Results 81 to 90 of about 46,151 (247)

The Human Thioredoxin System: Modifications and Clinical Applications [PDF]

Iranian Journal of Basic Medical Sciences, 2011
The thioredoxin system, comprising thioredoxin (Trx), thioredoxin reductase (TrxR) and NADPH, is one of the major cellular antioxidant systems, implicated in a large and growing number of biological functions.
Seyed Isaac Hashemy
doaj  

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Modeling Thioredoxin Reductase‐Like Activity with Cyclic Selenenyl Sulfides: Participation of an NH⋅⋅⋅Se Hydrogen Bond through Stabilization of the Mixed Se−S Intermediate [PDF]

, 2019
Kenta Arai, Takahiko Matsunaga, Haruhito Ueno, Nozomi Akahoshi, Yuumi Sato, Gaurango Chakrabarty, Govindasamy Mugesh, Michio Iwaoka   +7 more
openalex   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source

The Levels of Ribonucleotide Reductase, Thioredoxin, Glutaredoxin 1, and GSH Are Balanced in Escherichia coli K12 [PDF]

, 1996
Antonio Miranda–Vizuete, Antonio Rodríguez‐Ariza, Fermı́n Toribio, Arne Holmgren, Juan López‐Barea, Carmen Pueyo   +5 more
openalex   +1 more source

The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity [PDF]

, 2023
Junran Zhang, Chandra Bhushan Prasad, Adrian Oo, Zhaojun Qiu, Na Li, Deepika Singh, Xiwen Xin, Young‐Jae Cho, Zaibo Li, Xiaoli Zhang, Chunhong Yan, Qingfei Zheng, Jimin Shao, Qi‐En Wang, Baek Kim   +14 more
openalex   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, Volume 158, Issue 7, Page 1927-1940, 1 April 2026.
What's new? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function

Antioxidants, 2018
Cysteine and methionine residues are the amino acids most sensitive to oxidation by reactive oxygen species. However, in contrast to other amino acids, certain cysteine and methionine oxidation products can be reduced within proteins by dedicated ...
Sofia Lourenço dos Santos, Isabelle Petropoulos, Bertrand Friguet   +2 more
doaj   +1 more source

Selenium biofortification: integrating one health and sustainability

Journal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 1955-1967, 15 March 2026.
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín   +3 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet, Belén Pepió‐Tárrega, Javier Saiz‐Poseu, Alba López‐Moral, Faiz Ullah, Victor J. Yuste, Daniel Ruiz‐Molina, Salvio Suárez‐García   +7 more
wiley   +2 more sources