Results 101 to 110 of about 14,774 (209)

6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy

open access: yesBMC Microbiology
Background Enterovirus 71 (EV71) is one of the major causative agents of hand, foot, and mouth disease (HFMD), and can cause severe cerebral complications and even fatality in children younger than 5 years old.
Qiao You   +9 more
doaj   +1 more source

Chronic eosinophilic leukemia with monosomy 8 in a five-year-old girl: a rare case

open access: yesThe Turkish Journal of Pediatrics, 2014
A 5-year-old girl was admitted to our hospital due to fatigue and fever lasting for six months. She had systolic murmur in the mesocardiac and apex regions and hepatosplenomegaly.
Meriç Kaymak-Cihan   +10 more
doaj  

Steps in immunosuppression for renal transplantation [PDF]

open access: yes, 1983
The authors provide a historical survey of the immunosuppressive agents that have been used to prevent allograft rejection.
Hakala, TR, Rosenthal, JT, Starzl, TE
core  

MSH6- or PMS2-deficiency causes re-replication in DT40 B cells, but it has little effect on immunoglobulin gene conversion or on repair of AID-generated uracils [PDF]

open access: yes, 2017
The mammalian antibody repertoire is shaped by somatic hypermutation (SHM) and class switch recombination (CSR) of the immunoglobulin (Ig) loci of B lymphocytes.
Campo, Vanina A.   +6 more
core  

Ultrathin Fe and Ni-layer single hydroxides as efficient drug delivery agents: A first-principles study

open access: yesResults in Physics
This study investigates the intermolecular interactions between 6-mercaptopurine (MP) and 6-thioguanine (TG) drugs with Fe- and Ni-layered single hydroxides (LSH) using DFT calculations. Hydrogenated Fe and Ni LSH show the best performance as drug agents
Hazem Abdelsalam   +5 more
doaj   +1 more source

In vivo efficacy of chitosan/interleukin-12 in controlling lung metastasis in 4T1 breast cancer model [PDF]

open access: yes, 2013
Cancer immunotherapy has emerged as a leading front in cancer treatment. In contrast to other treatment methods such as radiation and surgery, immunotherapy trains the patient\u27s body to recognize and eliminate tumors, thus preventing reoccurrence of ...
Vo, Jimmy
core   +1 more source

Cover 1 - Thioguanine Abrogated Colitis Cancer Model

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
doaj   +1 more source

Sequential group trial to determine gastrointestinal site of absorption and systemic exposure of azathioprine [PDF]

open access: yes, 2000
Azathioprine (AZA) is used in the treatment of patients with refractory inflammatory bowel disease; however, its use is limited because of systemic toxicity associated with long-term use.
Abell, Thomas   +7 more
core   +1 more source

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