Results 181 to 190 of about 100,897 (348)

The Phosphatase Inhibitor Calyculin-A Impairs Clot Retraction, Platelet Activation, and Thrombin Generation [PDF]

, 2017
Renáta Hudák, János Vincze, László Csernoch, Ildikó Beke Debreceni, Tamás Oláh, Ferenc Erdődi, Kenneth J. Clemetson, János Kappelmayer   +7 more
openalex   +1 more source

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

Equine Veterinary Journal, EarlyView.
Abstract Background African horse sickness (AHS), caused by the vector‐borne African horse sickness virus (AHSV), is endemic to sub‐Saharan Africa and infection results in high mortality in naïve equine populations. Clinical signs include submucosal petechiae and prolonged bleeding post venepuncture indicative of hypocoagulation.
Eva Christina Schliewert, Emma H. Hooijberg, Amelia Goddard   +2 more
wiley   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Emicizumab, the factor VIII mimetic bispecific monoclonal antibody: effects on thrombin generation and thromboelastometry. [PDF]

Res Pract Thromb Haemost
Tripodi A, Clerici M, Scalambrino E, Arcudi S, Gualtierotti R, Novembrino C, Peyvandi F.   +6 more
europepmc   +1 more source

Comparison of thrombin generation for paired‐platelet‐rich plasma collected with and without corn trypsin inhibitor from hemophiliacs treated with factor‐VIII inhibitor bypassing agents [PDF]

, 2012
Armando Tripodi, Veena Chantarangkul, Maria Elisa Mancuso, Laura Lemma, Marigrazia Clerici, Elena Santagostino   +5 more
openalex   +1 more source

Treatment of large chondral lesions with an autologous minced cartilage technique and synovial flap leads to superior results compared to matrix associated autologous chondrocyte transplantation technique after 24 months: A controlled clinical trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Treating large cartilage lesions in the knee remains a challenge. While matrix‐associated autologous chondrocyte implantation (MACI) is the gold standard for medium to large lesions, the minced cartilage technique has shown promise in smaller defects. Enhancing this technique with biomaterials has been suggested for larger lesions, but
Johanna Mayr, Franziska Warth, Nicola Oehler, Martin Majewski, Christoph Lutter, Fabian Blanke   +5 more
wiley   +1 more source

Thrombin generation in HeartMate 3 patients on apixaban and vitamin K antagonists: Variability limits clinical applicability. [PDF]

JHLT Open
Van Edom CJ, Droogné W, Jacobs S, Jacquemin M, Van Laer C, Van Puyvelde J, Vlasselaers D, Vandersmissen K, Vanassche T, Meyns B.   +9 more
europepmc   +1 more source

Whole blood thrombin generation profiles of patients with cirrhosis explored with a near patient assay [PDF]

, 2020
Jun Wan, Lara N. Roberts, Wasiliki Hendrix, Joke Konings, Tsai‐Wing Ow, Liane Rabinowich, Omar Barbouti, Bas de Laat, Roopen Arya, Vishal Patel, Mark Roest, Ton Lisman, William Bernal   +12 more
openalex   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

High incidence of thrombin generation resistance to thrombomodulin in patients with unprovoked venous thromboembolism. [PDF]

Blood Vessel Thromb Hemost
Gris JC, Chea M, Nouvellon E, De Jouvancourt R, Fortier M, Bourguignon C, Laurent J, Bouvier S, Perez-Martin A.   +8 more
europepmc   +1 more source