Results 21 to 30 of about 15,360 (269)

Platinum(II), palladium(II) and gold(III) complexes containing 1,1,4-trisubstituted thiosemicarbazide dianion ligands [PDF]

open access: yes, 2003
Reactions of cis-[PtCl₂(PPh₃)₂] or [PdCl₂(PPh₃)₂] with Ph₂N---NHC(S)NHPh and excess triethylamine, in refluxing methanol gave the complexes [M{SC(=NPh)NNPh₂}(PPh₃)₂] containing thiosemicarbazide dianion ligands.
Henderson, William   +1 more
core   +2 more sources

Correlation data of (Z)-1-[4-(trifluoromethyl)benzylidene]thiosemicarbazide via spectroscopic methods and Density Functional Theory studies

open access: yesData in Brief, 2019
New compound, namely (Z)-1-[4-(trifluoromethyl)benzylidene]thiosemicarbazide was successfully synthesized using thiosemicarbazide with 4-(trifluoromethyl)-benzaldehyde in ethanol solution.
Uwaisulqarni M. Osman   +5 more
doaj   +1 more source

Synthesis of Benzimidazole–Based Analogs as Anti Alzheimer’s Disease Compounds and Their Molecular Docking Studies

open access: yesMolecules, 2020
We synthesized 10 analogs of benzimidazole-based thiosemicarbazide 1 (a–j) and 13 benzimidazole-based Schiff bases 2 (a–m), and characterized by various spectroscopic techniques and evaluated in vitro for acetylcholinesterase (AchE) and ...
Bushra Adalat   +8 more
doaj   +1 more source

Pharmacophore Mapping Approach for Drug Target Identification: A Chemical Synthesis and in Silico Study on Novel Thiadiazole Compounds [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Compounds containing thiadiazole moiety are cognized to possess with variety of clinical and therapeutic activity. Finding a suitable drug target for newly synthesized compounds remain a major bottle neck in current high throughout ...
Rohan J. Meshram   +4 more
doaj   +1 more source

Thiosemicarbazide Toxicity in Mice.

open access: yesExperimental Biology and Medicine, 1952
Summary1. Fatal convulsions follow the administration of doses of 20 mg of thiosemicarbazide (TSC)/kg or more to mice. 2. Semicarbazide is approximately 1/20 as toxic as thiosemicarbazide, while aminoguanidine produces no toxic symptoms at a dose of 650 mg/kg. 3.
R E, PARKS, G W, KIDDER, V C, DEWEY
openaire   +2 more sources

Investigation of the effects of magnesium orotate in a model of primary generalized seizures

open access: yesНеврология, нейропсихиатрия, психосоматика, 2017
Objective: to investigate the anticonvulsant and neuroprotective effects of magnesium orotate in a rat thiosemicarbazide model of seizures in rats.Material and methods.
A. G. Kalacheva   +6 more
doaj   +1 more source

Synthesis of Some 1,4-Bis (Substituted 1,3,4-Oxadiazoles and 1,2,4-Triazoles) Benzene From Terephthalic Acid [PDF]

open access: yesمجلة التربية والعلم, 1999
In this paper the synthesis of some 1,4-bis-(substituted1,3,4-oxadiazoles and 1,2,4-trizoles) benzene from terephthalic acid is reported. Terephthalic acid was esterified with absolute ethanol in presence of concentrated sulfuric acid to give ethyl ...
K. Daoud, E. Mahmood, M. Salih
doaj   +1 more source

1,4-disubstituted thiosemicarbazide derivatives are potent inhibitors of toxoplasma gondii proliferation. [PDF]

open access: yes, 2014
A series of 4-arylthiosemicarbazides substituted at the N1 position with a 5-membered heteroaryl ring was synthesized and evaluated in vitro for T. gondii inhibition proliferation and host cell cytotoxicity.
Dzitko, Katarzyna   +6 more
core   +2 more sources

Thiosemicarbazide Derivatives Decrease the ATPase Activity of Staphylococcus aureus Topoisomerase IV, Inhibit Mycobacterial Growth, and Affect Replication in Mycobacterium smegmatis

open access: yesInternational Journal of Molecular Sciences, 2021
Compounds targeting bacterial topoisomerases are of interest for the development of antibacterial agents. Our previous studies culminated in the synthesis and characterization of small-molecular weight thiosemicarbazides as the initial prototypes of a ...
A. Kowalczyk   +5 more
semanticscholar   +1 more source

Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase

open access: yesCroatian Journal of Food Science and Technology, 2017
Inhibitory effect of 32 coumarin derivatives (20 Schiff bases, 5 thiosemicarbazides, 5 thiazolidinones, and their precursors, 7-hydroxy-4-methylcoumarin and 4-methylcoumarin-7-yl hydrazine carboxylate) on partially purified apple polyphenol oxidase was ...
I. Strelec   +4 more
doaj   +1 more source

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