Results 31 to 40 of about 4,853 (201)

The phosphinoboration of thiosemicarbazones

Canadian Journal of Chemistry, 2023
This study reports on the exploration of the phosphinoboration reaction with several thiosemicarbazones (R5R4NC(S)NR3N=CR1R2). Reactions between either Ph2PBpin (pin = 1,2-O2C2Me4) or Ph2PBcat (cat = 1,2-O2C6H4) with thiosemicarbazones containing a terminal primary or secondary amine afforded boron-containing heterocyclic 1,3,4-thiadiazoline products ...
Samuel R. Baird, Christopher M. Vogels, Stephen J. Geier, Lara K. Watanabe, Justin F. Binder, Charles L. B. Macdonald, Stephen A. Westcott   +6 more
openaire   +2 more sources

Steric Blockade of Oxy-Myoglobin Oxidation by Thiosemicarbazones: Structure–Activity Relationships of the Novel PPP4pT Series

, 2023
The di-2-pyridylketone thiosemicarbazones demonstrated marked anticancer efficacy, prompting progression of DpC to clinical trials. However, DpC induced deleterious oxy-myoglobin oxidation, stifling development.
Bernhardt, Paul V, Gholam Azad, Mahan, Richardson, Des R., Wijesinghe, Tharushi P, Bernhardt, Paul V., Gonzálvez, Miguel A, Wijesinghe, Tharushi P., Harmer, Jeffrey R, Gonzalvez, Miguel A., Kaya, Busra, Dharmasivam, Mahendiran, Richardson, Des R, Harmer, Jeffrey R.   +12 more
core   +1 more source

A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds

Journal of New Results in Science
Thiosemicarbazones can be synthesized by condensation of thiosemicarbazides with ketones or aldehydes and play a role as precursors in the synthesis of many compounds such as thiazoles.
Gürsel Korkmaz
doaj   +1 more source

Synthesis, characterization, antibacterial activity of thiosemicarbazones derivatives and their computational approaches: Quantum calculation, molecular docking, molecular dynamic, ADMET, QSAR

Heliyon, 2023
The thiosemicarbazones and their derivatives have been recognized as antimicrobial agents against human pathogenic bacteria and fungi. Regarding these prospective, this study was designed to address the new antimicrobial agents from thiosemicarbazones ...
Mahbub Alam, Mohammed Nurul Abser, Ajoy Kumer, Md Mosharef Hossain Bhuiyan, Parul Akter, Md Emdad Hossain, Unesco Chakma   +6 more
doaj   +1 more source

Synthesis, characterization and antiproliferative activity of hexa arm star shaped thiosemicarbazones derived from cyclotriphosphazene core

, 2014
A series of novel hexa-arm star shaped thiosemicarbazones with different substitutions at para positions emanating from cyclotriphosphazene core were prepared with excellent yields.
Patil, B.R., Machakanur, S.S., Bakale, R.P., Naik, G.N., Bligh, S.W.A., Gudasi, K.B.   +5 more
core   +1 more source

COMPUȘI COORDINATIVI AI CUPRULUI(II) CU TIOSEMICARBAZONE ALE 2-FORMILPIRIDINEI ȘI DERIVAȚILOR EI

Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2021
În articol este efectuată analiza literaturii de specialitate privind sinteza, caracterizarea structurală și proprietățile bio­lo­gice ale compușilor coordinativi ai cuprului(II) în baza tiosemicarbazonelor 2-formilpiridinei și a derivaților ei.
Elena NEGUȚA
doaj  

Tripeptides conjugated with thiosemicarbazones: new inhibitors of tyrosinase for cosmeceutical use

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
The development of skin-care products is recently growing. Cosmetic formulas containing active ingredients with proven efficacy, namely cosmeceuticals, are based on various compounds, including peptides.
Patrycja Ledwoń, Waldemar Goldeman, Katarzyna Hałdys, Michał Jewgiński, Greta Calamai, Joanna Rossowska, Anna Maria Papini, Paolo Rovero, Rafał Latajka   +8 more
doaj   +1 more source

IN VITRO study of copper coordination compounds with thiosemicarbazone action on antioxidant enzymes

One Health & Risk Management
Introduction. Thiosemicarbazones represent a class of organic compounds with significant pharmacological potential, known for their antitumor, antimicrobial, and antiviral activities.
Valeriana PANTEA, Ecaterina PAVLOVSCHI, Silvia STRATULAT, Olga TAGADIUC, Valentin GUDUMAC   +4 more
doaj   +1 more source

Synthesis and NMR Characterization of New Thiosemicarbazones

, 2020
Isatin Thiosemicarbazones have been shown to have medicinal applications, including anti-tuberculosis drugs. Recently, our lab has shown that Palladium complexes of these same isation thiosemicarbazones strongly inhibit the Topoisomerase ...
Frost, Ella
core   +1 more source

Potential leishmanicidal of the thiosemicarbazones: A review

Results in Chemistry
Thiosemicarbazones constitute a class of organic compounds with the general structure R=N-NH-CS-NHR and are known for their biological properties, making them an important structure for drug development. This work presents a systematic review of the main
Edilane Almeida da Silva, Ismael Holanda do Vale, Elizabete Silva Sousa, Sidney Silva Simplicio, Arlan de Assis Gonsalves, Cleônia Roberta Melo Araújo   +5 more
doaj   +1 more source