Results 101 to 110 of about 8,827 (223)
Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides [PDF]
, 2014 A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure reaction of phenyl-1-(thiophen-2-yl) prop-2-en-1-ones with thiosemicarbazide in alcoholic basic medium.
Anbazhagan, S. +2 more
core
Nitrofurazone and its nitroheterocyclic analogues: a study of the electrochemical behavior in aqueous medium [PDF]
, 2013 The biological action of drugs with potential antichagasic activities can be better understood by knowing their reduction mechanism. For this proposal, the electrochemical reduction of nitrofurazone (NF) and its analogues, nitrofurfurilidene ...
Brito, Charles de Lima +3 more
core +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2019 In the title compound, C16H14N3OSCl, a Schiff base derivative of a thiosemicarbazide with a flavanone, the 4-chlorophenyl ring is inclined to the benzene ring of the chromane ring system by 30.72 (12)°.
Ruokuosenuo Zatsu +4 more
doaj +1 more source
The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
Molecules, 2011 New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5 ...
Abu Bakar Mohamad +3 more
doaj +1 more source
Thiosemicarbazide: A New Toxic Derivative of Thiourea.
Experimental Biology and Medicine, 1949 SummaryThiorsemicarbazide, a derivative of both thiourea and hydrazine, has proved to differ from other toxic thioureas previously studied. Instead of producing fatal pulmonary edema in a limited number of animal species and not harming others at equivalent dose levels, thiosemicarbazide caused convulsions and death within 1 to 3 hours in the 6 species
openaire +2 more sources
4-Cyclohexyl-1-(2-methoxybenzoyl)thiosemicarbazide with an unknown solvent
IUCrData, 2018 In the title compound, C15H21N3O2S, a short intramolecular N—H...O hydrogen bond generates an S(6) ring. The molecule is twisted with a dihedral angle between the benzene ring and the mean plane of the cyclohexyl ring being 58.90 (6)°.
Rahul Chaurasia +4 more
doaj +1 more source
Role of the Bifunctional Aminoacyl-tRNA Synthetase EPRS in Human Disease [PDF]
, 2020 Aminoacyl-tRNA synthetases (AARS) are a class of enzymes that catalyze the charging of tRNAs with cognate amino acids, a critical step that contributes to the fidelity of protein synthesis.
Kudlapur, Nathan
core
Royal Society Open ScienceInflammation is a complex physiological response associated with the onset and progression of various disorders, including diabetes. In this study, we synthesized a series of diclofenac acid derivatives and evaluated their potential anti-diabetic and ...
Asma Sardar +8 more
doaj +1 more source
, 2013 This paper presents a novel liver model that mimics the liver sinusoid where most liver activities occur. A key aspect of our current liver model is a layered co-culture of primary rat hepatocytes (PRHs) and primary rat liver sinusoidal endothelial cells
Bouchard, Michael +4 more
core +1 more source
Synthesis, antibacterial and antiproliferative potential of some new 1-pyridinecarbonyl-4-substituted thiosemicarbazide derivatives [PDF]
, 2016 core +1 more source