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Synthesis and Molecular Docking of Some Novel Thiazoles and Thiadiazoles Incorporating Pyranochromene Moiety as Potent Anticancer Agents.

Mini-Reviews in Medical Chemistry, 2018
BACKGROUND Chemotherapy has become one of the methods that are being adopted to treat cancer. Coumarins, thiazoles and thiadiazoles are versatile synthetic scaffolds possessing wide spectrum of biological effects including potential anticancer activity.
Sobhi M. Gomha   +4 more
semanticscholar   +1 more source

Chemistry of the thiazoles

Proceedings of the Indian Academy of Sciences - Section A, 1953
In connection with the study of the orienting influences in the thiazole nucleus, 2-methylthiazole, 4-methylthiazole, 5-methylthiazole, 2-hydroxythiazole, 2-methoxythiazole, 5-acetamidothiazole and 5-acetamidothiazole-2-carboxylic acid have been nitrated and brominated and the results obtained have been presented.
K. Ganapathi, K. D. Kulkarni
openaire   +2 more sources

Kristallin‐flüssige Thiazole

Journal für Praktische Chemie, 1979
Liquid Crystal ThiazolesThe synthesis of 2,4‐ and 2,5‐disubstituted thiazoles is described and their melting and clearing points are investigated. The influence of the thiazole ring system on the formation of crystalline‐liquid phases is discussed.
K. Dölling, H. Schubert, Horst Zaschke
openaire   +2 more sources

Thiazoles and Benzothiazoles

2012
This chapter highlights the recent developments in the metalation of thiazoles and benzothiazoles as well as the reactions of the resulting metalated species (2000 to present). Metalation reactions consist of lithiation (including halogen dance reactions), magnesation, zincation, caldation, boronation, and silylation, while application of the metalated
openaire   +2 more sources

Imidazole, oxazole and thiazole alkaloids

Natural Product Reports, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
openaire   +4 more sources

Anti-inflammatory, Analgesic and Anti-ulcerogenic Activities of Novel bis-thiadiazoles, bis-thiazoles and bis-formazanes.

Medicinal chemistry, 2017
BACKGROUND Indane-1,3-dione, thiazole, bis-thiazole and thiadiazoles rings are very interested moieties in anti-inflammatory and analgesic drugs.
Zeinab A. Muhammad   +4 more
semanticscholar   +1 more source

Double C-S bond formation via C-H bond functionalization: synthesis of benzothiazoles and naphtho[2,1-d]thiazoles from N-substituted arylamines and elemental sulfur.

Chemical Communications, 2017
A novel, atom economic, and environmentally friendly method for the synthesis of 2-substituted benzothiazoles and 2-substituted naphtho[2,1-d]thiazoles from N-substituted arylamines and elemental sulfur has been developed under metal-free conditions. The
Xiaoming Zhu   +5 more
semanticscholar   +1 more source

Dimerization of Phenylalanine: An Approach to Thiazoles and Oxazoles Involved S/O‐Insertion

, 2018
We herein describe the development of a dimerization procedure for amino acids to prepare 2,5-disubstituted thiazoles and oxazoles in the presence of Na2S⋅9H2O and H2O, respectively.
Yan Cheng   +8 more
semanticscholar   +1 more source

Mesomorphic Thiazole Derivatives.

ChemInform, 2001
AbstractFor Abstract see ChemInform Abstract in Full Text.
M. M. Murza, M. G. Safarov
openaire   +2 more sources

Synthesis of Imidazo[2,1-b]thiazoles via Copper-Catalyzed A3-Coupling in Batch and Continuous Flow.

Journal of Organic Chemistry, 2017
A straightforward method for the synthesis of functionalized imidazo[2,1-b]thiazoles starting from benzaldehydes, 2-aminothiazoles, and alkynes under copper(I,II) catalysis was developed.
I. Rassokhina   +7 more
semanticscholar   +1 more source

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