Results 151 to 160 of about 59,616 (308)

Water Networks as Hydrophobic Recognition Motifs in Proteins

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Hydrophobic groups can strengthen confined water networks, promoting order that propagates through the protein structure and drives recognition, creating a paradoxical hydrophobic binding hot spot. Polar groups are rejected because they disrupt the network, destabilizing the protein structure.
Serena G. Piticchio, Miriam Martínez‐Cartró, Salvatore Scaffidi, Sergio Rodríguez‐Arévalo, Andrea Bagán, Ainoa Sánchez‐Arfelis, Sarah Picaud, Tobias Krojer, Panagis Filippakopoulos, Frank von Delft, Carmen Escolano, Carles Galdeano, Xavier Barril   +12 more
wiley   +2 more sources

SYNTHESIS AND ANTIBACTERIAL PROPERTIES OF N,N-DISUBSTITUTED β-AMINO ACIDS CONTAINING FUNCTIONALIZED THIAZOLE FRAGMENT IN THE STRUCTURE

, 2017
Eglė Urbonavičiūtė, Rita Vaickelionienė, Giedrius Vaickelionis, Vytautas Mickevičius   +3 more
openalex   +2 more sources

Green Construction of Aryl-1,8-Naphthyridine-Thiazole Scaffolds and in Vitro-Antimicrobial Evaluation, Dna-Binding Interactions, Viscosity Measurements, Molecular Modeling Studies, and Adme Properties

, 2023
B. Sonyanaik, Dharavath Ravi, Kamal Kishore, Perugu Shyam, B. Sakram   +4 more
openalex   +1 more source

Pseudotetraivprolides from Pseudomonas entomophila Provide Insights into the Biosynthesis of Detoxin/Rimosamide‐Like Anti‐Antibiotics

Angewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.
Pseudotetraivprolide is a new player among the Detoxin/Rimosamide‐like natural products! Its biosynthesis requires FabD from primary metabolism and a PipDFG complex for final‐step acetylation – unlocking its anti‐antibotic activity. Abstract Novel variants of known natural product (NP) classes can provide valuable insights into their biosynthesis ...
Edna Bode, Julia Büllesbach, Kevin Bauer, Yan‐Ni Shi, Simon Reiners, Ziheng Cui, Petra Happel, Yi‐Ming Shi, Kevin Hoffmann, Peter Grün, Bianca Pommerenke, Uli Kazmaier, Martin Grininger, Helge B. Bode   +13 more
wiley   +1 more source

Synthetic Study of Dolastatin 3 Bearing Thiazole Ring

, 1984
Yasumasa Hamada, Michiko Kokutyu, Takayuki Shioiri   +2 more
openalex   +1 more source

Synthesis, spectroscopic characterization, crystal structure and antifungal activity of thiourea derivatives containing a thiazole moiety [PDF]

, 2010
Sohail Saeed, Naghmana Rashid, Peter G. Jones, Rizwan Hussain, Moazzam H. Bhatti   +4 more
openalex   +1 more source

(1S,3′S,3a′R,6′S)-6′-(2-Chlorophenyl)-3′-[(2R,3S)-1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2-yl]-2-oxo-3′,3′a,4′,6′-tetrahydro-2H,2′H-spiro[acenaphthylene-1,1′-pyrrolo[1,2-c][1,3]thiazole]-2′,2′-dicarbonitrile

, 2013
Seenivasan Karthiga Devi, T. Srinivasan, R. Ramesh Raju, R. Raghunathan, D. Velmurugan   +4 more
openalex   +1 more source

Recent Advances in Homogeneous Catalysis with Platinum Group Pincer Complexes: Hydrogen‐Mediated Transformations and Cross‐Coupling Reactions

The Chemical Record, Volume 26, Issue 1, January 10, 2026.
Platinum group pincer complexes are highly efficient catalysts. Additionally, their high activity enables challenging transformations with low catalyst loading. Herein, we summarize the most relevant advances of catalysis involving platinum group pincer complexes. The use of pincer complexes based on platinum group metals is undoubtedly one of the most
Juan S. Serrano‐García, Andrés Amaya‐Flórez, Jordi R.‐Galindo, Adrián Ruíz‐Martínez, David Morales‐Morales   +4 more
wiley   +1 more source

Thiazole Effect on Phycomyces [PDF]

Proceedings of the National Academy of Sciences, 1941
W J, Robbins, F, Kavanagh
openaire   +2 more sources

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

, 2015
Tihomir Tomašič, Sotirios Katsamakas, Žiga Hodnik, Janez Ilaš, Matjaž Brvar, Tom Šolmajer, Sofía Montalvão, Päivi Tammela, Mihailo Banjanac, Gabrijela Ergović, Marko Anderluh, Lucíja Peterlin Mašič, D. Kikelj   +12 more
openalex   +1 more source