Results 231 to 240 of about 300,344 (255)

DNA Sequencing and the Third-Generation Sequencing Revolution

Since the discovery of the structure of DNA in the 1950s and the invention of DNA sequencing in the 1970s, a huge number of scientific advances driven by breakthroughs made using sequencing technologies have been made. More recently, the advent and advances in second and third generation sequencing technologies have enabled new insights into genomic ...
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Next-Generation and Third-Generation Sequencing of Lung Cancer Biomarkers

2017
In lung cancer, biomarker-guided therapy selection has greatly improved patient outcome. The recent introduction of next-generation sequencing (NGS) technology has rapidly expanded our understanding of disease-driving gene mutations and resulted in identification of key lung cancer biomarkers.
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The impact of third generation sequencing on haplotype assembly

The genome encompasses an organism’s full DNA, organized into chromosomes within the cell nucleus. Humans have 46 paired chromosomes, and within these pairs, genetic information is grouped as haplotypes—genetic packages passed from one generation to the next, ensuring genetic diversity. While DNA sequencing produces short fragments or reads, assembling
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Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection

Annual Review of Pathology: Mechanisms of Disease, 2019
Wei Gu, Steve Miller, Charles Y. Chiu
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Going Viral: Next-Generation Sequencing Applied to Phage Populations in the Human Gut

Nature Reviews Microbiology, 2012
Nicholas P Semenkovich, Jeffrey I. Gordon, Katrine Whiteson   +2 more
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Next-Generation Sequencing: Does the Next Generation Still Have a Right to an Open Future?

Nature Reviews Genetics, 2013
Martine de Vries, Johannes van Delden, Annelien Bredenoord   +2 more
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Advances in Understanding Cancer Genomes Through Second-Generation Sequencing

Nature Reviews Genetics, 2010
Gad Getz, Matthew Meyerson, Stacey Gabriel   +2 more
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The Role of Replicates for Error Mitigation in Next-Generation Sequencing

Nature Reviews Genetics, 2014
George Church, Nathan E. Lewis, Kimberly Robasky   +2 more
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Coming of Age: Ten Years of Next-Generation Sequencing Technologies

Nature Reviews Genetics, 2016
John McPherson, Sara Goodwin, William Richard McCombie   +2 more
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Genome-Wide Genetic Marker Discovery and Genotyping Using Next-Generation Sequencing

Nature Reviews Genetics, 2011
John W Davey, Julian Catchen, Paul A. Hohenlohe   +2 more
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