Evolution of Thiosemicarbazones: From First‐ to Second‐Generation Metal Chelators and Their Reactive Oxygen Species‐Mediated Effects in Melanoma [PDF]
ChemistryOpenWorldwide, melanoma remains a significant public health concern, with an estimated 325,000 new cases and 57,000 deaths recorded in 2020. If current trends persist, these figures are projected to rise to 510,000 new cases and 96,000 deaths annually by ...
Rohina Alim +2 more
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Biomolecules, 2022 In this paper, thiosemicarbazide derivatives were synthesized as potential anticancer agents. X-ray investigations for 1-(2,4-dichlorophenoxy)acetyl-4-(2-fluorophenyl) thiosemicarbazide, 1-(2,4-dichlorophenoxy)acetyl-4-(4-metylothiophenyl ...
Paweł Kozyra +2 more
exaly +4 more sources
Synthesis and Anthelmintic Activity of New Thiosemicarbazide Derivatives—A Preliminary Study
Molecules, 2020 Parasitic infections caused by different species of intestinal helminths still poses a threat to public health. There is a need to search for new, effective anthelmintic drugs. A series of novel thiosemicarbazides were synthesized and evaluated for their
Katarzyna Dziduch +2 more
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Effects of a Thiosemicarbazide Camphene Derivative on Trichophyton mentagrophytes
Molecules, 2009 Thiosemicarbazides are compounds known for their biological activity, particularly their antimicrobial properties, which include activity against fungi.
Tania Ueda-Nakamura +2 more
exaly +4 more sources
THE ANTI-NEOPLASTIC ACTIVITY OF THE COORDINATIVE COMPOUNDS, THIOSEMICARBAZIDE DERIVATES [PDF]
Arta Medica, 2023 Background. Thiosemicarbazide derivates are considered potential compounds of the antitumor drugs, with a large spectrum of biological properties. The aim of the research was to reflect the actual progress in studies on thiosemicarbazide derivates ...
Valeriana Pantea, Evelina Lesnic
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Anticancer Activity and Safety Profile of Novel 1-(4-Fluorophenoxyacetyl)-4-substituted Thio/Semicarbazide Derivatives [PDF]
MoleculesCompounds with thiosemicarbazide and semicarbazide scaffolds are among the most promising structures in medicinal chemistry due to the possibility of forming multiple hydrogen bonds.
Paweł Kozyra +7 more
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From Design to Bioactivity: 2-Benzoylpyridine 4-(bicyclo[2.2.1]hept-2-yl)thiosemicarbazone and Its 3d Metal Coordination Compounds. [PDF]
ChemistryOpenThe new 2‐benzoylpyridine 4‐(bicyclo[2.2.1]hept‐2‐yl)thiosemicarbazone (HL) and its copper(II), nickel(II), cobalt(III), and iron(III) coordination compounds [Cu(L)Cl] (1), [Cu(L)NO3] (2), {[Cu(L)(Cl2CHCOO)]}n (3), [Ni(HL)2](NO3)2 (4), [Fe(L)2]NO3 (5), [Co(L)2]NO3 (6) were obtained.
Graur I +6 more
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Preparation of new Schiff bases based on thiosemicarbazide and evaluation of their inhibitory properties on corrosion of carbon steel in acidic environment [PDF]
شیمی کاربردی روز, 2023 In this work, two Schiff bases named 1-(2-hydroxybenzylidene)-4-phenylthiosemicarbazide (2-HTSC) and 1-(3-hydroxybenzylidene)-4-phenylthiosemicarbazide (3-HTSC) were synthesized and evaluated their inhibitory properties on corrosion of carbon steel in 15%
Homayoon Eslamizadeh +2 more
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Synthesis of Some 1,4-Bis (Substituted 1,3,4-Oxadiazoles and 1,2,4-Triazoles) Benzene From Terephthalic Acid [PDF]
مجلة التربية والعلم, 1999 In this paper the synthesis of some 1,4-bis-(substituted1,3,4-oxadiazoles and 1,2,4-trizoles) benzene from terephthalic acid is reported. Terephthalic acid was esterified with absolute ethanol in presence of concentrated sulfuric acid to give ethyl ...
K. Daoud, E. Mahmood, M. Salih
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Synthesis and Characterization of the Triazole Derived from Thiosemicarbazide, 4-Amino-5-Phenyl-4H-1,2,4- Triazole-3-Thiol and Their Copper(II) and Nickel(II) Complexes [PDF]
Engineering and Technology Journal, 2013 Triazole N-(3-mercapto-5-phenyl-4H-1,2,4-triazol-4-yl)hydrazinecarbothioamide prepared in good yield via the condensation of 4-amino-5-phenyl-4H-1,2,4-triazole-3-thiol and thiosemicarbazide.
Hamdan Abood Aday
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