Results 61 to 70 of about 6,253 (217)

3-(4-Bromophenyl)-1-carbamothioyl-5-(2-carbamothioylhydrazinyl)-4,5-dihydro-1H-pyrazole-5-carboxylic Acid

Molbank
The reaction of 4-(4-bromophenyl)-2,4-dioxobutanoic acid with thiosemicarbazide, in a ratio of 1:2, when boiled in ethanol gives 3-(4-bromophenyl)-1-carbamothioyl-5-(2-carbamothioylhydrazinyl)-4,5-dihydro-1H-pyrazole-5-carboxylic acid with a good yield ...
Anastasia A. Andreeva, Maksim V. Dmitriev, Andrey N. Maslivets   +2 more
doaj   +1 more source

1,2-Dibenzoylthiosemicarbazide

Molbank
When 1-benzoylthiosemicarbazide (2) or thiosemicarbazide (1) were treated with benzoyl chloride in a basic medium, a mixture of two compounds was obtained: 1,2-dibenzoylthiosemicarbazide (3) and 1,4-dibenzoylthiosemicarbazide (4).
Burcă Ion, Badea Valentin, Todea Anamaria, Bercean Vasile-Nicolae   +3 more
doaj   +1 more source

Synthesis, Molecular Docking and Anticancer Activity of Diflunisal Derivatives as Cyclooxygenase Enzyme Inhibitors

Molecules, 2018
Cyclooxygenase enzymes play a vital role in inflammatory pathways in the human body. Apart from their relation with inflammation, the additional involvement of COX-2 enzyme with cancer activity was recently discovered.
Göknil Pelin Coşkun, Teodora Djikic, Taha Bartu Hayal, Nezaket Türkel, Kemal Yelekçi, Fikrettin Şahin, Ş. Güniz Küçükgüzel   +6 more
doaj   +1 more source

Diethylene Glycol‐Linked Ring‐Fused Bis‐Azoles: Target‐Oriented Synthesis, In Silico Screening, and Antitumor Activity

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
A series of diethylene glycol‐linked cyclic derivatives with diversity in the heterocyclic motif have been synthesized and screened for antitumor activity. Two bis‐thiazolo[3,2‐a]pyrimidinone derivatives displayed moderate cytotoxicity, high selectivity against hepatocellular carcinoma cells, promising VEGFR2, and remarkable FGFR2 inhibitory activities
Sami A. Al‐Hussain, Abdulrahman S. Alharbi, Zeinab A. Muhammad, Alyaa S. Abdel Halim, Magdi E. A. Zaki, Mark C. Bagley, Refaie M. Kassab   +6 more
wiley   +1 more source

Imidazole-Thiosemicarbazide Derivatives as Potent Anti-Mycobacterium tuberculosis Compounds with Antibiofilm Activity

Cells, 2021
Mycobacterium tuberculosis (Mtb) is an intracellular pathogenic bacterium and the causative agent of tuberculosis. This disease is one of the most ancient and deadliest bacterial infections, as it poses major health, social and economic challenges at a ...
Adrian Bekier, Malwina Kawka, Jakub Lach, Jarosław Dziadek, Agata Paneth, Justyna Gatkowska, Katarzyna Dzitko, Bożena Dziadek   +7 more
doaj   +1 more source

Synthesis, Characterization and Corrosion Inhibition on 4‐Ethyl−3‐Thiosemicarbazide Meldrum's Acid in HCl: Weight Loss, Surface Analysis, Electrochemical and DFT–Fukui Studies

Applied Research, Volume 5, Issue 5, October 2026.
The 4‐Ethyl−3‐thiosemicarbazide Meldrum's acid (4E3TSCMA) is an effective corrosion inhibitor which forms a protective film on the mild steel surface by adsorption. Experimental analyses (Electrochemical analysis, SEM‐EDX, AFM, and XPS) combined with DFT calculations (MEP, Mulliken charges, and Fukui indices), explain its molecular‐level inhibition ...
Nursyahirah Ismail, Sheikh Ahmad Izaddin Sheikh Mohd Ghazali, Noor Hidayah Pungot, Fazira Ilyana Abdul Razak, Suhaila Sapari, Nur Nadia Dzulkifli   +5 more
wiley   +1 more source

Synthetic Strategy to Novel Highly Functionalized Furan Analogues Bearing Imidazole–Thiazole Hybrids: Structural Characterization, Nanoparticle Formulations, Antimicrobial Evaluation, Molecular Docking Studies, and Molecular Dynamic Simulations

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
A novel highly functionalized furan analogues bearing imidazole–thiazole hybrids were prepared via efficient synthetic routes. Selected compounds were formulated into nanoparticle systems. Antimicrobial evaluation for all synthesized compounds and nanoformulations was evaluated against a panel of bacterial strains.
Ashraf A. Sediek, Azza A. kamel, Ola M. El‑Borady, Ahmed F. El‐Sayed, Ahmed A. El‐Rashedy, Eman Sabry   +5 more
wiley   +1 more source

Electrochemical synthesis of some thiosemicarbazide derivatives doped polypyrrole electrodes and supercapacitor applications

, 2023
Thiosemicarbazide derivatives (TSC, N-Phenyl TSC, N-Cyclohexyl TSC) doped polypyrrole (PPy) based electrodes were synthesized in one step electropolymerization method.
Eglence-Bakır, Songül, Songül Eglence-Bakır, Melih Besir Arvas, Sahin, Musa, Sibel Yazar, Yazar Aydoğan, Sibel, Arvas, Melih Besir, Musa Sahin   +7 more
core   +1 more source

Green Acid Mediated Synthesis of Imidazo[1,2‐a]Pyrimidine–Thiazole/1,3,4‐Thiadiazole Hybrids: Design, Characterization and In‐Vitro Biological Evaluation

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
A new set of imidazo[1,2‐a]pyrimidine‐thiazole/thiadiazole hybrids were developed through the molecular hybridization concept. The thiazole and thiadiazole derivatives were synthesized using water as a solvent, and the final compounds were synthesized using citric acid as an eco‐friendly catalyst.
Dinesha P, Shivakumar Naik, Udayakumar D, Maithilee S. Dhekale, Sampat Parayya Vibhutimath, Rajkumar Reddy Rajula, Revanasiddappa B.C, Nanditha Bhat, Naveena S. Veeranagaiah   +8 more
wiley   +1 more source

Kinetics and Mechanism of the Interaction of Thiosemicarbazide with Di-µ-hydroxobis(1,10-phenanthroline)di-paladium(II) ions in Aqueous Solution

, 2011
The kinetics and mechanism of the interaction between thiosemicarbazide with di-μ-hydroxobis(1,10- phenanthroline)dipalladium(II) ion complex has been followed spectrophotometrically in pseudo first order conditions in aqueous solution as a function ...
Moi, Sankar Chandra, Linert, Wolfgang, Panja, Sujit. S., Ghosh, Goutam K.   +3 more
core   +1 more source