Results 31 to 40 of about 2,427 (174)

Synthesis and Toxicity Evaluation of Some N4-Aryl Substituted 5-Trifluoromethoxyisatin-3-thiosemicarbazones

Molecules, 2011
A series of twenty one N4-aryl substituted 5-trifluoromethoxyisatin-3-thiosemicarbazones 3a-3u was synthesized by the reaction of trifluoromethoxyisatin 1 with different arylthiosemicarbazides 2 in aqueous ethanol (50%), containing a few drops of acetic ...
Muhammad Yaqub, Mohammad Saeed Iqbal, Humayun Pervez, Naveeda Saira, Khalid Mohammed Khan   +4 more
doaj   +1 more source

Hematite (α‐Fe2O3) Nanoparticles Conjugated with Thiosemicarbazones: Hydrothermal‐Assisted Synthesis, Characterization, Antibacterial, Antioxidant, and Photocatalytic Activities [PDF]

Chem Biodivers
The study describes the functionalization of α‐Fe2O3 nanoparticles with three different thiosemicarbazone ligands through a hydrothermal route. The nanoconjugates were tested for their antibacterial and antioxidant activities, and their photocatalytic potential was tested against malachite green dye.
Veg E, Dwivedi S, Rai S, Sharma S, Fatima N, Joshi S, Khan A, Khan T.   +7 more
europepmc   +2 more sources

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Avaliação do potencial anticorrosivo de tiossemicarbazonas solubilizadas em microemulsão

Química Nova, 2013
In this paper, thiosemicarbazones 4-N-cinnamoyl-thiosemicarbazone (CTSC), 4-N-(2'-methoxycinnamoyl)-thiosemicarbazone (MCTSC), and 4-N-(4'-hydroxy-3'-methoxybenzoyl)- thiosemicarbazone (HMBTSC) were solubilized in an oil-in-water (O/W) microemulsion ...
Elaine Cristina M. de Moura, Adna Dornelles N. Souza, Cátia Guaraciara F. T. Rossi, Djalma R. da Silva, Maria Aparecida M. Maciel, Aurea Echevarria, Myrtes S. S. Bellieny   +6 more
doaj   +1 more source

Synthesis, Moleculer Modeling, and Carbonic Anhydrase Inhibitor Effects of Novel 1‐(1‐benzyl‐2‐oxoindolin‐3‐ylidene)‐4‐(3‐sulfamoylphenyl)thiosemicarbazides

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Novel 1‐(1‐benzyl‐2‐oxoindolin‐3‐ylidene)thiosemicarbazides (6a–l) bearing a 3‐sulfamoylphenyl moiety selectively inhibited the tumor‐associated hCA IX and XII isoforms over hCA I and II isoforms at the nanomolar levels. Compounds 6k and 6f emerged as the most potent inhibitors of hCA IX and XII, respectively.
Çağla Begüm Apaydın, Tuğçe Cinek, Hayrunnisa Nadaroğlu, Nilgün Karalı   +3 more
wiley   +1 more source

Complexes of 3dn Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity

Molecules, 2007
The chelating behavior of the thiosemicarbazone derivatives of 2-hydroxy-8-R-tricyclo[7.3.1.0.2,7]tridecane-13-one (where R = H, CH3, C6H5) towards Co(II), Ni(II) and Cu(II) has been investigated by elemental analysis, molar conductivity measurements, UV-
Tudor Rosu, Aurelian Gulea, Anca Nicolae, Rodica Georgescu   +3 more
doaj   +1 more source

Thiosemicarbazones with tyrosinase inhibitory activity [PDF]

MedChemComm, 2019
Thiosemicarbazones reveal strong anti-tyrosinase activity.
Katarzyna Hałdys, Rafał Latajka
openaire   +2 more sources

Diethylene Glycol‐Linked Ring‐Fused Bis‐Azoles: Target‐Oriented Synthesis, In Silico Screening, and Antitumor Activity

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
A series of diethylene glycol‐linked cyclic derivatives with diversity in the heterocyclic motif have been synthesized and screened for antitumor activity. Two bis‐thiazolo[3,2‐a]pyrimidinone derivatives displayed moderate cytotoxicity, high selectivity against hepatocellular carcinoma cells, promising VEGFR2, and remarkable FGFR2 inhibitory activities
Sami A. Al‐Hussain, Abdulrahman S. Alharbi, Zeinab A. Muhammad, Alyaa S. Abdel Halim, Magdi E. A. Zaki, Mark C. Bagley, Refaie M. Kassab   +6 more
wiley   +1 more source

Recent Advances in Chemosensors Bearing Pyrazole and Imidazole Rings: An Approach Toward the Detection of Metal Ions Based on these Diazoles

Advanced Sensor Research, Volume 5, Issue 10, October 2026.
This contribution analyzes recent articles (2021–2025) on chemosensors containing pyrazole and imidazole rings for detecting metal ions, using distinctive examples. It focuses on the structural design of probes, their coordination behavior, sensing mechanisms, and analytical performance, including selectivity, sensitivity, working wavelength, and ...
Alexander Ladino‐Bejarano, Carlos Cifuentes, Néstor Bravo, Jaime Portilla   +3 more
wiley   +1 more source

Synthetic Strategy to Novel Highly Functionalized Furan Analogues Bearing Imidazole–Thiazole Hybrids: Structural Characterization, Nanoparticle Formulations, Antimicrobial Evaluation, Molecular Docking Studies, and Molecular Dynamic Simulations

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
A novel highly functionalized furan analogues bearing imidazole–thiazole hybrids were prepared via efficient synthetic routes. Selected compounds were formulated into nanoparticle systems. Antimicrobial evaluation for all synthesized compounds and nanoformulations was evaluated against a panel of bacterial strains.
Ashraf A. Sediek, Azza A. kamel, Ola M. El‑Borady, Ahmed F. El‐Sayed, Ahmed A. El‐Rashedy, Eman Sabry   +5 more
wiley   +1 more source