Results 281 to 290 of about 45,916 (341)

Visible-Light-DrivenOne-Pot Synthesis of Polycyclic-FusedAmino-Thiazoles and Amino-Selenazoles via HFIP-Promoted MulticomponentCyclizations

Nurabul Mondal (16495910), Sunidhi Raj (22397663), Lokman H. Choudhury (2410642)   +2 more
openalex   +1 more source

Novel thiazole derivatives as effective anti-cancer agents against human osteosarcoma cell line (SaOS-2): Microwave-assisted one-pot three-component synthesis, in vitro anti-cancer studies, and in silico investigations. [PDF]

PLoS One
Mermer A, Tahmasebifar A, Al-Hussain SA, Yılmaz GT, Turgut ZD, Mushtaq A, Zahoor AF, Irfan A, Zaki MEA.   +8 more
europepmc   +1 more source

Thiazole peptidomimetics as chemical modulators of <i>KRAS</i> gene expression <i>via</i> G-quadruplex stabilization. [PDF]

RSC Chem Biol
Biswas D, Gorai A, Maiti S, Chaudhuri R, Pradhan S, Dash J.   +5 more
europepmc   +1 more source

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Recent Advancements in Strategies for the Synthesis of Imidazoles, Thiazoles, Oxazoles, and Benzimidazoles

ChemistrySelect, 2023
Nitrogen‐containing heterocycles such as imidazoles, thiazoles, and oxazoles play a significant role in the fields of biological and pharmaceutical chemistry.
Kamal Kant, Chandresh K. Patel, Sourav Banerjee, Priyadarshini Naik, A. Atta, Arup K. Kabi, C. Malakar   +6 more
semanticscholar   +1 more source

Identification of Unique Quinazolone Thiazoles as Novel Structural Scaffolds for Potential Gram-Negative Bacterial Conquerors.

Journal of Medicinal Chemistry, 2021
A class of quinazolone thiazoles was identified as new structural scaffolds for potential antibacterial conquerors to tackle dreadful resistance. Some prepared compounds exhibited favorable bacteriostatic efficiencies on tested bacteria, and the most ...
Jie Wang, M. Ansari, Cheng‐He Zhou
semanticscholar   +1 more source

Recent Development in the Synthesis of Thiazoles.

Current Organic Synthesis, 2022
BACKGROUND Thiazole-containing compounds are widely found in natural products as well as synthetic sources. Many thiazole-based compounds possess a broad spectrum of bioactivities and some of them are well-known drugs in the markets.
D. Duc, Nguyen Thi Chung
semanticscholar   +1 more source

Visible-Light-Promoted [3 + 2] Cyclization of Chalcones with 2-Mercaptobenzimidazoles: A Protocol for the Synthesis of Imidazo[2,1-b]thiazoles.

Organic Letters, 2022
A visible-light-promoted [3 + 2] cyclization between chalcones and 2-mercaptobenzoimidazoles for the construction of diverse imidazo[2,1-b]thiazoles via an electron-donor-acceptor (EDA) complex has been developed.
Ziren Chen, Fei Xue, Yonghong Zhang, Weiwei Jin, Bin Wang, Yuanjiao Xia, Mengwei Xie, Ablimit Abdukader, Chenjiang Liu   +8 more
semanticscholar   +1 more source

A review on biological and medicinal significance of thiazoles

Phosphorus Sulfur and Silicon and the Related Elements, 2021
Thiazole, a five-membered heterocyclic compound constitutes the skeleton of various commercially marketed drug candidates and the heart-core in a diverse range of entities of biological and medicinal interest. It is a versatile and essential component of
P. M. Jadhav, S. Kantevari, A. B. Tekale, S. Bhosale, R. Pawar, S. Tekale   +5 more
semanticscholar   +1 more source

Identification of a novel antifungal backbone of naphthalimide thiazoles with synergistic potential for chemical and dynamic treatment.

Future Medicinal Chemistry, 2021
Aim: The high incidence and prevalence of fungal infections call for new antifungal drugs. This work was to develop naphthalimide thiazoles as potential antifungal agents.
Peng-Li Zhang, G. Lavanya, Yang Yu, Bo Fang, Cheng‐He Zhou   +4 more
semanticscholar   +1 more source

Single-Pot Preparation of 4-Amino-2-(het)aryl-5-Substituted Thiazoles Employing Functionalized Dithioesters as Thiocarbonyl Precursors.

Journal of Organic Chemistry, 2021
An effective, diversity oriented, one-pot reaction of 4-amino-2-(het)aryl/alkyl-5-functionalized thiazoles has been disclosed, utilizing aryl/heteroaryl/alkyl dithioesters as thiocarbonyl coupling partners in a modified Thorpe-Ziegler type cyclization ...
Anusha Avadhani, P. Iniyavan, Y. Kumar, H. Ila   +3 more
semanticscholar   +1 more source