Results 21 to 30 of about 15,360 (269)
Platinum(II), palladium(II) and gold(III) complexes containing 1,1,4-trisubstituted thiosemicarbazide dianion ligands [PDF]
Reactions of cis-[PtCl₂(PPh₃)₂] or [PdCl₂(PPh₃)₂] with Ph₂N---NHC(S)NHPh and excess triethylamine, in refluxing methanol gave the complexes [M{SC(=NPh)NNPh₂}(PPh₃)₂] containing thiosemicarbazide dianion ligands.
Henderson, William +1 more
core +2 more sources
New compound, namely (Z)-1-[4-(trifluoromethyl)benzylidene]thiosemicarbazide was successfully synthesized using thiosemicarbazide with 4-(trifluoromethyl)-benzaldehyde in ethanol solution.
Uwaisulqarni M. Osman +5 more
doaj +1 more source
We synthesized 10 analogs of benzimidazole-based thiosemicarbazide 1 (a–j) and 13 benzimidazole-based Schiff bases 2 (a–m), and characterized by various spectroscopic techniques and evaluated in vitro for acetylcholinesterase (AchE) and ...
Bushra Adalat +8 more
doaj +1 more source
Pharmacophore Mapping Approach for Drug Target Identification: A Chemical Synthesis and in Silico Study on Novel Thiadiazole Compounds [PDF]
Introduction: Compounds containing thiadiazole moiety are cognized to possess with variety of clinical and therapeutic activity. Finding a suitable drug target for newly synthesized compounds remain a major bottle neck in current high throughout ...
Rohan J. Meshram +4 more
doaj +1 more source
Thiosemicarbazide Toxicity in Mice.
Summary1. Fatal convulsions follow the administration of doses of 20 mg of thiosemicarbazide (TSC)/kg or more to mice. 2. Semicarbazide is approximately 1/20 as toxic as thiosemicarbazide, while aminoguanidine produces no toxic symptoms at a dose of 650 mg/kg. 3.
R E, PARKS, G W, KIDDER, V C, DEWEY
openaire +2 more sources
Investigation of the effects of magnesium orotate in a model of primary generalized seizures
Objective: to investigate the anticonvulsant and neuroprotective effects of magnesium orotate in a rat thiosemicarbazide model of seizures in rats.Material and methods.
A. G. Kalacheva +6 more
doaj +1 more source
Synthesis of Some 1,4-Bis (Substituted 1,3,4-Oxadiazoles and 1,2,4-Triazoles) Benzene From Terephthalic Acid [PDF]
In this paper the synthesis of some 1,4-bis-(substituted1,3,4-oxadiazoles and 1,2,4-trizoles) benzene from terephthalic acid is reported. Terephthalic acid was esterified with absolute ethanol in presence of concentrated sulfuric acid to give ethyl ...
K. Daoud, E. Mahmood, M. Salih
doaj +1 more source
1,4-disubstituted thiosemicarbazide derivatives are potent inhibitors of toxoplasma gondii proliferation. [PDF]
A series of 4-arylthiosemicarbazides substituted at the N1 position with a 5-membered heteroaryl ring was synthesized and evaluated in vitro for T. gondii inhibition proliferation and host cell cytotoxicity.
Dzitko, Katarzyna +6 more
core +2 more sources
Compounds targeting bacterial topoisomerases are of interest for the development of antibacterial agents. Our previous studies culminated in the synthesis and characterization of small-molecular weight thiosemicarbazides as the initial prototypes of a ...
A. Kowalczyk +5 more
semanticscholar +1 more source
Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase
Inhibitory effect of 32 coumarin derivatives (20 Schiff bases, 5 thiosemicarbazides, 5 thiazolidinones, and their precursors, 7-hydroxy-4-methylcoumarin and 4-methylcoumarin-7-yl hydrazine carboxylate) on partially purified apple polyphenol oxidase was ...
I. Strelec +4 more
doaj +1 more source

