Results 21 to 30 of about 4,281 (225)

Direct Exchange of Oxygen and Selenium Atoms in the 1,2,5-Oxadiazoles and 1,2,5-Selenadiazoles by Action of Sulfur Monochloride

Molecules, 2015
A short synthetic approach to fused 1,2,5-thiadiazoles from the corresponding 1,2,5-oxadiazoles and 1,2,5-selenadiazoles has been developed. Mono- and bis(1,2,5-thiadiazoles) were selectively obtained in high yields.
Lidia S. Konstantinova, Ekaterina A. Knyazeva, Oleg A. Rakitin   +2 more
doaj   +1 more source

Visible-light-induced intramolecular C–S bond formation for practical synthesis of 2,5-disubstituted 1,3,4-thiadiazoles

, 2022
A general and facile visible-light mediated protocol for the synthesis of 2-arylamino-5-aryl-1,3,4- thiadiazoles via one-pot condensation and intramolecular C–S coupling cascade reaction has been developed.
Ruohan Li (6490004), Shouri Sheng (2880404), Haishan Wei (14195173), Junmin Chen (625300), Wenqing Lan (14195170), Zhaocheng Shi (14195167)   +5 more
core   +1 more source

Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors

Molecules, 2022
The present study aims to discover novel derivatives as antiapoptotic agents and their protective effects against renal ischemia/reperfusion. Therefore, a series of new thiadiazole analogues 2a–g was designed and synthesized through cyclization of the ...
Sara M. Mostafa, Ashraf A. Aly, Stefan Bräse, Martin Nieger, Sara Mohamed Naguib Abdelhafez, Walaa Yehia Abdelzaher, El-Shimaa M. N. Abdelhafez   +6 more
doaj   +1 more source

Chitosan-MgO Nanocomposite: One Pot Preparation and Its Utility as an Ecofriendly Biocatalyst in the Synthesis of Thiazoles and [1,3,4]thiadiazoles

Nanomaterials, 2018
A chitosan-MgO hybrid nanocomposite was prepared using a simple chemical precipitation method and characterized using Fourier transform spectroscopy (FTIR), elemental analysis (EDX), and scanning electron microscopy (SEM). The nanocomposite was served as
Sayed M. Riyadh, Khaled D. Khalil, Ateyatallah Aljuhani   +2 more
doaj   +1 more source

Synthesis of Novel Triazoles, Tetrazine, Thiadiazoles and Their Biological Activities

Molecules, 2015
An expedient synthesis of novel triazoles, tetrazine and thiadiazoles, using conveniently accessible and commercially available starting materials has been achieved.
Mohammed A. Al-Omair, Abdelwahed R. Sayed, Magdy M. Youssef   +2 more
doaj   +1 more source

Electrochemical Synthesis of 1,2,3-Thiadiazoles from Phenylhydrazones

, 2021
We have developed an electrochemical approach for the synthesis of fully substituted 1,2,3-thiadiazoles from α-phenylhydrazones at room temperature, which is very challenging and complementary to the conventional thermal reactions.
Pragya Pali (9143670), Priya Saha, Priya Saha (10750110), Maya Shankar Singh, Gaurav Shukla, Maya Shankar Singh (1725268), Pragya Pali, Keshav Raghuvanshi, Keshav Raghuvanshi (1939177), Gaurav Shukla (2105080)   +9 more
core   +1 more source

Electrochemical Oxidative Intramolecular N–S Bond Formation: Synthesis of 3‑Substituted 5‑Amino-1,2,4-Thiadiazoles

, 2020
A facile and efficient protocol for the synthesis of 3-substituted 5-amino-1,2,4-thiadiazoles has been developed through the electro-oxidative intramolecular dehydrogenative N–S bond formation of imidoyl thioureas.
Kun Liu, Kun Liu (148201), Jiaqi Zhang (412762), Tao Yang, Lijun Li (406691), Liping Hu, Liping Hu (172765), Zan Yang, Congshan Zhou, Congshan Zhou (1923325), Zan Yang (5513243), Jiaqi Zhang, Tao Yang (184280), Lijun Li   +13 more
core   +1 more source

Comparative Study of the Synthetic Approaches and Biological Activities of the Bioisosteres of 1,3,4-Oxadiazoles and 1,3,4-Thiadiazoles over the Past Decade

Molecules, 2022
The bioisosteres of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles are well-known pharmacophores for many medicinally important drugs. Throughout the past 10 years, 1,3,4-oxa-/thiadiazole nuclei have been very attractive to researchers for drug design ...
Rana M. El-Masry, Hanan H. Kadry, Azza T. Taher, Sahar M. Abou-Seri   +3 more
doaj   +1 more source

Mechanistic Insight Into the Polymorph‐Dependent Photosalient Effect of a White Light or Two‐Photon Activated Photoreactive Molecular Salt

Angewandte Chemie, EarlyView.
Photocycloaddition in stilbene‐type salt polymorphs exhibit distinct light‐driven responses: OHT‐TI shows a violent photosalient effect under visible and NIR (two‐photon) irradiation, whereas OHT‐TII reacts statically. Packing and computational analysis reveals that shell‐like structures in OHT‐TI frustrate structural relaxation, accumulating explosive
Emanuela Santagata, Francesco Ambrosio, Amedeo Capobianco, Andrea Peluso, Giorgia Rizzi, Stijn Van Cleuvenbergen, Yovan de Coene, Koen Clays, Paolo Pio Mazzeo, Roberto Centore, Fabio Borbone   +10 more
wiley   +2 more sources

Biological activities of imidazo[2,1-b][1,3,4]thiadiazole derivatives: A review

Journal of Saudi Chemical Society, 2016
Imidazo[2,1-b][1,3,4]thiadiazole heterocycle was discovered during the 1950s. Since then, many newer derivatives are being developed and evaluated for their biological profiles. The derivatives of imidazo[2,1-b][1,3,4]thiadiazoles are widely explored for
Bhoomendra A. Bhongade, Sirajunisa Talath, Ravikiran A. Gadad, Andanappa K. Gadad   +3 more
doaj   +1 more source