Tripeptides conjugated with thiosemicarbazones: new inhibitors of tyrosinase for cosmeceutical use
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 The development of skin-care products is recently growing. Cosmetic formulas containing active ingredients with proven efficacy, namely cosmeceuticals, are based on various compounds, including peptides.
Patrycja Ledwoń +8 more
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Trypanotoxic activity of thiosemicarbazone iron chelators. [PDF]
, 2015 Only a few drugs are available for treating sleeping sickness and nagana disease; parasitic infections caused by protozoans of the genus Trypanosoma in sub-Saharan Africa.
Ellis, S, Sexton, DW, Steverding, D
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The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms [PDF]
, 2016 Background Neuroblastoma is a relatively common and highly belligerent childhood tumor with poor prognosis by current therapeutic approaches. A novel anti-cancer agent of the di-2-pyridylketone thiosemicarbazone series, namely di-2-pyridylketone 4,4 ...
Danuta S. Kalinowski +5 more
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A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds
Journal of New Results in ScienceThiosemicarbazones can be synthesized by condensation of thiosemicarbazides with ketones or aldehydes and play a role as precursors in the synthesis of many compounds such as thiazoles.
Gürsel Korkmaz
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Thiosemicarbazone organocatalysis:Tetrahydropyranylation and 2-deoxygalactosylation reactions and kinetics-based mechanistic investigation [PDF]
, 2017 Thiosemicarbazones are introduced as a new class of highly tunable and efficient organocatalysts. We showcase this by studies of the tetrahydropyranylation reaction, where insights to the mechanism was achieved by a double Hammett analysis of both the ...
Akselsen, Olivia M. +4 more
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COMPUȘI COORDINATIVI AI CUPRULUI(II) CU TIOSEMICARBAZONE ALE 2-FORMILPIRIDINEI ȘI DERIVAȚILOR EI
Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2021 În articol este efectuată analiza literaturii de specialitate privind sinteza, caracterizarea structurală și proprietățile biologice ale compușilor coordinativi ai cuprului(II) în baza tiosemicarbazonelor 2-formilpiridinei și a derivaților ei.
Elena NEGUȚA
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Crystals, 2022 The new ligand HMeATSM, derived from condensation of 2-3-butanedione with 4-methyl-3-thiosemicarbazide and 2,4-dimethyl-3-thiosemicarbazide, has been synthesized.
Luis Alonso +3 more
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Design, synthesis and biological evaluation of thiosemicarbazones, hydrazinobenzothiazoles and arylhydrazones as anticancer agents with a potential to overcome multidrug resistance [PDF]
, 2016 There is a constant need for new therapies against multidrug resistant (MDR) cancer. An attractive strategy is to develop chelators that display significant antitumor activity in multidrug resistant cancer cell lines overexpressing the drug efflux pump P-
Füredi, András +5 more
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IN VITRO study of copper coordination compounds with thiosemicarbazone action on antioxidant enzymes
One Health & Risk ManagementIntroduction. Thiosemicarbazones represent a class of organic compounds with significant pharmacological potential, known for their antitumor, antimicrobial, and antiviral activities.
Valeriana PANTEA +4 more
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Efficient eco-friendly syntheses of dithiocarbazates and thiosemicarbazones
Green Chemistry Letters and Reviews, 2020 Eight Schiff bases have been synthesized by conventional and three different eco-friendly methods, whereby two aromatic carbonyl compounds viz.
Nur Halilatul Sadiqin O. Ali +8 more
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