The mechanism of action of auranofin analogs in B. cenocepacia revealed by chemogenomic profiling
Drug repurposing efforts led to the discovery of bactericidal activity in auranofin, a gold-containing drug used to treat rheumatoid arthritis. Auranofin kills Gram-positive bacteria by inhibiting thioredoxin reductase, an enzyme that scavenges reactive ...
Dustin T. Maydaniuk +10 more
doaj +1 more source
Roles of Thioredoxin Reductase during the Aerobic Life of Lactococcus lactis
Karin Vido +6 more
openalex +1 more source
Effects of Overexpression of Copper-Zinc and Manganese Superoxide Dismutases, Catalase, and Thioredoxin Reductase Genes on Longevity in Drosophila melanogaster [PDF]
William C. Orr +3 more
openalex +1 more source
Selenium in Thioredoxin Reductase: A Mechanistic Perspective
Brian M. Lacey +3 more
openalex +2 more sources
Thioredoxin reductase: A novel, independent prognostic marker in patients with hepatocellular carcinoma [PDF]
Chunyan Li +3 more
openalex +1 more source
Thioredoxin Reductase and Organometallic Complexes: A Pivotal System to Tackle Multidrug Resistant Tumors? [PDF]
Salmain M +6 more
europepmc +1 more source
Thioredoxin Reductase Activity Predicts Gold Nanoparticle Radiosensitization Effect [PDF]
Sébastien Penninckx +3 more
openalex +1 more source
Thioredoxin Reductase-1 Negatively Regulates HIV-1 Transactivating Protein Tat-dependent Transcription in Human Macrophages [PDF]
Parisa Kalantari +7 more
openalex +1 more source

