Results 171 to 180 of about 197,748 (297)

Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells

, 2015
Jennifer E. Hrabe, Brianne R. O’Leary, Melissa A. Fath, Samuel N. Rodman, Anna M. Button, Frederick E. Domann, Douglas R. Spitz, James J. Mezhir   +7 more
openalex   +2 more sources

Redox-Regulation of Photorespiration through Mitochondrial Thioredoxin o1 [PDF]

, 2019
Ole Reinholdt, Saskia Schwab, Youjun Zhang, Jean‐Philippe Reichheld, Alisdair R. Fernie, Martin Hagemann, Stefan Timm   +6 more
openalex   +1 more source

Hypercapnia Effects on Lung Function

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
CO2 is a signaling molecule that disrupts alveolar fluid clearance and ion transport, impairs alveolar repair, and promotes mitochondrial and endoplasmic reticulum dysfunction. It suppresses innate immunity, host defense, and inflammation, while increasing airway contractility.
Seungseo Choi, Laura A. Dada, Jacob I. Sznajder   +2 more
wiley   +1 more source

Structure-based identification of a non-covalent thioredoxin reductase inhibitor with proven ADMET suitability. [PDF]

J Enzyme Inhib Med Chem
Lamanna G, Augello G, Ronga L, Tesauro D, Silvestri I, Azzolina A, Cervello M, Mangiatordi GF, Saviano M.   +8 more
europepmc   +1 more source

Expression of peroxiredoxin and thioredoxin in human lung cancer and paired normal lung [PDF]

, 2006
Joo Hun Park, Young Sun Kim, Hye Lim Lee, Jin Young Shim, Keu Sung Lee, Yoon Jung Oh, Seung Soo Shin, Young Hwa Choi, Kwang Joo Park, Rae Woong Park, Sung Chul Hwang   +10 more
openalex   +1 more source

CRISPR‐Cas9‐Generated TXNDC15 c.560delA Homozygous Mouse Model Exhibits Meckel–Gruber Syndrome Phenotype

genesis, Volume 64, Issue 1, February 2026.
ABSTRACT To determine whether TXNDC15 variation causes Meckel–Gruber syndrome (MKS), we assessed the pathogenicity of the frameshift variant c.560delA. A CRISPR–Cas9 generated mouse model carrying the equivalent Txndc15 c.512delA mutation was analyzed at embryonic day 15.5.
Yang Liu, Hui Wang, Liyuan Chen, Xiaoxia Wu, Zhiyong Xu, Qingfa Huang, Hu Zhang, Xiushu Cao, Xinyuan Liang, Xingjian Zhong, Caiqun Luo   +10 more
wiley   +1 more source

Characterization of Pilin A and Thioredoxin A Mutant Strains of Acinetobacter baumannii, From a Transposon Insertion Library, for Pili Production and Virulence-Associated Properties. [PDF]

Microbiologyopen
Aki J, Papp SB, Polk B, Jeffreys S, Tompkins MP, Kalalah AA, Eppinger M, Zhang G, Guentzel MN, Chambers JP, Arulanandam BP, Yu JJ.   +11 more
europepmc   +1 more source

Cytosolic Thioredoxin Peroxidase I and II Are Important Defenses of Yeast against Organic Hydroperoxide Insult [PDF]

, 2004
Daniela Cristina Munhoz, Luís Eduardo Soares Netto   +1 more
openalex   +1 more source

Thioredoxin, thioredoxin-interacting protein and digestive diseases

World Chinese Journal of Digestology, 2011
Jie-Lin Yang, Dong-Qiang Zhao, Li-Ying Feng   +2 more
openaire   +1 more source

Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Muhammad Maaz, Shehnshah Zafar, Anum Shoukat, Nudrat Khursheed, Matteo Bordiga, Amna Junaid   +7 more
wiley   +1 more source