Results 21 to 30 of about 14,349 (139)

Mitochondrial thiol-disulfide system under acute hypoxia and hypoxic-hyperoxic adaptation [PDF]

The Ukrainian Biochemical Journal, 2014
The authors investigated the state of mitochondrial glutathione pool (reduced and oxidized glutathione, protein-GSH mixed disulfides), content of carbonyl groups and free sulfhydryl groups of proteins, protein expression of key mitochondrial antioxidant ...
O. A. Gonchar, I. N. Mankovska
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Oxidized Forms of Ergothioneine Are Substrates for Mammalian Thioredoxin Reductase

Antioxidants, 2022
Ergothioneine (EGT) is a sulfur-containing amino acid analog that is biosynthesized in fungi and bacteria, accumulated in plants, and ingested by humans where it is concentrated in tissues under oxidative stress.
Kaelyn A. Jenny, Gracyn Mose, Daniel J. Haupt, Robert J. Hondal   +3 more
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The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function

Antioxidants, 2018
Cysteine and methionine residues are the amino acids most sensitive to oxidation by reactive oxygen species. However, in contrast to other amino acids, certain cysteine and methionine oxidation products can be reduced within proteins by dedicated ...
Sofia Lourenço dos Santos, Isabelle Petropoulos, Bertrand Friguet   +2 more
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One cysteine is enough: A monothiol Grx can functionally replace all cytosolic Trx and dithiol Grx

Redox Biology, 2020
Glutaredoxins are small proteins of the thioredoxin superfamily that are present throughout life. Most glutaredoxins fall into two major subfamilies.
Jannik Zimmermann, Julian Oestreicher, Steffen Hess, Johannes M. Herrmann, Marcel Deponte, Bruce Morgan   +5 more
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Thiol/Disulfide system plays a crucial role in redox protection in the acidophilic iron-oxidizing bacterium Leptospirillum ferriphilum.

PLoS ONE, 2012
Thiol/disulfide systems are involved in the maintenance of the redox status of proteins and other molecules that contain thiol/disulfide groups. Leptospirillum ferriphilum DSM14647, an acidophilic bacterium that uses Fe(2+) as electron donor, and ...
Javiera Norambuena, Rodrigo Flores, Juan P Cárdenas, Raquel Quatrini, Renato Chávez, Gloria Levicán   +5 more
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Interaction of recombinant form of NADPH-dependent thioredoxin reductase from rice with thioredoxin from two plant and bacterial sources [PDF]

مجله بیوتکنولوژی کشاورزی, 2014
Maintaining redox homeostasis in the cell is critical for different cellular metabolisms and signal transduction pathways. In plants different molecular mechanisms are involved in maintaining cellular redox homeostasis.
Hadiyeh Eslam Panah, Azar Shah Piri, Ehsan Sheykholeslam   +2 more
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Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells

Cell Reports, 2022
Summary: Phenotype-based screening can identify small molecules that elicit a desired cellular response, but additional approaches are required to characterize their targets and mechanisms of action.
Fraser D. Johnson, John Ferrarone, Alvin Liu, Christina Brandstädter, Ravi Munuganti, Dylan A. Farnsworth, Daniel Lu, Jennifer Luu, Tianna Sihota, Sophie Jansen, Amy Nagelberg, Rocky Shi, Giovanni C. Forcina, Xu Zhang, Grace S.W. Cheng, Sandra E. Spencer Miko, Georgia de Rappard-Yuswack, Poul H. Sorensen, Scott J. Dixon, Udayan Guha, Katja Becker, Hakim Djaballah, Romel Somwar, Harold Varmus, Gregg B. Morin, William W. Lockwood   +25 more
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Identification of Multiple Soluble Fe(III) Reductases in Gram-Positive Thermophilic Bacterium Thermoanaerobacter indiensis BSB-33

International Journal of Genomics, 2014
Thermoanaerobacter indiensis BSB-33 has been earlier shown to reduce Fe(III) and Cr(VI) anaerobically at 60°C optimally. Further, the Gram-positive thermophilic bacterium contains Cr(VI) reduction activity in both the membrane and cytoplasm.
Subrata Pal
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Comparative molecular modeling study of Arabidopsis NADPH-dependent thioredoxin reductase and its hybrid protein. [PDF]

PLoS ONE, 2012
2-Cys peroxiredoxins (Prxs) play important roles in the protection of chloroplast proteins from oxidative damage. Arabidopsis NADPH-dependent thioredoxin reductase isotype C (AtNTRC) was identified as efficient electron donor for chloroplastic 2-Cys Prx ...
Yuno Lee, Songmi Kim, Prettina Lazar, Jeong Chan Moon, Swan Hwang, Sundarapandian Thangapandian, Youngsik Shon, Kyun Oh Lee, Sang Yeol Lee, Keun Woo Lee   +9 more
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The effect of thioredoxin and prochymosin coexpression on the refolding of recombinant alpaca chymosin

Вавиловский журнал генетики и селекции, 2023
The milk-clotting enzyme chymosin is a member of the group of aspartate proteinases. Chymosin is the main component of rennet traditionally obtained from the stomachs of dairy calves and widely used to coagulate milk in the production of various types of
S. V. Belenkaya, D. N. Shcherbakov, A. I. Chapoval, T. I. Esina, V. V. Elchaninov   +4 more
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