Reactions with 5-Arylazo- and 5-Arylidene-4-thiohydantoin Derivatives [PDF]
, 1979 5-Arylazo-3-phenyl-4-thiohydantoins (IIa-g) have been prepared and then treated with primary aromatic amines to afford the corresponding 5-arylazo-4-arylimino-3-phenyl hydantoins (VIIa-c).
A. F. A. Shalaby +2 more
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Estudio de la reactividad de las tiohidantoinas en la adición a sistemas α,β-insaturados y naftoquinónicos. [PDF]
, 2022 Las tiohidantoinas representan una familia de compuestos con una amplia gama de propiedades biológicas, la literatura disponible para este tipo de compuestos se centra en métodos de síntesis, sin embargo, su propia reactividad no se encuentra reportada a
Enrique Alejandro Flores López +1 more
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The problem of racemization in drug discovery and tools to predict it [PDF]
, 2019 Introduction: Racemization has long been an ignored risk in drug development, probably because of a lack of convenient access to good tools for its detection and an absence of methods to predict racemization risk.
Ahmad, Hiwa O. +5 more
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On the constitution of disubstituted isothiohydantions [PDF]
, 2018 Dissertation (Ph.D.)--University of Kansas, Chemistry ...
Long, Walter Sterritt
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, 1975 Department of Chemistry, Sambalpur University, Sambalpur and Department of Chemistry, G. M. College, Sambalpur. Manuscript received 27 May 1972; accepted 4 July 1975. Several substituted benzothiazolyl thiohydantoias (I), their arylideae derivatives (II) and dibromo compounds (W) have been synthesised.
M. BEHERA, P. N. DHAL, A. NAYAK
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A New Polymorph of 2-Thiohydantoin
X-ray Structure Analysis Online, 2009 A new polymorphic crystal of the title compound, C3H4N2OS, belongs to space group P1 with cell dimensions of a = 4.0520(9)A, b = 6.550(1)A, c = 9.170(2)A, α = 100.148(4)°, β = 100.814(4)°, γ = 96.831(4)°, R1 = 0.069. Neighboring molecules are connected to form cyclic dimers via two types of hydrogen bonds, one between the thioamide groups and the other
Toshiakzu OGAWA +7 more
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New approaches to optically active 2-tert-alkyl azaaryl compounds and 5,5-disubstituted hydantoins [PDF]
, 2018 562 p.The aim of this thesis has been the development of new pronucleophiles for organocatalytic reactions,leading to 2-tert-alkyl azaaryl adducts and 5,5-disubstituted hydatoins, products that are of interest inbiological and medicinal chemistry.
Izquierdo Arruferia, Joseba
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Brønsted based catalyzed Michael additions for the production of heterocyclic compounds of biological interest [PDF]
, 2023 339 p.Introducimos dos pronucleófilos, 1H-imidazol-4(5H)-onas y pirrolo[1,2-a]pirazin-4(3H)-onas, los cuales cumplen los requerimientos para actuar eficientemente en reacciones organocatalizadas y permitir su posterior funcionalización. En el Capítulo 2,
Duñabeitia Aizpurúa, Eider
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Entwicklung von organokatalytischen Synthesen und Racemisierungsverfahren von chiralen Tetrahydrochinazolin-Thiohydantoin kondensierten Heterozyklen [PDF]
This work deals with the compound class of THQZ-thiohydantoins. The focus was on the improvement of synthetic procedures, the study of the chemical structure and physical properties as well as a comprehensive investigation of an acid-induced racemization
Mai, Christina
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IN VITRO STUDIES ON THE ANTIDIABETIC ACTIVITY OF 2-THIOHYDANTOIN USING α-amylase AND α-GLUCOSIDASE [PDF]
, 2019 Objective: The aim of the present study was to investigate the inhibitory effect of 2-thiohydantoin on the enzymes α-amylase and α-glucosidase in vitro as an antidiabetic therapeutic approach to reduce gastrointestinal glucose production.
DEVIKA PT, UMA S
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