Results 71 to 80 of about 8,827 (223)
Archiv der Pharmazie, Volume 359, Issue 3, March 2026.In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi +17 more
wiley +1 more source
Molecules, 1999 The title 3-amino-2-thiohydantoins 3 has been prepared in very good yields by the reaction of alkyl isothiocynatocarboxylates 1 with hydrazine hydrate.The synthesis of starting isothiocyanates as well as spectral data of 3-aminothiohydantoins and alkyl ...
Martin Kovac +2 more
doaj +1 more source
Synthesis and anti-Aphid Aphis gossypii (Glover) activity of some new quinoline derivatives [PDF]
, 2010 A series of quinoline derivatives have been elaborated fromreaction of 2-(m- and p-acetylanilino)-quinolines 6a-b withaldehydes under Claisen-Schmidt conditions followed by cyclization with phenyl hydrazine and hydroxylamine.
El Kafafy, Abdel Kader +3 more
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Synthesis of a DNA-targeting nickel (II) complex with testosterone thiosemicarbazone which exhibits selective cytotoxicity towards human prostate cancer cells (LNCaP) [PDF]
, 2015 Testosterone thiosemicarbazone, L and its nickel (II) complex 1 were synthesized and characterized by using FTIR, CHN, (1)H NMR, and X-ray crystallography.
Cheah, Yoke Kqueen +6 more
core +1 more source
Biotechnology and Applied Biochemistry, Volume 73, Issue 1, Page 14-27, February 2026.ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen +4 more
wiley +1 more source
Cytotoxic effect and molecular docking of 4-ethoxycarbonylmethyl-1-(piperidin-4-ylcarbonyl)-thiosemicarbazide—a novel topoisomerase II inhibitor [PDF]
, 2012 The preliminary cytotoxic effect of 4-ethoxycarbonylmethyl-1-(piperidin-4-ylcarbonyl)-thiosemicarbazide hydrochloride (1)—a potent topoisomerase II inhibitor—was measured using a MTT assay.
Agata Siwek +5 more
core +1 more source
Reprogramming Immunogenicity of Iron Oxide Nanoparticles through Sulfated Glycan Presentation
Small, Volume 22, Issue 11, 20 February 2026.This study presents a comparative analysis of heparin (HP)‐ and dextran sulfate (DS)‐coated superparamagnetic iron oxide nanoparticles (SPIONs) as a tunable immunomodulatory platform where surface chemistry dictates therapeutic function. DS‐SPIONs are preferentially internalized by myeloid cells, reprogramming them into a pro‐healing M2 phenotype ...
Negin Pournoori +8 more
wiley +1 more source
Biocompatibility of a self-assembled crosslinkable hyaluronic acid nanogel [PDF]
, 2016 Hyaluronic acid nanogel (HyA-AT) is a redox sensitive crosslinkable nanogel, obtained through the conjugation of a thiolated hydrophobic molecule to the hyaluronic acid chain.
Correia, Alexandra +5 more
core +1 more source
Coumarin‐Augmented Thiazole Hybrids as Dual Anticancer and Antibacterial Agents
Chemical Biology &Drug Design, Volume 107, Issue 2, February 2026.Compound 13, a coumarin‐thiazole hybrid, is shown engaging the ATP‐binding site of S. aureus GyrB through a novel hydrogen bond with residue SER129. The molecule exhibits dual antibacterial and anticancer activity, supporting its potential as a dual‐target topoisomerase inhibitor.
Islam K. Matar +6 more
wiley +1 more source
International Journal of Electrochemical Science, 2012 Novel corrosion inhibitor as a green chemical product namely derivative, 2-amino 5-oleyl-1,3,4-thiadiazol (AOT) was synthesized by cyclization of oleic acid. The new corrosion inhibitor was characterized by FT-IR and NMR spectroscopical methods.
Sutiana Junaedi +4 more
doaj +1 more source