Synthesis, Crystal Structure, Antioxidant, Antimicrobial, and Mutagenic Activities and DNA Interaction Studies of Ni(II) Schiff Base 4-Methoxy-3-Benzyloxybenzaldehyde Thiosemicarbazide Complexes [PDF]
, 2013 Three new Ni(II) square planar complexes of 4-methoxy-3-benzyloxybenzaldehyde thiosemicarbazide(4m3BTSC) having polypyridyl bases of general formulation [ML2] (1) and [MLB] (2, 3), where L = 4m3BTSC and B is N,N-donor heterocyclic bases, namely, 1,10 ...
Aradhya, M.S. +5 more
core +1 more source
Thiosemicarbazones active against Clostridium difficile [PDF]
Bioorganic & Medicinal Chemistry Letters, 2008 A set of closely related furylidene thiosemicarbazones was prepared and screened against various clinically important Gram-positive bacteria. One compound containing an ethylene spacer and a 5-nitrofuryl group was found to have promising activity against Clostridium difficile.
Costello, Cait +8 more
openaire +2 more sources
Potential leishmanicidal of the thiosemicarbazones: A review
Results in ChemistryThiosemicarbazones constitute a class of organic compounds with the general structure R=N-NH-CS-NHR and are known for their biological properties, making them an important structure for drug development. This work presents a systematic review of the main
Edilane Almeida da Silva +5 more
doaj +1 more source
Molecules, 2011 A series of twenty one N4-aryl substituted 5-trifluoromethoxyisatin-3-thiosemicarbazones 3a-3u was synthesized by the reaction of trifluoromethoxyisatin 1 with different arylthiosemicarbazides 2 in aqueous ethanol (50%), containing a few drops of acetic ...
Muhammad Yaqub +4 more
doaj +1 more source
Pharmacological and Structure-Activity Relationship Evaluation of 4-aryl-1-Diphenylacetyl(thio)semicarbazides [PDF]
, 2014 This article describes the synthesis of six 4-aryl-(thio)semicarbazides (series a and b) linked with diphenylacetyl moiety along with their pharmacological evaluation on the central nervous system in mice and computational studies, including ...
Fidecka, Sylwia +8 more
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Thiosemicarbazones with tyrosinase inhibitory activity [PDF]
MedChemComm, 2019 Thiosemicarbazones reveal strong anti-tyrosinase activity.
Katarzyna Hałdys, Rafał Latajka
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Organometallic gold(III) complexes with tridentate halogen‐substituted thiosemicarbazones: Effects of halogenation on cytotoxicity and anti‐parasitic activity [PDF]
, 2019 Chemical properties and biological activity of Au(III) compounds obtained from dichlorido[2‐(dimethylaminomethyl)phenyl‐C1,N]gold(III), [Au(damp‐C1,N)Cl2], and halogenated, potentially tridentate thiosemicarbazones have been studied.
Abram, Ulrich +7 more
core +1 more source
Avaliação do potencial anticorrosivo de tiossemicarbazonas solubilizadas em microemulsão
Química Nova, 2013 In this paper, thiosemicarbazones 4-N-cinnamoyl-thiosemicarbazone (CTSC), 4-N-(2'-methoxycinnamoyl)-thiosemicarbazone (MCTSC), and 4-N-(4'-hydroxy-3'-methoxybenzoyl)- thiosemicarbazone (HMBTSC) were solubilized in an oil-in-water (O/W) microemulsion ...
Elaine Cristina M. de Moura +6 more
doaj +1 more source
Unprecedented Pt(II) complex of an asymmetric 2,6-diacetylpyridine bis(4N-substituted thiosemicarbazone) ligand [PDF]
, 2013 NOTICE: this is the author’s version of a work that was accepted for publication in Inorganic Chemistry Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Matesanz, Ana I., Souza, Pilar
core +2 more sources
Journal of Applied Polymer Science, Volume 143, Issue 4, January 20, 2026.ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares +4 more
wiley +1 more source