Results 171 to 180 of about 1,856 (207)

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

Tuning Redox Dynamics in Cu‐Based Electrocatalysts: Effect of Secondary Metals

Advanced Functional Materials, EarlyView.
Advanced analysis of operando X‐ray absorption spectroscopy data reveals that secondary metals affect the redox processes in Cu‐based catalysts for electrocatalytic CO2 reduction. This influences the amount of oxides formed under pulsed reaction conditions and the distribution of reaction products.
Martina Rüscher, Andrea Martini, Eduardo Ortega, Lichen Bai, Eric Liberra, Daniel Escalera‐López, Hyo Sang Jeon, Antonia Herzog, Clara Rettenmaier, Dorottya Hursán, David Koshy, Mariana Cecilio de Oliveira Monteiro, Timon Wagner, Leon Jacobse, Felix Haase, Arno Bergmann, Janis Timoshenko, Beatriz Roldan Cuenya   +17 more
wiley   +1 more source

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Third-generation sequencing for genetic disease

Clinica Chimica Acta, 2023
Third-generation sequencing (TGS) has led to a brave new revolution in detecting genetic diseases over the last few years. TGS has been rapidly developed for genetic disease applications owing to its significant advantages such as long read length, rapid detection, and precise detection of complex and rare structural variants.
Xiaoting Ling, Chenghan Wang, Linlin Li, Liqiu Pan, Chaoyu Huang, Caixia Zhang, Yunhua Huang, Yuling Qiu, Faquan Lin, Yifang Huang   +9 more
openaire   +2 more sources

Quality of Third Generation Sequencing

Journal of Computational and Theoretical Nanoscience, 2020
Third generation sequencing (TGS) relates to long reads but with relatively high error rates. Quality of TGS is a hot topic, dealing with errors. This paper combines and investigates three quality related metrics. They are basecalling accuracy, Phred Quality Scores, and GC content. For basecalling accuracy, a deep neural network is adopted.
Ali Elbialy, M. A. El-Dosuky, Ibrahim M. El-Henawy   +2 more
openaire   +1 more source

Full-Length Transcript Phasing with Third-Generation Sequencing

2022
Haplotyping individual full-length transcripts can be important in diagnosis and treatment of certain genetic diseases. One set of diseases, repeat expansions of simple tandem repeat sequences are the cause of over 40 neurological disorders. In many of these conditions, expanding a polymorphic repeat beyond a given threshold has been strongly ...
Nenad, Svrzikapa, Ramakrishna, Boyanapalli   +1 more
openaire   +2 more sources

Nanopore Third-Generation Sequencing for Comprehensive Analysis of Hemoglobinopathy Variants

Clinical Chemistry, 2023
Abstract Background Oxford Nanopore Technology (ONT) third-generation sequencing (TGS) is a versatile genetic diagnostic platform. However, it is nonetheless challenging to prepare long-template libraries for long-read TGS, particularly the ONT method for analysis of hemoglobinopathy variants ...
Weilun Huang, Shoufang Qu, Qiongzhen Qin, Xu Yang, Wanqing Han, Yongli Lai, Jiaqi Chen, Shihao Zhou, Xuexi Yang, Wanjun Zhou   +9 more
openaire   +2 more sources

A crowdsourcing method for correcting sequencing errors for the third-generation sequencing data

2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2017
The third generation sequencing data exposes great advantage on read length, which extremely benefits the genomic analyses. However, the third generation sequencing data implies error models different from the ones that the second generation data brings.
Yu Geng 0001, Zhongmeng Zhao, Zhaofang Du, Yixuan Wang, Tian Zheng, Siyu He, Xuanping Zhang, Jiayin Wang   +7 more
openaire   +1 more source

Third Generation DNA Sequencing with a Nanopore

2011
With the advent of Next-Generation-Sequencing (NGS) technologies, an enormous volume of DNA sequencing data can be generated at low cost, placing genomic science within the grasp of everyday medicine. However, mired in this voluminous data, a new problem has emerged: the assembly of the genome from the short reads.
Gregory Timp, Utkur Mirsaidov, Winston Timp, Jiwook Shim, Deqiang Wang, Valentin Dimitrov, Jan Scrimgeour, Chunchen Lin, Jeffrey Comer, Anthony H. Ho, Xueqing Zou, Aleksei Aksimentiev, Klaus Schulten   +12 more
openaire   +1 more source

Enhancing Thalassemia Diagnosis: Advantages of Third-Generation Sequencing

Clinical Laboratory
This study aimed to evaluate the efficacy of third-generation sequencing (TGS) and a thalassemia (Thal) gene diagnostic kit in identifying Thal gene mutations.Blood samples (n = 119) with positive hematology screening results were tested using polymerase chain reaction (PCR)-based methods and TGS on the PacBio-Sequel-II-platform, respectively.Out of ...
Minjun, Huang, Jiexiang, Huang, Liumin, Yu, Kun, Lin   +3 more
openaire   +2 more sources

DNA Sequencing and the Third-Generation Sequencing Revolution

Since the discovery of the structure of DNA in the 1950s and the invention of DNA sequencing in the 1970s, a huge number of scientific advances driven by breakthroughs made using sequencing technologies have been made. More recently, the advent and advances in second and third generation sequencing technologies have enabled new insights into genomic ...
openaire   +2 more sources