Decreased Thrombin Generation is Associated with Increased Thrombin Generation Biomarkers and Blood Cellular Indices in Pulmonary Embolism. [PDF]
Siddiqui F +8 more
europepmc +1 more source
Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma
Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan +4 more
wiley +1 more source
Thrombin Generation Is Associated With Extracellular Vesicle and Leukocyte Lipid Membranes in Atherosclerotic Cardiovascular Disease. [PDF]
Protty MB +13 more
europepmc +1 more source
Abstract Introduction Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green‐colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.
Samantha C. Redden +6 more
wiley +1 more source
The impact of rapid infusers on the hemostatic potential of cryoprecipitate products
Abstract Background In cases of massive transfusion, intravenous access can be limited. Additionally, delivering different products through separate lines and infusion methods adds unnecessary steps. RBC, plasma, and whole blood (WB) are delivered via rapid infusers; cryoprecipitate (CRYO) is infused through separate access and is not approved with ...
Connor D. Purvis +7 more
wiley +1 more source
Comparison of the Calibrated Automated Thrombogram Using Standard and Low Plasma Volumes in Dogs
ABSTRACT Background Thrombin generation assessment using calibrated automated thrombography (CAT) requires a standard volume of plasma (80 μL) and reagent (20 μL) run in triplicate. A CAT method using lower plasma and reagent volumes could benefit veterinary patients as it lowers the sampling burden in patients.
Erin M. Phillips +5 more
wiley +1 more source
A cell-based model to study mechanisms of endothelial-dependent thrombin generation in response to inflammation and its modulation by hydroxychloroquine. [PDF]
Arachchillage DJ +5 more
europepmc +1 more source
Abstract Objective To determine and compare the fixation strength of conjunctival pedicle flaps to cornea achieved via conventional ophthalmic suture and three different adhesive compounds. Animals Studied Ex vivo porcine globes. Procedures Following a 6 mm wide 500‐micron‐restricted depth lamellar keratectomy, conjunctival pedicle flaps were secured ...
Elodie M. VerHulst +4 more
wiley +1 more source
Clot lysis time and thrombin generation in patients undergoing transcatheter aortic valve implantation. [PDF]
Siniarski A +5 more
europepmc +1 more source

