Results 161 to 170 of about 198,692 (251)

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

open access: yesPhytotherapy Research, Volume 40, Issue 10, Page 6005-6042, October 2026.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen   +4 more
wiley   +1 more source

Bacterial Contribution to Hydrogen Peroxide Decomposition in Lake Erie Cyanobacterial Harmful Algal Bloom Communities Is Dependent on Bloom Stage

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 5, October 2026.
A seasonal time series metatranscriptome dataset suggests that neutralising hydrogen peroxide in Microcystis blooms requires a complex division of labour that is further complicated by seasonality and bloom development. ABSTRACT Cyanobacterial harmful algal blooms (cHABs) are expanding globally and often involve toxin‐producing species such as ...
Chelsea E. Donovan   +9 more
wiley   +1 more source

Pathways of Epithelial Barrier Breakdown and Remodeling in Esophageal Organoids by Commonly Used Surfactants

open access: yesAllergy, Volume 81, Issue 10, Page 3659-3672, October 2026.
This study shows that SDS and CAPB directly impair esophageal epithelial barrier integrity in primary EoE‐derived models. SDS induces stronger inflammatory, oxidative stress, and keratinization responses than CAPB. Both surfactants promote epithelial remodeling and partial epithelial‐mesenchymal transition (EMT), with CAPB showing a distinct ...
Ozge Ardicli   +60 more
wiley   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

open access: yesActa Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Thioredoxin reductase-1 facilitates cellular plasticity and stemness mediated by TGF-β1 in non-small cell lung cancer. [PDF]

open access: yesCancer Biol Ther
Lang YD   +11 more
europepmc   +1 more source

ITCH‐Mediated Ubiquitination and Degradation of THBS1: A Key Mechanism for Enhancing Mitochondrial Biogenesis and Alleviating Mouse Skeletal Muscle Atrophy

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Skeletal muscle atrophy is tightly associated with maladaptive alterations in mitochondrial function and morphology. Itchy E3 ubiquitin‐protein ligase (ITCH) modulates mitochondria, and thrombospondin 1 (THBS1) positively regulates muscle atrophy, but their roles in muscle atrophy are unclear. Methods A muscle atrophy model was established
Wan Yu, Yanteng Wang, Na Li, Difei Wang
wiley   +1 more source

Transcriptomic and proteomic signatures underlying nymphal adaptation and foam production in the forage pest Mahanarva spectabilis

open access: yesInsect Molecular Biology, Volume 35, Issue 5, Page 556-575, October 2026.
RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour   +8 more
wiley   +1 more source

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