Results 71 to 80 of about 18,631,052 (336)
Mimicking Epithelial Tissues in Three-Dimensional Cell Culture Models
Epithelial tissues are composed of layers of tightly connected cells shaped into complex three-dimensional (3D) structures such as cysts, tubules, or invaginations.
Núria Torras +5 more
doaj +1 more source
Microfluidic Invasion Chemotaxis Platform for 3D Neurovascular Co-Culture
Advances in microfabrication and biomaterials have enabled the development of microfluidic chips for studying tissue and organ models. While these platforms have been developed primarily for modeling human diseases, they are also used to uncover cellular
Emel Sokullu +5 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Whole organ culture of the spiral ganglion region is a resourceful model system facilitating manipulation and analysis of live sprial ganglion neurons (SGNs).
Gaoying Sun +12 more
semanticscholar +1 more source
In Vitro Three-dimensional (3D) Cell Culture Tools for Spheroid and Organoid Models.
Three-dimensional (3D) cell culture technology has been steadily studied since the 1990's due to its superior biocompatibility compared to the conventional two-dimensional (2D) cell culture technology, and has recently developed into an organoid culture ...
Sang‐Yun Lee +3 more
semanticscholar +1 more source
Three-dimensional instability in flow over a backward-facing step [PDF]
Results are reported from a three-dimensional computational stability analysis of flow over a backward-facing step with an expansion ratio (outlet to inlet height) of 2 at Reynolds numbers between 450 and 1050.
Gomes, M. Gabriela M. +2 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Three-dimensional culture models of mammary gland [PDF]
The mammary gland is a complex tissue comprised of a branching network of ducts embedded within an adipocyte-rich stroma. The ductal epithelium is a bi-layer of luminal and myoepithelial cells, the latter being in contact with a basement membrane. During pregnancy, tertiary branching occurs and lobuloalveolar structures, which produce milk during ...
Jonathan J, Campbell +1 more
openaire +2 more sources
The use of three-dimensional cell culture to study apicobasal polarization and lumen formation
The three-dimensional culture of epithelial cells allows the characterization of processes required for collective epithelial polarization, such as formation of an epithelial lumen.
Bryant, David M. +2 more
core +1 more source

