Results 71 to 80 of about 45,317 (203)

Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of overtraining in trained endurance athletes reduced exercise performance without impairing glucose tolerance. In skeletal muscle, overtraining was associated with increased expression of lipid metabolism‐related proteins, enhanced mitochondrial biogenesis and preserved insulin signalling, despite elevated oxidative ...
Geneviève J. DesOrmeaux, Henver S. Brunetta, Pierre‐Andre Barbeau, Alexandra M. Coates, Christopher Pignanelli, Fasih A. Rahman, Jamie F. Burr, Graham P. Holloway   +7 more
wiley   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source

The Role of Thioredoxin Reductases in Brain Development

PLoS ONE, 2008
The thioredoxin-dependent system is an essential regulator of cellular redox balance. Since oxidative stress has been linked with neurodegenerative disease, we studied the roles of thioredoxin reductases in brain using mice with nervous system (NS)-specific deletion of cytosolic (Txnrd1) and mitochondrial (Txnrd2) thioredoxin reductase.
Soerensen, Jonna, Jakupoglu, Cemile, Beck, Heike, Förster, Heidi, Schmidt, Jörg, Schmahl, Wolfgang W., Schweizer, Ulrich, Conrad, Marcus, Brielmeier, Markus   +8 more
openaire   +5 more sources

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

Differential expression of disulfide reductase enzymes in a free-living platyhelminth (Dugesia dorotocephala).

PLoS ONE, 2017
A search of the disulfide reductase activities expressed in the adult stage of the free-living platyhelminth Dugesia dorotocephala was carried out. Using GSSG or DTNB as substrates, it was possible to obtain a purified fraction containing both GSSG and ...
Alberto Guevara-Flores, Álvaro Miguel Herrera-Juárez, José de Jesús Martínez-González, Irene Patricia Del Arenal Mena, Óscar Flores-Herrera, Juan Luis Rendón   +5 more
doaj   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo

Acta Pharmaceutica, 2015
Green tea is a favorite beverage and its extracts are popular components of dietary supplements. The aim of the present in vivo study was to obtain detailed information about the effect of a standard green tea extract (Polyphenon, P), at different doses,
Bártíková Hana, Skálová Lenka, Valentová Kateřina, Matoušková Petra, Szotáková Barbora, Martin Jan, Kvita Vojtěch, Boušová Iva   +7 more
doaj   +1 more source

Nitrogen‐Starved Wheat: A Multi‐Omics Perspective From Epigenome Regulation to Grain Quality

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 3, September 2026.
This review establishes epigenetic regulation, specifically H3K27ac and H3K27me3 dynamics at nitrogen transporter, assimilation, and storage protein loci, as a principal determinant of cultivar‐specific nitrogen use efficiency in hexaploid wheat, independent of DNA sequence variation, and identifies the rhizosphere microbiome as an integral but ...
Baber Ali, Zeeshan Khan, Nijat Imin
wiley   +1 more source

Edible Insect Allergens: An Emerging Food Safety Challenge

Sustainable Food Proteins, Volume 4, Issue 3, September 2026.
Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu, Cassandra Maya, John J. Love, Huilian Che, Ke Chen, Jing Zhao   +5 more
wiley   +1 more source

Transcriptional Regulation of HSP60, HSP70, and HSP90 in Response to Selenium Nanoparticles and Sodium Selenite in Periparturient Cloned Saanen Goats and Their Offspring

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Selenium nanoparticles (SeNPs) outperform sodium selenite in raising serum selenium levels and suppressing HSP60, HSP70, and HSP90 transcription in periparturient goats and their offspring, indicating reduced cellular stress regardless of cloning status.
Gholam‐Ali Kojouri, Hossein Hassanpour, Ahmad Yousefi   +2 more
wiley   +1 more source