Zoonotic Infection with Oz Virus, a Novel Thogotovirus [PDF]
Oz virus is a novel thogotovirus isolated from ticks that causes lethal infection in mice. We conducted serosurveillance of Oz virus infection among humans and wild mammals in Japan using virus-neutralization tests and ELISAs.
Ngo T.B. Tran +14 more
doaj +5 more sources
Eight Years of Research Advances in Bourbon Virus, a Tick-borne Thogotovirus of the Orthomyxovirus Family [PDF]
Bourbon virus (BRBV) was first isolated from a blood sample collected from a male patient living in Bourbon County, Kansas, during the spring of 2014. The patient later died because of complications associated with multiorgan failure.
Siyuan Hao +5 more
doaj +3 more sources
Comprehensive Review of Emergence and Virology of Tickborne Bourbon Virus in the United States [PDF]
The emergence of SARS-CoV-2 and the worldwide COVID-19 pandemic triggered considerable attention to the emergence and evolution of novel human pathogens. Bourbon virus (BRBV) was first discovered in 2014 in Bourbon County, Kansas, USA. Since its initial
Molly K. Roe +6 more
doaj +2 more sources
Experimental and evolutionary evidence for horizontal transfer of an envelope fusion protein gene between thogotoviruses and baculoviruses [PDF]
Baculoviruses are insect-specific viruses with large, double-stranded DNA genomes classified into four genera. Alphabaculoviruses, which infect lepidoptera, are further divided into group I (G1-α) and group II (G2-α). The GP64 protein, essential for cell
Bruno Milhomem Pilati Rodrigues +5 more
doaj +2 more sources
Characterization of Viral Communities of Biting Midges and Identification of Novel Thogotovirus Species and Rhabdovirus Genus [PDF]
More than two thirds of emerging viruses are of zoonotic origin, and among them RNA viruses represent the majority. Ceratopogonidae (genus Culicoides) are well-known vectors of several viruses responsible for epizooties (bluetongue, epizootic ...
Sarah Temmam +9 more
doaj +5 more sources
Involvement of a tick-borne orthomyxovirus matrix protein in vRNP nuclear export [PDF]
Thogotoviruses are arthropod-borne viruses belonging to the genus Thogotovirus within the family Orthomyxoviridae. Like other orthomyxoviruses, such as the influenza A viruses (IAV), thogotoviruses replicate in the nucleus.
Vaille A. Swenson +6 more
doaj +2 more sources
Infections with emerging and re-emerging arboviruses are of increasing concern for global health. Tick-transmitted RNA viruses of the genus Thogotovirus in the Orthomyxoviridae family have considerable zoonotic potential, as indicated by the recent ...
Jonas Fuchs +3 more
doaj +5 more sources
ANP32 proteins from ticks and vertebrates are key host factors for replication of Bourbon virus across species [PDF]
Bourbon virus (BRBV) is a tick-borne virus in the genus Thogotovirus in the Orthomyxoviridae family. BRBV was initially identified as the presumptive causative agent of a fatal human infection in 2014 and has since been identified in ticks in the Midwest,
Zhenyu Zhang +4 more
doaj +2 more sources
Novel Thogotovirus Associated with Febrile Illness and Death, United States, 2014
A previously healthy man from eastern Kansas, USA, sought medical care in late spring because of a history of tick bite, fever, and fatigue. The patient had thrombocytopenia and leukopenia and was given doxycycline for a presumed tickborne illness.
Olga I. Kosoy +6 more
doaj +3 more sources
Comparative Study of Ten Thogotovirus Isolates and Their Distinct In Vivo Characteristics. [PDF]
Since their discovery over 60 years ago, 15 genetically distinct members of the thogotovirus genus have been isolated. These arboviruses belong to the Orthomyxovirus family and share many features with influenza viruses.
Fuchs J +5 more
europepmc +4 more sources

