Results 41 to 50 of about 5,263 (174)
Molecules, 2020 We synthesized 10 analogs of benzimidazole-based thiosemicarbazide 1 (a–j) and 13 benzimidazole-based Schiff bases 2 (a–m), and characterized by various spectroscopic techniques and evaluated in vitro for acetylcholinesterase (AchE) and ...
Bushra Adalat +8 more
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Pharmacophore Mapping Approach for Drug Target Identification: A Chemical Synthesis and in Silico Study on Novel Thiadiazole Compounds [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Compounds containing thiadiazole moiety are cognized to possess with variety of clinical and therapeutic activity. Finding a suitable drug target for newly synthesized compounds remain a major bottle neck in current high throughout ...
Rohan J. Meshram +4 more
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1,1,4-Derivatives of Thiosemicarbazide—New Non-Staining Antiozonants
, 1973 In the nature of non-staining antiozonants, a new class of compounds, 1,1,4-derivatives of thiosemicarbazide, are proposed. The mechanism of reaction of thiosemicarbazide derivatives with ozone is analogous to the mechanism of this reaction with thiourea
L. K. Zolotarevskaya +3 more
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International Journal of Electrochemical Science, 2012 Novel corrosion inhibitor as a green chemical product namely derivative, 2-amino 5-oleyl-1,3,4-thiadiazol (AOT) was synthesized by cyclization of oleic acid. The new corrosion inhibitor was characterized by FT-IR and NMR spectroscopical methods.
Sutiana Junaedi +4 more
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Molecules, 2022 The emergence of drug-resistant bacterial strains continues to be one of the major challenges of medicine. For this reason, the importance of searching for novel structures of antibacterial drugs chemically different from the currently known antibiotics ...
Sara Janowska +3 more
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Advanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.In this work, we successfully synthesized a library of novel N‐amidinyl‐benzodiazaborines, showing how these heteroaryl guanyl hydrazones are able to stabilize the retromer, a protein complex involved in the disposal of misfolded and aggregated proteins, whose malfunction is observed in multiple neurodegenerative diseases.
Alessandro Dimasi +10 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Sandeep Bindra +11 more
wiley +1 more source
Effects of Thiosemicarbazide on Audiogenic Seizures
, 1966 35 male albino rats were tested for audiogenic seizures and then divided into 5 time-delay groups. These time delays preceded bell-can stimulations following the administration of thiosemicarbazide. It was found that 1-hr. and 5-hr.
Emery E. Benson, Herman C. Salzberg
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A novel intermediate in the interaction of thiosemicarbazide with sheep liver serine hydroxymethyltransferase [PDF]
, 1992 An unusual intermediate bound to the enzyme was detected in the interaction of thiosemicarbazide with sheep liver serine hydroxymethyltransferase. This intermediate had absorbance maxima at 464 and 440 nm.
Rao, NA, Acharya, JK
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Journal of Advanced Pharmaceutical Technology & Research, 2014 The presence of heterocyclic structures in diverse types of compounds, this is strongly indicative of the profound effect like structure exerts on physiologic activity, and recognition of this is abundantly reflected in efforts to find useful synthetic ...
Dilipkumar Pal +3 more
doaj +1 more source