Results 71 to 80 of about 14,165 (252)

Transalkylidation reaction: green, catalyst-free synthesis of thiosemicarbazones and solving the NMR conflict between their acyclic structure and intramolecular cycloaddition products

open access: yesGreen Chemistry Letters and Reviews, 2019
A series of arylidene thiosemicarbazides have been prepared by a new method, which was titled as transalkylidation. This method is an effective, fast, green and clean method. The mechanism of this reaction has been discussed.
Mohamed A. El-Atawy   +3 more
doaj   +1 more source

New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis

open access: yesMolecules, 2019
Co-infection of malaria and tuberculosis, although not thoroughly investigated, has been noted. With the increasing prevalence of tuberculosis in the African region, wherein malaria is endemic, it is intuitive to suggest that the probability of co ...
Richard M. Beteck   +6 more
doaj   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade   +4 more
wiley   +1 more source

Structural Studies of 2,6-Diacetyl- and 2,6-Diformylpyridine Bis(thiosemicarbazones)

open access: yesJournal of the Brazilian Chemical Society, 2002
Although a large number of crystal structures of heterocyclic thiosemicarbazones have recently appeared in the literature, few structures of heterocyclic bis(thiosemicarbazones) or their metal complexes have been reported.
Brown Christine A.   +4 more
doaj  

Synthesis, Characterization, Crystal Structures and Urease Inhibition of Thiosemicarbazones

open access: yesActa Chimica Slovenica
Thiosemicarbazones are biological active compounds. Six new thiosemicarbazones were prepared and structurally characterized by elemental analysis, 1H NMR and IR spectra, as well as single crystal X-ray diffraction.
Ling-Wei Xue, Qiao-Ru Liu, Yong-Jun Han
doaj   +1 more source

Palladium(II) and platinum(II) bis(thiosemicarbazone) complexes of the 2,6-diacetylpyridine series with high cytotoxic activity in cisplatin resistant A2780cisR tumor cells and reduced toxicity [PDF]

open access: yes, 2013
NOTICE: this is the author’s version of a work that was accepted for publication in Journal of Inorganic Biochemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Leitão, Inês   +2 more
core   +2 more sources

Design, Synthesis, In Silico Absorption, Distribution, Metabolism, and Elimination and Molecular Docking Studies of Thiazole‐Based Furan Derivatives, and Their Biological Evaluation for Alzheimer Disease Therapy

open access: yesChemistryOpen, Volume 14, Issue 12, December 2025.
GA: Oxidative stress plays a critical role in Alzheimer's disease (AD) by promoting Aβ plaque accumulation and tau pathology, accelerating neurodegeneration. Elevated reactive oxygen species contribute to cognitive decline through extensive oxidative damage.
Abdüllatif Karakaya   +8 more
wiley   +1 more source

Synthesis of thiosemicarbazone derivatives and evaluation of their cytotoxicity with emphasis on ferroptosis biomarkers; an in vitro study

open access: yesResearch in Pharmaceutical Sciences
Background and purpose: This study aimed to evaluate the cytotoxicity of synthesized thiosemicarbazone derivatives, particularly on biomarkers associated with ferroptosis.
Yasaman Shadmani   +4 more
doaj   +1 more source

CHARACTERIZATION AND ANTIPARASITIC ACTIVITY OF BENZOPHENONE THIOSEMICARBAZONES ON Trypanosoma brucei brucei [PDF]

open access: yes, 2011
The structure of four synthesized thiosemicarbazones, substituted or not, of benzophenone has been confirmed by spectrometrical analysis IR, NMR 1H and 13C. Their anti-trypanosomal activities were evaluated on Trypanosoma brucei brucei.
Bienvenu Glinma   +5 more
core  

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