Results 191 to 200 of about 59,616 (308)

Optimizing Odorants for Olfactory Training Based on Olfactory Receptor–Ligand Pair Analysis

open access: yesThe Laryngoscope, Volume 136, Issue 1, Page 384-394, January 2026.
This study employs receptor–ligand interaction analysis and olfactory epithelium transcriptomics to optimize olfactory training (OT). A novel four‐odorant combination (galaxolide, eugenol acetate, [−]‐menthol, geranyl acetate) activates 83.9% of 385 human olfactory receptors (ORs), covering 69.9% of estimated OR expression—significantly outperforming ...
Hironobu Nishijima   +7 more
wiley   +1 more source

Repurposed Arylidene-hydrazinyl-1,3-thiazoles as Multitarget Anti-Alzheimer's Agents via Combined Computational and Experimental Studies. [PDF]

open access: yesACS Omega
Drozdowska D   +7 more
europepmc   +1 more source

Colorimetric Detection of Nickel Ions Using Bacterial Nanocellulose Paper‐Based Strips

open access: yesMacromolecular Materials and Engineering, Volume 311, Issue 1, January 2026.
Bacterial nanocellulose membranes exhibit interesting physicochemical properties, including large surface area, high porosity, mechanical strength, and a rich hydroxyl surface. Their synergistic combination with the chromogenic agent 4‐(2‐thiazolylazo)resorcinol enabled the development of a simple and affordable paper‐based colorimetric sensor, which ...
Admilton A. P. Santana   +6 more
wiley   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca   +2 more
wiley   +1 more source

Synthesis and Biological Assessment of New Thiazoles for Mycobacterial Infections and Biofilm Disruption. [PDF]

open access: yesACS Omega
Folquitto LRDS   +11 more
europepmc   +1 more source

Eugenol‐Based Thiazole Derivatives Inhibit the MepA Efflux Pump in Staphylcoccus aureus

open access: yesChemistrySelect, Volume 11, Issue 3, 22 January 2026.
ABSTRACT Multidrug resistant (MDR) bacteria are considered critical priority pathogens by the World Health Organization (WHO). Considering the relevance of antibacterial drug development in this scenario, the present research study aimed to evaluate the antibacterial activity of eugenol‐based thiazole derivatives and analyze their potential to inhibit ...
Ray Silva de Almeida   +13 more
wiley   +1 more source

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