Results 81 to 90 of about 8,827 (223)

Synthesis and evaluation of fluorimetric and colorimetric chemosensors for anions based on (oligo)thienyl-thiosemicarbazones [PDF]

open access: yes, 2012
A family of heterocyclic thiosemicarbazone dyes (3a-d) containing thienyl groups has been synthesized, characterized and their chromo-fluorogenic response in acetonitrile in the presence of selected anions studied.
Agostini   +89 more
core   +2 more sources

Polysaccharide‐Coated ETCA Nanoparticles Containing the Methoxyl Substituted Indole‐Thiazole Derivative and Their Antiproliferative Activity in Breast Cancer Cells

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 4, January 20, 2026.
ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares   +4 more
wiley   +1 more source

New resource-efficient and green synthesis methods for biologically active derivatives of urea [PDF]

open access: yes, 2017
Developed were highly effective solvent-free processes for preparation of substituted ureas containingpharmacophore substituents (benzhydryl ureas, dihydroquinazolinones, semicarbazones, thiosemicarbazonesand guanylhydrazones), consistent with green ...
Filimonov, Viktor Dmitrievich   +3 more
core   +2 more sources

Evaluation of a New Methylimidazole‐Containing Thiosemicarbazone as a Cu+/Cu2+‐Targeting Ligand in the Context of Alzheimer's Disease

open access: yesChemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
HXE modulates Cu(Aβ) interaction, reducing ROS production and shifting peptide aggregation in the presence of Cu from toxic amorphous aggregates to less harmful fibrillar structures. These findings highlight HXE potential to interfere with Cu‐induced oxidative stress and aggregation pathways relevant to AD.
Barbara Marinho Barbosa   +9 more
wiley   +1 more source

Butylated Hydroxytoluene Analogs: Synthesis and Evaluation of Their <em>Multipotent </em>Antioxidant Activities

open access: yesMolecules, 2012
A computer-aided predictions of antioxidant activities were performed with the Prediction Activity Spectra of Substances (PASS) program. Antioxidant activity of compounds <strong>1</strong>, <strong>3</strong>, <strong>4</
Wageeh A. Yehye   +5 more
doaj   +1 more source

Chemoproteomic identification of molecular targets of antifungal prototypes, thiosemicarbazide and a camphene derivative of thiosemicarbazide, in Paracoccidioides brasiliensis

open access: yesPLOS ONE, 2018
Paracoccidioidomycosis (PCM) is a neglected human systemic disease caused by species of the genus Paracoccidioides. The disease attacks the host's lungs and may disseminate to many other organs. Treatment involves amphotericin B, sulfadiazine, trimethoprim-sulfamethoxazole, itraconazole, ketoconazole, or fluconazole.
Joyce Villa Verde Bastos Borba   +6 more
openaire   +3 more sources

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour   +14 more
wiley   +1 more source

Synthesis, In Vitro Screening and Docking Studies of New Thiosemicarbazide Derivatives as Antitubercular Agents

open access: yesMolecules, 2019
A series of thiosemicarbazide derivatives was designed and synthesized by reaction of carboxylic acid hydrazide with isothiocyanates. The molecular structures of the investigated thiosemicarbazides were confirmed and characterized by spectroscopic ...
Monika Pitucha   +7 more
doaj   +1 more source

Sinteza i antimikrobno djelovanje novih derivata tienopirimidina [PDF]

open access: yes, 2006
Reaction of heteroaromatic o-aminonitrile with ethyl N-/bis(methylthio)methyleneamino acetate resulted in annelation of a thieno/3,2-e/imidazo/1,2-c/pyrimidine moiety in a one step process.
ABDUR RAHIM   +5 more
core   +1 more source

Targetability of hyaluronic acid nanogel to cancer cells: In vitro and in vivo studies [PDF]

open access: yes, 2017
We have, in previous work developed, characterized and evaluated the biocompatibility of an engineered hyaluronic acid nanogel. Here we assess the targetability of a hyaluronic acid nanogel towards CD44 overexpressing cells, in vitro and in vivo. Results
Correia, A.   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy