Results 71 to 80 of about 162,334 (201)

Biochemical Characterization of the Thioredoxin Reductase from Babesia bovis

, 2014
This paper addresses the identification, cloning, expression, purification and functional characterization of thioredoxin reductase from Babesia bovis, the etiological agent of babesiosis.
Guerrero, Sergio Adrian, Thompson, Carolina S., Arias, Diego Gustavo, Iglesias, Alberto Alvaro, Thompson, Carolina Soledad, Regner, Erika Lucía   +5 more
core   +1 more source

Biological Effects of Selenium‐Containing Ionic Liquids: Cytotoxicity, Mercury Interaction, and Antiproliferative Activity in Glioblastoma Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Guilherme Schmitt Rieder, Alessandro de Souza Prestes, Fernanda D'Avila da Silva, Nilda de Vargas Barbosa, Alix Y. Bastidas Ángel, Mariana F. Soares, Carolina Martins Fernandes, Maria Anttônia Oliveira Petersen, Manuela Moura Silva, Juliete Nathali Scholl, Fabrício Figueiró, Pablo Andrei Nogara, Laura Orian, Eduardo E. Alberto, Michael Aschner, Diogo Onofre Gomes de Souza, Debora Guerini de Souza, João Batista Teixeira da Rocha   +17 more
wiley   +1 more source

Inhibition of thioredoxin reductase by lanthanum chloride

, 2012
Lanthanum chloride (LaCl3) is a good inhibitor of both the cytosolic and mitochondrial thioredoxin reductase with IC50 values of 1.75 and 7.46 μM, respectively.
CITTA, ANNA, CESARO, LUCA, RIGOBELLO, MARIA PIA, SCUTARI, GUIDO, BINDOLI, ALBERTO, FOLDA, ALESSANDRA   +5 more
core   +1 more source

Time‐Resolved Effects of Cold Atmospheric Plasma on E. coli GW‐AmxH19 Transcriptome and Proteome in an Emulated Wastewater Environment

PROTEOMICS, EarlyView.
ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt, Dominik Schneider, Julia Rielicke, Susanne Sievers, Veronika Hahn, Mechthild Bömeke, Anja Poehlein, Dirk Albrecht, Juergen F. Kolb, Katharina Riedel, Rolf Daniel, Daniela Zühlke   +11 more
wiley   +1 more source

NK-lysin, a Disulfide-containing Effector Peptide of T-lymphocytes, Is Reduced and Inactivated by Human Thioredoxin Reductase

, 1996
The cytotoxic and antibacterial polypeptide NK-lysin has a molecular mass of approximately 9 kDa and contains three disulfide bonds. The activity was highly dependent on intact disulfides, because the bactericidal effect on Escherichia coli and the ...
Holmgren, A,, Arne Holmgren, Andersson, M,, Spyrou, G, Holmgren, A.,, Spyrou, Giannis,, Giannis Spyrou, Mats Andersson, Andersson, M.,   +8 more
core   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

Pest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano, Carmen Scieuzo, Rosanna Salvia, Riccardo Moretti, Flora Cozzolino, Maria Monti, Heiko Vogel, Patrizia Falabella   +7 more
wiley   +1 more source

Activity of rat cytosolic thioredoxin reductase is strongly decreased by trans-[bis(2-amino-5methylthiazole)tetrachlororuthenate(III)]: First report of relevant thioredoxin reductase inhibition for a ruthenium compound

, 2007
A novel '' Keppler type '' ruthenium(III) compound trans[bis(2-amino 5-methylthiazole)tetrachlororuthenate(III)] 1, of potential interest as an anticancer agent, was designed, synthesized, and characterized.
P. MURA, Sorrentino F., P. ZANELLO, Corsini M., Rigobello M. P., A. CASINI, Mura, Pasquale, RIGOBELLO, MARIA PIA, ZANELLO P, SORRENTINO F, CORSINI M, Zanello, Piero, CAMALLI M, MESSORI L., Sorrentino, Francesca, BINDOLI, ALBERTO, Camalli M., M. CORSINI, Camalli, Mercedes, F. SORRENTINO, GABBIANI C, Bindoli A., L. MESSORI, Gabbiani C., M. CAMALLI, GABBIANI, CHIARA, Zanello P., Casini A., Messori, Luigi, A. BINDOLI, Casini, Angela, Corsini, Maddalena, M. P. RIGOBELLO, MURA P, Mura P., CASINI A, Rigobello MP, Messori L, Bindoli A   +38 more
core   +1 more source

Evolutionary Mechanisms of Coagulation Factors in Cetaceans During Aquatic Adaptation

Integrative Zoology, EarlyView.
Compared with Bos taurus, T. truncatus showed shorter prothrombin time and thrombin time but prolonged activated partial thromboplastin time, indicating pathway‐specific remodeling of coagulation. Evolutionary analyses identified 18 positively selected genes and accelerated F11 evolution, while functional assays revealed increased coagulation factor ...
Wenjun Lv, Wanfei Deng, Fei Deng, Shixia Xu, Wenhua Ren   +4 more
wiley   +1 more source

Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo

Acta Pharmaceutica, 2015
Green tea is a favorite beverage and its extracts are popular components of dietary supplements. The aim of the present in vivo study was to obtain detailed information about the effect of a standard green tea extract (Polyphenon, P), at different doses,
Bártíková Hana, Skálová Lenka, Valentová Kateřina, Matoušková Petra, Szotáková Barbora, Martin Jan, Kvita Vojtěch, Boušová Iva   +7 more
doaj   +1 more source

Differential expression of disulfide reductase enzymes in a free-living platyhelminth (Dugesia dorotocephala).

PLoS ONE, 2017
A search of the disulfide reductase activities expressed in the adult stage of the free-living platyhelminth Dugesia dorotocephala was carried out. Using GSSG or DTNB as substrates, it was possible to obtain a purified fraction containing both GSSG and ...
Alberto Guevara-Flores, Álvaro Miguel Herrera-Juárez, José de Jesús Martínez-González, Irene Patricia Del Arenal Mena, Óscar Flores-Herrera, Juan Luis Rendón   +5 more
doaj   +1 more source