Results 41 to 50 of about 7,220 (228)

Thiosemicarbazone organocatalysis:Tetrahydropyranylation and 2-deoxygalactosylation reactions and kinetics-based mechanistic investigation [PDF]

, 2017
Thiosemicarbazones are introduced as a new class of highly tunable and efficient organocatalysts. We showcase this by studies of the tetrahydropyranylation reaction, where insights to the mechanism was achieved by a double Hammett analysis of both the ...
Akselsen, Olivia M., Langhorn, Line M., Larsen, Dennis, Nielsen, Bjarne E., Pittelkow, Michael   +4 more
core   +2 more sources

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

Benzoin thiosemicarbazone

Acta Crystallographica Section E Structure Reports Online, 2005
In the title compound, C15H15N3OS, the thio­semicarbazone moiety is planar, with a maximum deviation of 0.0369 (11) A, and has an E configuration. The planar phenyl rings make dihedral angles of 26.56 (9) and 81.20 (5)° with the plane of the thio­semicarbazone moiety. In the mol­ecule, there are two intramolecular interactions of types N—H⋯O and N—H⋯N.
Dincer, M, Ozdemir, N, Cukurovali, A, Yilmaz, I   +3 more
openaire   +2 more sources

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Avaliação do potencial anticorrosivo de tiossemicarbazonas solubilizadas em microemulsão

Química Nova, 2013
In this paper, thiosemicarbazones 4-N-cinnamoyl-thiosemicarbazone (CTSC), 4-N-(2'-methoxycinnamoyl)-thiosemicarbazone (MCTSC), and 4-N-(4'-hydroxy-3'-methoxybenzoyl)- thiosemicarbazone (HMBTSC) were solubilized in an oil-in-water (O/W) microemulsion ...
Elaine Cristina M. de Moura, Adna Dornelles N. Souza, Cátia Guaraciara F. T. Rossi, Djalma R. da Silva, Maria Aparecida M. Maciel, Aurea Echevarria, Myrtes S. S. Bellieny   +6 more
doaj   +1 more source

Daganatos sejtek rezisztenciáját gátló vegyületek fejlesztése = Development of compounds targeting multidrug resistant cancer [PDF]

, 2009
A korszerű daganatellenes terápia jelentős sikerei ellenére a kemoterápiával szemben fellépő rezisztencia (multidrog rezisztencia, MDR) továbbra is megoldásra váró klinikai kihívás.
Szakács, Gergely
core  

Palladium(II) and platinum(II) bis(thiosemicarbazone) complexes of the 2,6-diacetylpyridine series with high cytotoxic activity in cisplatin resistant A2780cisR tumor cells and reduced toxicity [PDF]

, 2013
NOTICE: this is the author’s version of a work that was accepted for publication in Journal of Inorganic Biochemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Leitão, Inês, Matesanz, Ana I., Souza, Pilar   +2 more
core   +2 more sources

Potential Biological Targets of Anticancer Metal‐Based Drug Candidates: A Systematic Review

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT The discovery of Cisplatin marked the beginning of the metallodrug era in oncology. Despite their clinical success, platinum‐based compounds present important limitations, including drug resistance and systemic toxicity. These challenges have stimulated interest in alternative metal complexes capable of interacting with biomolecular targets ...
Allysson L. dos S. Ferreira, Bruna B. Dantas, Jailton De Souza‐Ferrari, Edilson B. Alencar Filho   +3 more
wiley   +1 more source

Complexes of 3dn Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity

Molecules, 2007
The chelating behavior of the thiosemicarbazone derivatives of 2-hydroxy-8-R-tricyclo[7.3.1.0.2,7]tridecane-13-one (where R = H, CH3, C6H5) towards Co(II), Ni(II) and Cu(II) has been investigated by elemental analysis, molar conductivity measurements, UV-
Tudor Rosu, Aurelian Gulea, Anca Nicolae, Rodica Georgescu   +3 more
doaj   +1 more source

Synthesis, characterization, antibacterial activity of thiosemicarbazones derivatives and their computational approaches: Quantum calculation, molecular docking, molecular dynamic, ADMET, QSAR

Heliyon, 2023
The thiosemicarbazones and their derivatives have been recognized as antimicrobial agents against human pathogenic bacteria and fungi. Regarding these prospective, this study was designed to address the new antimicrobial agents from thiosemicarbazones ...
Mahbub Alam, Mohammed Nurul Abser, Ajoy Kumer, Md Mosharef Hossain Bhuiyan, Parul Akter, Md Emdad Hossain, Unesco Chakma   +6 more
doaj   +1 more source