Optimizing Odorants for Olfactory Training Based on Olfactory Receptor–Ligand Pair Analysis
This study employs receptor–ligand interaction analysis and olfactory epithelium transcriptomics to optimize olfactory training (OT). A novel four‐odorant combination (galaxolide, eugenol acetate, [−]‐menthol, geranyl acetate) activates 83.9% of 385 human olfactory receptors (ORs), covering 69.9% of estimated OR expression—significantly outperforming ...
Hironobu Nishijima +7 more
wiley +1 more source
Repurposed Arylidene-hydrazinyl-1,3-thiazoles as Multitarget Anti-Alzheimer's Agents via Combined Computational and Experimental Studies. [PDF]
Drozdowska D +7 more
europepmc +1 more source
Electrochemical regioselective trifluoromethylation of imidazo[2,1-b]thiazoles with CF3SO2Na
Liu, Meilin +3 more
openalex +1 more source
New Aryl-1,3-thiazole-4-carbohydrazides, Their 1,3,4-Oxadiazole-2- thione, 1,2,4-Triazole, Isatin-3-ylidene and Carboxamide Derivatives. Synthesis and Anti-HIV Activity [PDF]
Mehwash Zia +3 more
openalex +1 more source
Colorimetric Detection of Nickel Ions Using Bacterial Nanocellulose Paper‐Based Strips
Bacterial nanocellulose membranes exhibit interesting physicochemical properties, including large surface area, high porosity, mechanical strength, and a rich hydroxyl surface. Their synergistic combination with the chromogenic agent 4‐(2‐thiazolylazo)resorcinol enabled the development of a simple and affordable paper‐based colorimetric sensor, which ...
Admilton A. P. Santana +6 more
wiley +1 more source
Optimized Synthesis of Novel Pyrazole Based Thiazole Derivatives and their Antimicrobial Evaluation [PDF]
Nisheeth C. Desai, Malay J. Bhatt
openalex +1 more source
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca +2 more
wiley +1 more source
Synthesis and Biological Assessment of New Thiazoles for Mycobacterial Infections and Biofilm Disruption. [PDF]
Folquitto LRDS +11 more
europepmc +1 more source
Eugenol‐Based Thiazole Derivatives Inhibit the MepA Efflux Pump in Staphylcoccus aureus
ABSTRACT Multidrug resistant (MDR) bacteria are considered critical priority pathogens by the World Health Organization (WHO). Considering the relevance of antibacterial drug development in this scenario, the present research study aimed to evaluate the antibacterial activity of eugenol‐based thiazole derivatives and analyze their potential to inhibit ...
Ray Silva de Almeida +13 more
wiley +1 more source

