Results 51 to 60 of about 6,253 (217)

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Synthesis, characterization, antimicrobial, and pharmacological evaluation of some 2, 5-disubstituted sulfonyl amino 1,3,4-oxadiazole and 2-amino-disubstituted 1,3,4-thiadiazole derivatives

Journal of Advanced Pharmaceutical Technology & Research, 2014
The presence of heterocyclic structures in diverse types of compounds, this is strongly indicative of the profound effect like structure exerts on physiologic activity, and recognition of this is abundantly reflected in efforts to find useful synthetic ...
Dilipkumar Pal, Rohit Tripathi, Desh Deepak Pandey, Preety Mishra   +3 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

4α,14α,Dimethyl-5α-cholest-8-en-3-one thiosemicarbazone

Molbank, 2006
n ...
Noureddine Mazoir, My Youssef Ait Itto, Matías Reina Artiles, Ahmed Benharref   +3 more
doaj   +1 more source

Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches

Analysis &Sensing, Volume 6, Issue 6, November 2026.
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi, Jacob T. Theismann, Michael A. Johnson   +2 more
wiley   +1 more source

Synthesis of Novel Triazinoindole-Based Thiourea Hybrid: A Study on α-Glucosidase Inhibitors and Their Molecular Docking

Molecules, 2019
A new class of triazinoindole-bearing thiosemicarbazides (1−25) was synthesized and evaluated for α-glucosidase inhibitory potential. All synthesized analogs exhibited excellent inhibitory potential, with IC50 values ranging from 1.30 ± 0.
Muhammad Taha, Foziah J. Alshamrani, Fazal Rahim, Shawkat Hayat, Hayat Ullah, Khalid Zaman, Syahrul Imran, Khalid Mohammed Khan, Farzana Naz   +8 more
doaj   +1 more source

Preparation, Spectroscopic Elucidation, Antioxidant Potential, Enzyme Inhibition, and Molecular Docking Studies of Novel Schiff Base‐Derived Thiosemicarbazones

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
The synthesis of new thiosemicarbazones bearing Schiff base was performed. The structures of the compounds were characterized through several spectroscopic methods. The antioxidant potential of these compounds was evaluated through DPPH• in vitro assays. In addition, their inhibitory activities against urease and xanthine oxidase (XO) were investigated.
Hasan Yakan, Halit Muglu, Semiha Yenigun, Tevfik Ozen   +3 more
wiley   +1 more source

1-(2,3,4-Trihydroxybenzylidene)thiosemicarbazide [PDF]

, 2010
In the title molecule, C8H9N3O3S, the thiosemicarbazide =N—NH—C(=S)—NH— fragment is twist a different degree of twist in the three independent molecules [dihedral angles = 7.6 (1), 11.6 (1) and ...
Hana Bashir Shawish, Seik Weng Ng, Shawish, H.B., Ng, S.W., M. Jamil Maah, Maah, Mohd Jamil   +5 more
core   +1 more source

Synthesis, Cytotoxic Activity, mRNA Expression, Total Oxidant and Antioxidant Status, and Molecular Modeling Studies of Novel Schiff Base–Thiosemicarbazone Hybrids

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
In this study, new Schiff base‐derived compounds were synthesized, and their structures were confirmed by FT‐IR, 1H‐NMR, 13C‐NMR, and HRMS analyses. The cytotoxic effects of the compounds on a prostate cancer cell line (PC3) were investigated, and it was determined that the compounds NZ10, NZ9, NZ7, and NZ4, in particular, exhibited potent anticancer ...
Anber M Anber, Mehmet Özbay, İlhan Özer İlhan, Hüseyin Kekeçmuhammed, Rıfat Emin Bora, Emin Saripinar, Yalçın Erzurumlu, Muhammed Tilahun Muhammed, Sadeq K. Alhag, Lamya Ahmed Alkeridis, Senem Akkoc   +10 more
wiley   +1 more source

Reaction of N-alkylisatins with 4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiosemicarbazide [PDF]

, 2013
Some N-alkylisatins were converted to corresponding thiosemicarbazones by reaction with 4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiosemicarbazide using microwave-assisted heating method.
Nguyen Dinh Thanh, Nguyen Thi Kim Giang, Dinh Thanh, N.D., Giang, N.T.K.   +3 more
core   +1 more source