) and 71.79 (7)°.
Shaaban K. Mohamed +4 more
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Synthesis of 2- alkyl/phenyl -5-Substituted 1,3,4- Thiadiazoles [PDF]
مجلة التربية والعلم, 2014 In this paper the synthesis of some 2-alkyl phenyl 5-substituted 1,3,4-thiadiazole is reported, Benzonitrile and Acetonitrile were treated with thiosemicarbazide in presence of trifluroacetic acid to give 2-alkyl/ aryl -5- amino- 1,3,4- thiadiazoles (1,2)
Khalid Daoud +2 more
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