Results 81 to 90 of about 67,161 (291)

Carotid Endarterectomy in the Acute Period of Ischemic Stroke After Thrombolytic Therapy

Неотложная медицинская помощь
AIM OF STUDY. To study the outcomes, complications and risk factors of CEA surgery in patients after thrombolytic therapy.MATERIAL AND METHODS. The results of treatment of patients after carotid endarterectomy in the acute period of ischemic acute ...
D. А. Nekrasov, D. Ya. Ziyarova, A. V. Gavrilenko   +2 more
doaj   +1 more source

Orbital and intracranial hemorrhage following thrombolysis: A case report

Journal of Clinical Ophthalmology and Research, 2015
Thrombolytic therapy has been a major advance in the treatment of acute myocardial infarction to achieve coronary reperfusion and improve survival. Bleeding is the most common complication following thrombolytic therapy which can occur spontaneously and ...
Karuppannasamy Divya, Kanagaraju Vikrant, Andavar Raghuram, Tamilmani Yazhini   +3 more
doaj   +1 more source

Systemic thrombolytic therapy for acute pulmonary embolism: a systematic review and meta-analysis [PDF]

, 2017
Aim Thrombolytic therapy induces faster clot dissolution than anticoagulation in patients with acute pulmonary embolism (PE) but is associated with an increased risk of haemorrhage.
Combescure, Christophe, John, Gregor, Konstantinides, Stavros, Lankeit, Mareike, Marti, Christophe, Meyer, Guy, Perrier, Arnaud, Sanchez, Olivier   +7 more
core  

Professional guideline versus product label selection for treatment with IV thrombolysis: an analysis from SITS registry [PDF]

, 2017
Introduction: Thrombolysis usage in ischaemic stroke varies across sites. Divergent advice from professional guidelines and product labels may contribute. Patients and methods: We analysed SITS-International registry patients enrolled January 2010
Alan C Cameron, Azmil H Abdul-Rahim, James Bogie, Kennedy R Lees, Michael Mazya, Niaz Ahmed, null null, Robert Mikulik, Werner Hacke   +8 more
core   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]

, 2011
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Barrie Condon, Celestine Santosh, Christopher McCabe, Craig A Robertson, I Mhairi Macrae, Keith W Muir, Kucinski T, Lindsay Gallagher, Maria del Rosario Lopez-Gonzalez, William M Holmes   +9 more
core   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

Lipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao, Nuan Wang, Di Shi, Hao Zhou, Dan Chen, Guofang Chen   +5 more
wiley   +1 more source

A performance evaluation of commercial fibrinogen reference preparations and assays for Clauss and PT-derived fibrinogen [PDF]

, 2002
The wide availability of fibrinogen estimations based on the prothrombin time (PT-Fg) has caused concern about the variability and clinical utility of fibrinogen assays.
Gaffney, P.J., Howarth, D., Kitchen, S., Lawrie, A.S., Lowe, G.D.O., Mackie, I.J., Martin, J., Purdy, G., Rigsby, P., Rumley, A.   +9 more
core   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study [PDF]

, 2007
<p><b>Background and Purpose:</b> Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke.</p> <p><b>Methods:</b> We retrospectively analyzed ...
McCormick, M., Moreton, F.C., Muir, K.W.
core   +1 more source