Results 21 to 30 of about 319 (90)

A 2 PHASE ELECTROCHEMICAL METHOD FOR THIOCYANATION

, 1992
A two phase electrochemical method for thiocyanation has been described. Thiocyano derivatives of aromatic amines and phenols and isothiocyano derivatives of substituted amines were obtained in 50-80 ...
KRISHNAN, P, GURJAR, VG
core   +1 more source

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

Journal of the Chinese Chemical Society, Volume 73, Issue 9, Page 1278-1290, September 2026.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Regioselective Thiocyanation of Aromatic and Heteroaromatic Compounds by Using Boron Sulfonic Acid as a New, Efficient, and Cheap Catalyst in Water

Journal of Chemistry, 2013
Highly efficient regioselective thiocyanations of indoles and N,N-disubstituted anilines are achieved via a green and simple protocol using boron sulfonic acid (BSA) as a new catalyst and KSCN/H2O2 as a mild and environmentally friendly oxidant in ...
Sami Sajjadifar, Omid Louie
doaj   +1 more source

Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis

ChemistryOpen, Volume 15, Issue 6, June 2026.
This review highlights synthetic advances (2013–2025) in intramolecular C─N bond formation for constructing the pharmaceutically relevant pyrrolidine core. The review is organized into five methodological clusters: 1) intramolecular alkene/alkyne amination; 2) tandem annulations, which involve C─N bond formation as the key step; 3) nucleophilic ...
Rasma Kroņkalne, Māris Turks
wiley   +1 more source

Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade, Tales Alexandre Costa‐Silva, Gisele Monteiro   +2 more
wiley   +1 more source

Cooperative Photometallobiocatalysis: Nonheme Fe Enzyme‐Catalyzed Enantioconvergent Radical Decarboxylative Azidation, Thiocyanation, and Isocyanation of Redox‐Active Esters

Angewandte Chemie, Volume 137, Issue 29, July 14, 2025.
Through the directed evolution of an underexploited nonheme Fe extradiol dioxygenase, we developed a unified cooperative photobiocatalytic strategy to allow for three types of enantioconvergent radical transformations, including azidation, thiocyanation, and isocyanation.
Liu‐Peng Zhao, Ken Lin, Pei‐Pei Xie, Huichong Liu, Hengye Xiang, Xin Liu, Yunlong Zhao, Peng Liu, Yang Yang   +8 more
wiley   +2 more sources

Synthesis of 4-functionalized pyrazoles via oxidative thio- or selenocyanation mediated by PhICl2 and NH4SCN/KSeCN

Beilstein Journal of Organic Chemistry
A series of 4-thio/seleno-cyanated pyrazoles was conveniently synthesized from 4-unsubstituted pyrazoles using NH4SCN/KSeCN as thio/selenocyanogen sources and PhICl2 as the hypervalent iodine oxidant.
Jialiang Wu, Haofeng Shi, Xuemin Li, Jiaxin He, Chen Zhang, Fengxia Sun, Yunfei Du   +6 more
doaj   +1 more source

TXCA‐Mediated Synthesis of Halogenated 4‐Aminocoumarins Derivatives Under Mild Conditions and In Silico Evaluation Against Alzheimer's Disease‐Related Protein Targets

ChemistrySelect, Volume 11, Issue 16, 27 April 2026.
A green and sustainable protocol for the halogenation of 4‐aminocoumarins using trihaloisocyanuric acids was developed, affording compounds with the predicted potential to inhibit protein targets associated with Alzheimer's disease. ABSTRACT A highly efficient and selective protocol for the halogenation of the C─H bond of 4‐aminocoumarin derivatives is
Maryelle A. G. de Carvalho, Vinicius C. Alves, Lara M. Flores, Carlos V. Doerner, Tácia K. Hall, Cristiani F. Bortolatto, Louis P. Sandjo, José S. S. Neto, Antonio L. Braga, Francisco F. de Assis   +9 more
wiley   +1 more source

Pd‐Catalyzed Directed Thiocyanation Reaction by C−H Bond Activation

, 2020
International audienceThe Pd-catalyzed directed thiocyanation reaction of arenes and heteroarenes by CÀHb ond activation was achieved. In the presence of an electrophilic SCN source, this original methodology offered an efficient tool to access ap anel ...
Mu‐Yi Chen, Mélissa Gao, Tatiana Besset, Chen, Mu-Yi, Philippe Jubault, Gao, Mélissa, Besset, Tatiana, Pannecoucke, Xavier, Xavier Pannecoucke, Jubault, Philippe   +9 more
core   +1 more source

Unveiling the Advances in Thiazole Chemistry: Cycloaddition Approaches, Green Synthetic Strategies, and Biological Insights for Drug Discovery

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Thiazoles are one among the interesting heterocyclic compounds that have garnered significant attention over many years. They have left an indelible mark in the field of synthetic organic and medicinal chemistry. Their insights have been tremendous in recent years for research and drug development.
Glanish Jude Martis, Santosh L. Gaonkar
wiley   +1 more source