Results 61 to 70 of about 14,165 (252)
Synthesis, Crystal Structural Investigations, and DFT Calculations of Novel Thiosemicarbazones
The crystal and molecular structures of three new thiosemicarbazones, 2-[1-(2-hydroxy-5-methoxyphenyl)ethylidene]-N-methyl-hydrazinecarbothioamide monohydrate (1), 2-[1-(2-hydroxy-5-methoxyphenyl)ethylidene]-N-ethyl-hydrazinecarbothioamide (2) and 2-[1 ...
Brian J. Anderson +5 more
doaj +1 more source
Daganatos sejtek rezisztenciáját gátló vegyületek fejlesztése = Development of compounds targeting multidrug resistant cancer [PDF]
A korszerű daganatellenes terápia jelentős sikerei ellenére a kemoterápiával szemben fellépő rezisztencia (multidrog rezisztencia, MDR) továbbra is megoldásra váró klinikai kihívás.
Szakács, Gergely
core
Synthesis and structural characterization of a disulphide-bridged tetranuclear palladium(II) complex derived from 3,5-diacetyl 1,2,4-triazole bis(4-ethylthiosemicarbazone) [PDF]
NOTICE: this is the author’s version of a work that was accepted for publication in Inorganic Chemistry Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Matesanz, Ana I. +2 more
core +2 more sources
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct‐acting poxvirus inhibitors and host‐directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and ...
Leilei ZHAO +7 more
wiley +1 more source
Investigation of the Biological Properties of (Hetero)Aromatic Thiosemicarbazones
Two series of thiosemicarbazone-based iron chelators (twenty-seven compounds) were designed and synthesized using a microwave-assisted approach. Quinoline and halogenated phenyl were selected as parent scaffolds on the basis of a similarity search.
Jaroslaw Polanski +8 more
doaj +1 more source
Organometallic Ruthenium Complexes of Novel Thiosemicarbazones [PDF]
We present the preliminary results of a study of two novel thiosemicarbazones (TSCs) and theirruthenium complexes. The TSCs were prepared by refluxing thiosemicarbazide with 9-anthraldehyde or benzanthrone in ethanol for 3 hours.
Beckford, Floyd A., Holt, Amon T.
core +1 more source
A library of cationic dinuclear Ru(II)‐η⁶‐arene analogues was developed to assess how overall charge and Ru–Ru distance influence DNA binding noncovalent interactions and cytotoxicity. NMR studies showed multiple binding modes with the B‐form DNA oligonucleotide d(5΄‐CGCGAATTCGCG‐3΄)2, while the complexes displayed micromolar IC50 values against MCF‐7,
Dimitrios Thomos +5 more
wiley +1 more source
A novel two tri-thiosemicarbazones derivatives, namely 2,2',2''-((2-Hydroxybenzene-1,3,5-triyl)tris(methanylylidene))tris(N-benzylhydrazine-1-carbothioamide) (HBC) and 2,2',2''-((2-hydroxybenzene-1,3,5-triyl) tris (methanylylidene)) tris (N ...
Ahmed M. Abuelela +7 more
doaj +1 more source
Introduction. The increasing number of cancer diagnoses is a pressing issue in modern medicine. One contributing factor to cancer development is oxidative stress caused by free radicals, which can damage proteins, lipids, and DNA.
Andrei CIURSIN +2 more
doaj +1 more source
New imidazole derived thiosemicarbazones and hydrazones were prepared by condensation of 4(5)-imidazole carboxaldehyde, 4-(1H-imidazole-1-yl)benzaldehyde and 4-(1H-imidazole-1-yl)acetophenone with a thiosemicarbazide or hydrazide.
Jacqueline A. Takahashi +7 more
doaj +1 more source

