Results 121 to 130 of about 5,819 (161)
Proactive pharmacogenomics in azathioprine-treated pediatric inflammatory bowel disease at a Chinese tertiary hospital. [PDF]
Front PharmacolLong CY, Huang Y.
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The NUDIX hydrolase NUDT5 regulates thiopurine metabolism and cytotoxicity. [PDF]
J Clin InvestMaillard M +11 more
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Clinically actionable pharmacogenomic variants for anticancer therapy in Nigeria: first comprehensive variant profiling in underrepresented Nigerian cohorts. [PDF]
BMC Med GenomicsUkpe MP, Ezeanuka AC.
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[Pharmacogenetic study of thiopurine S-methyltransferase (TPMT) and thiopurine toxicity].
Revista espanola de enfermedades digestivas, 2003 H, Corominas +3 more
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Management of Patients with IBD and History of Cancer. [PDF]
Cancers (Basel)Faggiani I +10 more
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The Role of Cyclosporine in the Treatment of Severe Ulcerative Colitis in the Pediatric Population: A Narrative Review Exploring Known Strategies and New Possibilities. [PDF]
J Clin MedDancewicz A +4 more
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British Journal of Hospital Medicine, 2013
Thiopurines are a class of immunosuppressant and antineoplastic drugs developed by Gertrude Elion and George Hitchings and patented in 1953 for use to treat leukaemia, then used to prevent transplant rejection (Marx, 2005).
Kl, de Wit, Be, White, D, Goldsmith
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Thiopurines are a class of immunosuppressant and antineoplastic drugs developed by Gertrude Elion and George Hitchings and patented in 1953 for use to treat leukaemia, then used to prevent transplant rejection (Marx, 2005).
Kl, de Wit, Be, White, D, Goldsmith
openaire +3 more sources
Investigational New Drugs, 2005
The thiopurine drugs, 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) are commonly used cytotoxic agents. A derivative of 6-MP, azathioprine, is commonly used as an immunosuppressant. A prominent route for the metabolism of these agents is mediated by the enzyme thiopurine methyltransferase (TPMT).
Sally, Coulthard, Linda, Hogarth
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The thiopurine drugs, 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) are commonly used cytotoxic agents. A derivative of 6-MP, azathioprine, is commonly used as an immunosuppressant. A prominent route for the metabolism of these agents is mediated by the enzyme thiopurine methyltransferase (TPMT).
Sally, Coulthard, Linda, Hogarth
openaire +2 more sources