Results 101 to 110 of about 4,457,527 (301)

Health and economic benefits of improving pre‐hospital identification of stroke in Australian women: a modelling study

Medical Journal of Australia, EarlyView.
Abstract Objective To estimate the long term gains in life years and quality‐adjusted life years (QALYs) and the cost savings that could be achieved if ischaemic stroke was identified in women with the same level of accuracy received by men, versus the status quo. Design Decision tree and Markov model decision analysis.
Thomas Gadsden, Lei Si, Emily R Atkins, Cheryl Carcel, Xia Wang, Stephen Jan, Mark Woodward, Laura E Downey   +7 more
wiley   +1 more source

Thrombolytic therapy in review

The Journal of Emergency Medicine, 1993
The use of thrombolytic agents for both coronary and noncoronary indications is a rapidly progressing field. There has been substantial debate over which disease processes ultimately benefit from the use of thrombolytic agents. In addition, many recent studies have focused on comparing different thrombolytic agents and dosing regimens in an attempt to ...
Department of Emergency Medicine, East Carolina University School of Medicine/ University Medical Center of Eastern Carolina, Greenville, North Carolina, USA ( host institution ), Thomas, Stephen H. ( author ), Shepherd, Suzanne M. ( author ), Allison, E.Jackson ( author )   +3 more
openaire   +4 more sources

Is primary angioplasty cost effective in the UK? Results of a comprehensive decision analysis [PDF]

, 2007
Objective: To assess the cost effectiveness of primary angioplasty, compared with medical management with thrombolytic drugs, to achieve reperfusion after acute myocardial infarction ( AMI) from the perspective of the UK NHS.
Abrams, Keith, Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +2 more sources

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, Volume 12, Issue 25, July 3, 2025.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]

, 2014
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy, Eastwood, Jo-Ann, Gylys, Karen, Meyer, Dawn M, Zivin, Justin A   +4 more
core   +3 more sources

Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Chest, 2012
BACKGROUND This article addresses the treatment of VTE disease. METHODS We generated strong (Grade 1) and weak (Grade 2) recommendations based on high-quality (Grade A), moderate-quality (Grade B), and low-quality (Grade C) evidence.
C. Kearon, E. Akl, A. Comerota, P. Prandoni, H. Bounameaux, S. Goldhaber, M. E. Nelson, P. Wells, M. Gould, F. Dentali, M. Crowther, S. Kahn   +11 more
semanticscholar   +1 more source

Debate: Should the elderly receive thrombolytic therapy or primary angioplasty?

Current Controlled Trials in Cardiovascular Medicine, 2000
Thrombolysis and primary angioplasty are both recommended reperfusion strategies for elderly patients presenting with myocardial infarction (MI). Primary angioplasty is most beneficial in high-risk patients. While the elderly have a high absolute risk of
White Harvey D
doaj   +1 more source

Deadline Effect in Stroke Patient Care: A Temporal Motivation Theory Perspective of Process Management

Journal of Operations Management, Volume 71, Issue 5, Page 670-699, July 2025.
ABSTRACT Stroke is a highly time‐sensitive medical emergency, and earlier treatment is crucial. Drawing on Temporal Motivation Theory, we investigate a “deadline effect” in stroke care and analyze how two deadlines, that is, a medically oriented one (administering Tissue Plasminogen Activator, TPA, within 4.5 h of symptom onset) and a goal‐oriented one
Brandon Lee, Seokjun Youn, Lawrence Fredendall   +2 more
wiley   +1 more source

Comparison of predictive scores of symptomatic intracerebral haemorrhage after stroke thrombolysis in a single centre [PDF]

, 2015
Peer reviewedPublisher ...
Dai, D., MacLeod, MJ, Reid, J. M., Watson-Fargie, T.   +3 more
core   +1 more source

Modern methods for the estimation of thrombolysis efficiency in patients with myocardial infraredness with the rise of ST

Лечащий Врач, 2021
This article presents a literature review dedicated to modern methods of noninvasive evaluation of efficacy of thrombolytic therapy in patients with ST-segment elevation in myocardial infarction. D-dimer as a probable marker of myocardial reperfusion and
E. M. Podgornaya, L. I. Markova, O. L. Belaya, K. I. Tebloev   +3 more
doaj