Results 41 to 50 of about 18,631,052 (336)

The nonlinear bending-torsion theory for curved rods as Gamma-limit of three-dimensional elasticity [PDF]

, 2006
The problem of the rigorous derivation of one-dimensional models for nonlinearly elastic curved beams is studied in a variational setting. Considering different scalings of the three-dimensional energy and passing to the limit as the diameter of the beam
Scardia, L.
core   +6 more sources

Recent Advances in Three-Dimensional Stem Cell Culture Systems and Applications

Stem Cells International, 2021
Cell culture is one of the most core and fundamental techniques employed in the fields of biology and medicine. At present, although the two-dimensional cell culture method is commonly used in vitro, it is quite different from the cell growth ...
Xiaowen Wu, Junxiang Su, Jizhen Wei, Nan Jiang, Xuejun Ge   +4 more
doaj   +1 more source

Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network

Nature Communications, 2017
In native tissues, cellular and acellular components are anisotropically organized and often aligned in specific directions, providing structural and mechanical properties for actuating biological functions.
So Hyun Kim, Sun-Kyoung Im, S. Oh, Sohyeon Jeong, E. Yoon, C. J. Lee, Nakwon Choi, Eun-Mi Hur   +7 more
semanticscholar   +1 more source

Initiation, Expansion, and Cryopreservation of Human Primary Tissue‐Derived Normal and Diseased Organoids in Embedded Three‐Dimensional Culture

Current Protocols in Cell Biology, 2018
Organoids are primary patient‐derived micro tissues grown within a three‐dimensional extracellular matrix that better represents in vivo physiology and genetic diversity than existing two‐dimensional cell lines.
James M. Clinton, P. McWilliams-Koeppen
semanticscholar   +1 more source

Recent Advances in Three-Dimensional Multicellular Spheroid Culture and Future Development

Micromachines, 2021
Three-dimensional multicellular spheroids (MCSs) have received extensive attention in the field of biomedicine due to their ability to simulate the structure and function of tissues in vivo more accurately than traditional in vitro two-dimensional models
Honglin Shen, Shuxiang Cai, Chuanxiang Wu, Wenguang Yang, Haibo Yu, Lianqing Liu   +5 more
doaj   +1 more source

Three-Dimensional Human Neural Cell Culture Using Tailored Porous Polymer Scaffolds

, 2019
The culture of cells in flat, stiff, two-dimensional environments often results in cells dissimilar to those found in the human body. This can be detrimental in the translation of research outcomes from dish to human, and is particularly evident in the ...
ASHLEY RYAN MURPHY (6373568)
core   +1 more source

The Hollow Porous Sphere Cell Carrier for the Dynamic Three-Dimensional Cell Culture [PDF]

, 2022
Large-scale mammalian cell culture is essential in cell therapy, vaccine production, and the manufacturing of therapeutic protein drugs. Due to the adherent growth characteristic of most mammalian cell types, the combination of cell carrier and ...
Yarlagadda, Prasad, Xiao, L, Xiao, Lan, Wang, Jiaqiu, Wu, Chengtie, Xiao, Yin, Mendhi, Jayanti, Gao, Weidong, Wu, C, Mu, Y, Mendhi, J, Li, Zhiyong, Wang, J, Yarlagadda, P, Mu, Yuqing, Li, Z, Gao, Wendong, Gao, W, Xiao, Y   +18 more
core   +1 more source

Engineering extracellular vesicles by three‐dimensional dynamic culture of human mesenchymal stem cells

Journal of Extracellular Vesicles, 2022
Human mesenchymal stem cell (hMSC) derived extracellular vesicles (EVs) have shown therapeutic potential in recent studies. However, the corresponding therapeutic components are largely unknown, and scale‐up production of hMSC EVs is a major challenge ...
Xuegang Yuan, Li Sun, Richard Jeske, Dingani Nkosi, Sara B. York, Yuan Liu, Samuel C. Grant, David G. Meckes Jr, Yan Li   +8 more
doaj   +1 more source

Evaluation of bovine uterine gland functions in 2D and 3D culture system

The Journal of Reproduction and Development, 2022
In ruminants, uterine glands play key roles in the establishment of pregnancy by secreting various factors into the uterine lumen. Although a three-dimensional (3D) culture system has been used for investigating cellular functions in vitro, the detailed ...
Yosuke SUGINO, Taiki SATO, Yuki YAMAMOTO, Koji KIMURA   +3 more
doaj   +1 more source

A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance

Science Advances, 2016
A three-dimensional cell culture model of syncytiotrophoblasts recapitulates their secretory, morphological, and microbial resistance phenotypes.
Cameron A. McConkey, Elizabeth Delorme-Axford, C. Nickerson, K. Kim, Y. Sadovsky, J. Boyle, Carolyn B. Coyne   +6 more
semanticscholar   +1 more source