Results 271 to 280 of about 221,664 (312)
Some of the next articles are maybe not open access.
Artificial Organs, 1979
ABSTRACTThe plasma concentrations of methane and ethane thiols have been determined during the course of acute liver failure by a gas‐chromatographic technique, and a prognostic evaluation is possible using this analysis. Further, the effects of some therapeutic measures, notably hemoperfusion, on the thiol levels have been investigated.
C J, Holloway +3 more
openaire +2 more sources
ABSTRACTThe plasma concentrations of methane and ethane thiols have been determined during the course of acute liver failure by a gas‐chromatographic technique, and a prognostic evaluation is possible using this analysis. Further, the effects of some therapeutic measures, notably hemoperfusion, on the thiol levels have been investigated.
C J, Holloway +3 more
openaire +2 more sources
Thiols and the chemoprevention of cancer
Current Opinion in Pharmacology, 2007Thiols such as glutathione interfere with the complex carcinogenic process. Under stress conditions, they scavenge harmful molecules: Glutathione conjugation of electrophilic carcinogens may prevent tumor initiation, and reduced thiols may defend against oxidative stress. Thus, associated chemopreventive strategies involve enhancement of antioxidant or
Wolfgang W, Huber, Wolfram, Parzefall
openaire +2 more sources
Nature, 1959
WE have recently shown1,2 that β-mercaptoethanol (a strongly reducing –SH-containing substance) markedly inhibits morphogenetic movements (gastrulation, closure of neural plate) in amphibian eggs. The oxidized counterpart of β-mercaptoethanol (dithiodiglycol) produces a thickening of the neural plate; the same type of abnormalities can be obtained with
openaire +2 more sources
WE have recently shown1,2 that β-mercaptoethanol (a strongly reducing –SH-containing substance) markedly inhibits morphogenetic movements (gastrulation, closure of neural plate) in amphibian eggs. The oxidized counterpart of β-mercaptoethanol (dithiodiglycol) produces a thickening of the neural plate; the same type of abnormalities can be obtained with
openaire +2 more sources
Nature, 1957
A NEW thiol has been found in the red kidney bean, Phaseolus vulgaris, and in certain other legumes. The thiol is the principal non-protein thiol of these plants. Glutathione, when present, occurs at much lower concentrations. A provisional name, ‘phaseothione’, has been assigned to this compound, pending the determination of its chemical structure.
openaire +2 more sources
A NEW thiol has been found in the red kidney bean, Phaseolus vulgaris, and in certain other legumes. The thiol is the principal non-protein thiol of these plants. Glutathione, when present, occurs at much lower concentrations. A provisional name, ‘phaseothione’, has been assigned to this compound, pending the determination of its chemical structure.
openaire +2 more sources
Journal of Ocular Pharmacology and Therapeutics, 2000
The high content of glutathione (GSH) in the lens is believed to protect the thiols in structural proteins and enzymes for proper biological functions. The lens has both biosynthetic and regenerating systems for GSH to maintain its large pool size (4-6 mM).
openaire +2 more sources
The high content of glutathione (GSH) in the lens is believed to protect the thiols in structural proteins and enzymes for proper biological functions. The lens has both biosynthetic and regenerating systems for GSH to maintain its large pool size (4-6 mM).
openaire +2 more sources
Thiol labeling with bromobimanes
1987Publisher Summary This chapter describes the use of three bromobimanes for fluorescent labeling of biological systems. The three bromobimanes, mBBr, bBBr, and qBBr, are commercially available. Bromobimanes are derived from a basic structure (two fused five-membered rings) with the requisite minimal size.
N S, Kosower, E M, Kosower
openaire +2 more sources
Annual Review of Microbiology, 2001
▪ Abstract Glutathione metabolism is associated with oxygenic cyanobacteria and the oxygen-utilizing purple bacteria, but is absent in many other prokaryotes. This review focuses on novel thiols found in those bacteria lacking glutathione. Included are glutathione amide and its perthiol, produced by phototrophic purple sulfur bacteria and apparently ...
openaire +2 more sources
▪ Abstract Glutathione metabolism is associated with oxygenic cyanobacteria and the oxygen-utilizing purple bacteria, but is absent in many other prokaryotes. This review focuses on novel thiols found in those bacteria lacking glutathione. Included are glutathione amide and its perthiol, produced by phototrophic purple sulfur bacteria and apparently ...
openaire +2 more sources
2001
The thiol redox status of intracellular and extracellular compartments is critical in the determination of protein structure, regulation of enzyme activity, and control of transcription factor activity and binding. Thiol antioxidants act through a variety of mechanisms, including (1) as components of the general thiol/disulfide redox buffer, (2) as ...
openaire +2 more sources
The thiol redox status of intracellular and extracellular compartments is critical in the determination of protein structure, regulation of enzyme activity, and control of transcription factor activity and binding. Thiol antioxidants act through a variety of mechanisms, including (1) as components of the general thiol/disulfide redox buffer, (2) as ...
openaire +2 more sources
Spectrophotometric assay of thiols
1987Publisher Summary This chapter summarizes the chief methods in use for thiols in general. These methods exploit either of the two principal properties of the SH group—namely, its capacity for oxidation or substitution. Oxidizing agents may be of analytical value if they do not oxidize thiols further than disulfides (that is, to sulfinic or sulfonic ...
openaire +2 more sources